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F4ERQ1

- F4ERQ1_BACAM

UniProt

F4ERQ1 - F4ERQ1_BACAM

Protein

Thymidine kinase

Gene

tdk

Organism
Bacillus amyloliquefaciens LL3
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (28 Jun 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei89 – 891Proton acceptorUniRule annotation
    Metal bindingi145 – 1451ZincUniRule annotation
    Metal bindingi148 – 1481ZincUniRule annotation
    Metal bindingi183 – 1831ZincUniRule annotation
    Metal bindingi186 – 1861ZincUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi15 – 228ATPUniRule annotation
    Nucleotide bindingi88 – 914ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. thymidine kinase activity Source: UniProtKB-HAMAP
    3. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding, ZincUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciBAMY1001582:GL8C-3944-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:tdkUniRule annotationImported
    ORF Names:LL3_03854Imported
    OrganismiBacillus amyloliquefaciens LL3Imported
    Taxonomic identifieri1001582 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000000308: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    KOiK00857.

    Family and domain databases

    HAMAPiMF_00124. Thymidine_kinase.
    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F4ERQ1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYIMKQSGWL ELICGSMFSG KSEELIRRVK RATYAKQEVK VFKPAIDNRY    50
    SEEAVVSHNG TSMTSHVISS SAEIWDHISE STDVIAVDEV QFFGESIIDD 100
    LSMLADKGYR VIAAGLDMDF RGEPFGVVPD LMAVAESVTK LQAVCSVCGS 150
    PASRTQRLID GKPASYDDPV ILVGASESYE ARCRHHHEVP KKQTDK 196
    Length:196
    Mass (Da):21,663
    Last modified:June 28, 2011 - v1
    Checksum:i0F571AE6C422FB2B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002634 Genomic DNA. Translation: AEB65380.1.
    RefSeqiWP_014471156.1. NC_017190.1.
    YP_005547608.1. NC_017190.1.

    Genome annotation databases

    EnsemblBacteriaiAEB65380; AEB65380; LL3_03854.
    GeneIDi12205297.
    KEGGibql:LL3_03854.
    PATRICi54319991. VBIBacAmy188832_3793.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002634 Genomic DNA. Translation: AEB65380.1 .
    RefSeqi WP_014471156.1. NC_017190.1.
    YP_005547608.1. NC_017190.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEB65380 ; AEB65380 ; LL3_03854 .
    GeneIDi 12205297.
    KEGGi bql:LL3_03854.
    PATRICi 54319991. VBIBacAmy188832_3793.

    Phylogenomic databases

    KOi K00857.

    Enzyme and pathway databases

    BioCyci BAMY1001582:GL8C-3944-MONOMER.

    Family and domain databases

    HAMAPi MF_00124. Thymidine_kinase.
    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of Bacillus amyloliquefaciens LL3, Which Exhibits Glutamic Acid-Independent Production of Poly-{gamma}-Glutamic Acid."
      Geng W., Cao M., Song C., Xie H., Liu L., Yang C., Feng J., Zhang W., Jin Y., Du Y., Wang S.
      J. Bacteriol. 193:3393-3394(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LL3Imported.

    Entry informationi

    Entry nameiF4ERQ1_BACAM
    AccessioniPrimary (citable) accession number: F4ERQ1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3