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F4CW85

- F4CW85_PSEUX

UniProt

F4CW85 - F4CW85_PSEUX

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Protein
Alanine racemase
Gene
Psed_5369
Organism
Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei63 – 631Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei161 – 1611Substrate By similarityUniRule annotation
Active sitei292 – 2921Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei342 – 3421Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciPDIO675635:GHMF-5419-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Psed_5369Imported
OrganismiPseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190)Imported
Taxonomic identifieri675635 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaePseudonocardia
ProteomesiUP000007809: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei63 – 631N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF4CW85.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01775.
OMAiIYSHLAL.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F4CW85-1 [UniParc]FASTAAdd to Basket

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MGGGARPDGV VGGCDDAGVA QPSMSDRGPR AELVVDLAAV RHNVGLLSRG    50
AAASGAATMA VVKSDGYGHG AADVARAALQ AGASWLGVCT LDEALALRAD 100
GIEAPVLSWL HLPHEDFAPA VAAGVDLSVS SHGHLDAVLA GARAVDRPAR 150
LHLKIDTGLS RNGCPEDDWP DLVDAAAKAA AAGRCEVVAV WSHLAVADVA 200
RHPVTEAQAA RFDAAWRVAR DRGLTPIRHL ANSAATMTRP DLHYDLVRPG 250
IAVYGLDPLG RPVAESPLRP AMTVRGRVVL VKQVRAGEGV SYGHEFTTPR 300
DTVLALVPIG YGDGVPRRMN FGGRMRVWLA GRSRPVVGRV CMDQVVVDCG 350
PDGGAEVREG DVAVLFGPGD DGAPTAQEWA DELGTIHYEV VTGVQGRRMT 400
RTVVGREAGP GTEQEGAAW 419
Length:419
Mass (Da):43,622
Last modified:June 28, 2011 - v1
Checksum:iED01A9FFF64D6AE4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002593 Genomic DNA. Translation: AEA27503.1.
RefSeqiWP_013677408.1. NC_015312.1.
YP_004335356.1. NC_015312.1.

Genome annotation databases

EnsemblBacteriaiAEA27503; AEA27503; Psed_5369.
GeneIDi10367220.
KEGGipdx:Psed_5369.
PATRICi54402366. VBIPseDio141225_5443.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002593 Genomic DNA. Translation: AEA27503.1 .
RefSeqi WP_013677408.1. NC_015312.1.
YP_004335356.1. NC_015312.1.

3D structure databases

ProteinModelPortali F4CW85.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEA27503 ; AEA27503 ; Psed_5369 .
GeneIDi 10367220.
KEGGi pdx:Psed_5369.
PATRICi 54402366. VBIPseDio141225_5443.

Phylogenomic databases

KOi K01775.
OMAi IYSHLAL.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci PDIO675635:GHMF-5419-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 55486 / DSM 44775 / JCM 13855 / CB1190.

Entry informationi

Entry nameiF4CW85_PSEUX
AccessioniPrimary (citable) accession number: F4CW85
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 3, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi