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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Aeromonas veronii (strain B565)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei543 – 5431UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciAVER998088:GHKF-410-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:B565_0391Imported
OrganismiAeromonas veronii (strain B565)Imported
Taxonomic identifieri998088 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
ProteomesiUP000000312: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiCGMGVIA.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F4D7G1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNEKYAALRA NVGMLGQLLG KSIKDHQGQA FLDKIETIRQ LAKSSRKGNE
60 70 80 90 100
SDRERLLDTL RTLSDDELLP VARAFSQFLN LANVAEQFHT ISRRCEEQVC
110 120 130 140 150
TPDPLEQMFD KLKASNLSQE AIIQAVRELD IDLVLTAHPT EVTRRTLIHK
160 170 180 190 200
HVQLNDCLEA LELSDLLPRE RDKILNRIEQ LINQAWHTNE IREQRPTPVD
210 220 230 240 250
EAKWGFAVVE NSLWPAIPEF MRNLDERLQH HLGVRLPLDA APVKFTSWMG
260 270 280 290 300
GDRDGNPFVT AKVTAEVLEL GRWMAVSLFY KDIKELTSEL SMSDCTDAVR
310 320 330 340 350
ARVGDHPEPY RALVRELREA LRETKEHLTA KVQGQASESQ DLVKTTAQLR
360 370 380 390 400
EPLELCYHSL HACGMGNIAD GMLLDVLRKV ACFGIHLVKL DIRQDGERHG
410 420 430 440 450
LVFSELTRYL GLGDYAEWSE DDKQAFLLNE LNSRRPLIPH DWEPSAEVRE
460 470 480 490 500
TLDTCQVIAE HDPDAFGIYI ISMAGAPSDV LSVQLLLKEA GCKFRMPVAP
510 520 530 540 550
LFETQDDLMA GTAVMERLLS VDWYRGYIQG RQYVMIGYSD SAKDAGMMAA
560 570 580 590 600
GWAQYAAMES LVGLAEANNI RLTLFHGRGG TVGRGGAPAH QAILSQPPGS
610 620 630 640 650
LRGGLRTTEQ GEMIRFKFGL PKVAIKSLEL YTSAVLEGNL LPPPKPKECW
660 670 680 690 700
REVMEQLAAD SCDHYRSIVR GHPDFVPYFR AATPEMELGK LPLGSRPSKR
710 720 730 740 750
KPNGGVESLR AIPWIFAWTQ NRLMLPAWLG AHKALQQAID GGKLAVLEEM
760 770 780 790 800
SAQWPFFRTR LEMLEMVFLK ADVWLAEYYD TRLVPQELWG LGKQLRQELA
810 820 830 840 850
ESIEVVLKLS TRGDLLEDQP WIKESIKLRN PYTDPLNVLQ AELLNRSRNH
860 870
PETLHPELDK ALMVTIAGIA AGMRNTG
Length:877
Mass (Da):98,820
Last modified:June 28, 2011 - v1
Checksum:i8A706112A8FED517
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002607 Genomic DNA. Translation: AEB48426.1.
RefSeqiYP_004391043.1. NC_015424.1.

Genome annotation databases

EnsemblBacteriaiAEB48426; AEB48426; B565_0391.
GeneIDi10486308.
KEGGiavr:B565_0391.
PATRICi54533330. VBIAerVer186715_0395.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002607 Genomic DNA. Translation: AEB48426.1.
RefSeqiYP_004391043.1. NC_015424.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEB48426; AEB48426; B565_0391.
GeneIDi10486308.
KEGGiavr:B565_0391.
PATRICi54533330. VBIAerVer186715_0395.

Phylogenomic databases

KOiK01595.
OMAiCGMGVIA.

Enzyme and pathway databases

BioCyciAVER998088:GHKF-410-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Aeromonas veronii strain B565."
    Li Y., Liu Y., Zhou Z., Huang H., Ren Y., Zhang Y., Li G., Zhou Z., Wang L.
    J. Bacteriol. 193:3389-3390(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: B565Imported.

Entry informationi

Entry nameiF4D7G1_AERVB
AccessioniPrimary (citable) accession number: F4D7G1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: February 4, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.