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F4CW85

- F4CW85_PSEUX

UniProt

F4CW85 - F4CW85_PSEUX

Protein

Alanine racemase

Gene

Psed_5369

Organism
Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (28 Jun 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei63 – 631Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei161 – 1611SubstrateUniRule annotation
    Active sitei292 – 2921Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei342 – 3421Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciPDIO675635:GHMF-5419-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Psed_5369Imported
    OrganismiPseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190)Imported
    Taxonomic identifieri675635 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaePseudonocardia
    ProteomesiUP000007809: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei63 – 631N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliF4CW85.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.
    OMAiIYSHLAL.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F4CW85-1 [UniParc]FASTAAdd to Basket

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    MGGGARPDGV VGGCDDAGVA QPSMSDRGPR AELVVDLAAV RHNVGLLSRG    50
    AAASGAATMA VVKSDGYGHG AADVARAALQ AGASWLGVCT LDEALALRAD 100
    GIEAPVLSWL HLPHEDFAPA VAAGVDLSVS SHGHLDAVLA GARAVDRPAR 150
    LHLKIDTGLS RNGCPEDDWP DLVDAAAKAA AAGRCEVVAV WSHLAVADVA 200
    RHPVTEAQAA RFDAAWRVAR DRGLTPIRHL ANSAATMTRP DLHYDLVRPG 250
    IAVYGLDPLG RPVAESPLRP AMTVRGRVVL VKQVRAGEGV SYGHEFTTPR 300
    DTVLALVPIG YGDGVPRRMN FGGRMRVWLA GRSRPVVGRV CMDQVVVDCG 350
    PDGGAEVREG DVAVLFGPGD DGAPTAQEWA DELGTIHYEV VTGVQGRRMT 400
    RTVVGREAGP GTEQEGAAW 419
    Length:419
    Mass (Da):43,622
    Last modified:June 28, 2011 - v1
    Checksum:iED01A9FFF64D6AE4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002593 Genomic DNA. Translation: AEA27503.1.
    RefSeqiWP_013677408.1. NC_015312.1.
    YP_004335356.1. NC_015312.1.

    Genome annotation databases

    EnsemblBacteriaiAEA27503; AEA27503; Psed_5369.
    GeneIDi10367220.
    KEGGipdx:Psed_5369.
    PATRICi54402366. VBIPseDio141225_5443.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002593 Genomic DNA. Translation: AEA27503.1 .
    RefSeqi WP_013677408.1. NC_015312.1.
    YP_004335356.1. NC_015312.1.

    3D structure databases

    ProteinModelPortali F4CW85.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEA27503 ; AEA27503 ; Psed_5369 .
    GeneIDi 10367220.
    KEGGi pdx:Psed_5369.
    PATRICi 54402366. VBIPseDio141225_5443.

    Phylogenomic databases

    KOi K01775.
    OMAi IYSHLAL.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci PDIO675635:GHMF-5419-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 55486 / DSM 44775 / JCM 13855 / CB1190Imported.

    Entry informationi

    Entry nameiF4CW85_PSEUX
    AccessioniPrimary (citable) accession number: F4CW85
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3