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F4CW85 (F4CW85_PSEUX) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site631Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2921Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1611Substrate By similarity HAMAP-Rule MF_01201
Binding site3421Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue631N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
F4CW85 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: ED01A9FFF64D6AE4

FASTA41943,622
        10         20         30         40         50         60 
MGGGARPDGV VGGCDDAGVA QPSMSDRGPR AELVVDLAAV RHNVGLLSRG AAASGAATMA 

        70         80         90        100        110        120 
VVKSDGYGHG AADVARAALQ AGASWLGVCT LDEALALRAD GIEAPVLSWL HLPHEDFAPA 

       130        140        150        160        170        180 
VAAGVDLSVS SHGHLDAVLA GARAVDRPAR LHLKIDTGLS RNGCPEDDWP DLVDAAAKAA 

       190        200        210        220        230        240 
AAGRCEVVAV WSHLAVADVA RHPVTEAQAA RFDAAWRVAR DRGLTPIRHL ANSAATMTRP 

       250        260        270        280        290        300 
DLHYDLVRPG IAVYGLDPLG RPVAESPLRP AMTVRGRVVL VKQVRAGEGV SYGHEFTTPR 

       310        320        330        340        350        360 
DTVLALVPIG YGDGVPRRMN FGGRMRVWLA GRSRPVVGRV CMDQVVVDCG PDGGAEVREG 

       370        380        390        400        410 
DVAVLFGPGD DGAPTAQEWA DELGTIHYEV VTGVQGRRMT RTVVGREAGP GTEQEGAAW 

« Hide

References

[1]"Genome sequence of the 1,4-dioxane-degrading Pseudonocardia dioxanivorans strain CB1190."
Sales C.M., Mahendra S., Grostern A., Parales R.E., Goodwin L.A., Woyke T., Nolan M., Lapidus A., Chertkov O., Ovchinnikova G., Sczyrba A., Alvarez-Cohen L.
J. Bacteriol. 193:4549-4550(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 55486 / DSM 44775 / JCM 13855 / CB1190.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002593 Genomic DNA. Translation: AEA27503.1.
RefSeqYP_004335356.1. NC_015312.1.

3D structure databases

ProteinModelPortalF4CW85.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEA27503; AEA27503; Psed_5369.
GeneID10367220.
KEGGpdx:Psed_5369.
PATRIC54402366. VBIPseDio141225_5443.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.
OMAIYSHLAL.

Enzyme and pathway databases

BioCycPDIO675635:GHMF-5419-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF4CW85_PSEUX
AccessionPrimary (citable) accession number: F4CW85
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: July 9, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)