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F4F3N9 (F4F3N9_VERMA) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phenylalanine--tRNA ligase alpha subunit HAMAP-Rule MF_00281
EC=6.1.1.20 HAMAP-Rule MF_00281
Alternative name(s):
Phenylalanyl-tRNA synthetase alpha subunit HAMAP-Rule MF_00281
Gene names
Name:pheS HAMAP-Rule MF_00281 EMBL AEB44147.1
Ordered Locus Names:VAB18032_15175 EMBL AEB44147.1
OrganismVerrucosispora maris (strain AB-18-032) [Complete proteome] [HAMAP]
Taxonomic identifier263358 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Verrucosispora ›

Protein attributes

Sequence length355 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). HAMAP-Rule MF_00281 SAAS SAAS004529

Cofactor

Binds 2 magnesium ions per tetramer By similarity. HAMAP-Rule MF_00281 SAAS SAAS004529

Subunit structure

Tetramer of two alpha and two beta subunits By similarity. HAMAP-Rule MF_00281 SAAS SAAS004529

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00281 SAAS SAAS004529.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. HAMAP-Rule MF_00281

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2731Magnesium By similarity HAMAP-Rule MF_00281

Sequences

Sequence LengthMass (Da)Tools
F4F3N9 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: 956AAFCF06FA3B9F

FASTA35539,390
        10         20         30         40         50         60 
MTYRNDPYDP KQVALLDPAA LAEAVTEAEK AFAAAGDPDA LAAVRPAHLG DRAPVSLARR 

        70         80         90        100        110        120 
EIGALPPAAK ADAGKRVNEA RRSIEQAYAA RSEVLDREQA QRVLVAERVD VTLPYDRRPR 

       130        140        150        160        170        180 
GSRHPVSVLM EQISDLFIGM GYEVAEGPEV ELEWTNFDAL NIPVDHPARG LMDTFHIAPE 

       190        200        210        220        230        240 
QSGLVLRTHT SPVQARTMLT RQPPIYVVVP GRVYRTDELD ATHSPVFHQV EGLVVDKGIT 

       250        260        270        280        290        300 
MAHLRGTLDH FARAMFGEGA KTRFRPHYFP FTEPSAEFDV WFPEHRKGPQ WVEWGGCGMV 

       310        320        330        340        350 
NPRVLRACGI DPEVYSGFAF GMGIDRTVMF RHGVGDMRDM VEGDVRFTRA FGHGA

« Hide

References

[1]"Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032."
Roh H., Uguru G.C., Ko H.J., Kim S., Kim B.Y., Goodfellow M., Bull A.T., Kim K.H., Bibb M.J., Choi I.G., Stach J.E.
J. Bacteriol. 193:3391-3392(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AB-18-032 EMBL AEB44147.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002638 Genomic DNA. Translation: AEB44147.1.
RefSeqYP_004404747.1. NC_015434.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEB44147; AEB44147; VAB18032_15175.
GeneID10450913.
KEGGvma:VAB18032_15175.
PATRIC54472618. VBIVerMar92278_2191.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01889.

Family and domain databases

HAMAPMF_00281. Phe_tRNA_synth_alpha1.
InterProIPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_ligase_II_N.
IPR022911. Phe_tRNA_ligase_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view]
PfamPF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SUPFAMSSF46589. tRNA_binding_arm. 1 hit.
TIGRFAMsTIGR00468. pheS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF4F3N9_VERMA
AccessionPrimary (citable) accession number: F4F3N9
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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