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F4DZ16 (F4DZ16_PSEMN) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length204 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair By similarity. HAMAP-Rule MF_00015 SAAS SAAS006197

Catalytic activity

Hydrolysis of Ala-|-Gly bond in repressor lexA. RuleBase RU003992 HAMAP-Rule MF_00015 SAAS SAAS019759

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00015 SAAS SAAS019759

Sequence similarities

Belongs to the peptidase S24 family. HAMAP-Rule MF_00015 RuleBase RU003991

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

DNA binding28 – 4821H-T-H motif By similarity HAMAP-Rule MF_00015

Sites

Active site1251For autocatalytic cleavage activity By similarity HAMAP-Rule MF_00015
Active site1621For autocatalytic cleavage activity By similarity HAMAP-Rule MF_00015
Site90 – 912Cleavage; by autolysis By similarity HAMAP-Rule MF_00015

Sequences

Sequence LengthMass (Da)Tools
F4DZ16 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: D6977D9CD3647012

FASTA20422,444
        10         20         30         40         50         60 
MLKLTPRQAE ILAFIKRCLE DNGYPPTRAE IAQELGFKSP NAAEEHLKAL ARKGAIEMTP 

        70         80         90        100        110        120 
GASRGIRIPG FEAGAANEDE GLPVIGRVAA GAPILAQQHV EESCQINPAF FQPKADYLLR 

       130        140        150        160        170        180 
VRGMSMKDIG IFDGDLLAVH TTREARNGQI VVARIDDEVT VKRFKREGNK VWLIAENPEF 

       190        200 
APIEVDLEHQ DLVIEGLSVG VIRR

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References

[1]"Complete genome of Pseudomonas mendocina NK-01, which synthesizes medium-chain-length polyhydroxyalkanoates and alginate oligosaccharides."
Guo W., Wang Y., Song C., Yang C., Li Q., Li B., Su W., Sun X., Song D., Yang X., Wang S.
J. Bacteriol. 193:3413-3414(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NK-01 EMBL AEB57671.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002620 Genomic DNA. Translation: AEB57671.1.
RefSeqYP_004379423.1. NC_015410.1.

3D structure databases

ModBaseSearch...

Protein family/group databases

MEROPSS24.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEB57671; AEB57671; MDS_1640.
GeneID10456422.
KEGGpmk:MDS_1640.
PATRIC54483878. VBIPseMen187712_1666.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01356.

Enzyme and pathway databases

BioCycPMEN1001585:GIWS-1653-MONOMER.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
2.10.109.10. 1 hit.
HAMAPMF_00015. LexA.
InterProIPR006199. LexA_DNA-bd_dom.
IPR006200. Pept_S24_LexA.
IPR006197. Peptidase_S24_LexA.
IPR019759. Peptidase_S24_S26.
IPR015927. Peptidase_S24_S26A/B/C.
IPR011056. Peptidase_S24_S26A/B/C_b-rbn.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF01726. LexA_DNA_bind. 1 hit.
PF00717. Peptidase_S24. 1 hit.
[Graphical view]
PRINTSPR00726. LEXASERPTASE.
SUPFAMSSF51306. Pept_S24_S26_C. 1 hit.
TIGRFAMsTIGR00498. lexA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF4DZ16_PSEMN
AccessionPrimary (citable) accession number: F4DZ16
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: May 1, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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