ID   F4CVX7_PSEUX            Unreviewed;       661 AA.
AC   F4CVX7;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=DNA polymerase LigD, polymerase domain protein {ECO:0000313|EMBL:AEA25462.1};
GN   OrderedLocusNames=Psed_3272 {ECO:0000313|EMBL:AEA25462.1};
OS   Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 /
OS   CB1190).
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Pseudonocardia.
OX   NCBI_TaxID=675635 {ECO:0000313|EMBL:AEA25462.1, ECO:0000313|Proteomes:UP000007809};
RN   [1] {ECO:0000313|EMBL:AEA25462.1, ECO:0000313|Proteomes:UP000007809}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 55486 / DSM 44775 / JCM 13855 / CB1190
RC   {ECO:0000313|Proteomes:UP000007809};
RX   PubMed=21725009; DOI=10.1128/JB.00415-11;
RA   Sales C.M., Mahendra S., Grostern A., Parales R.E., Goodwin L.A., Woyke T.,
RA   Nolan M., Lapidus A., Chertkov O., Ovchinnikova G., Sczyrba A.,
RA   Alvarez-Cohen L.;
RT   "Genome sequence of the 1,4-dioxane-degrading Pseudonocardia dioxanivorans
RT   strain CB1190.";
RL   J. Bacteriol. 193:4549-4550(2011).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP002593; AEA25462.1; -; Genomic_DNA.
DR   AlphaFoldDB; F4CVX7; -.
DR   STRING; 675635.Psed_3272; -.
DR   KEGG; pdx:Psed_3272; -.
DR   eggNOG; COG1793; Bacteria.
DR   eggNOG; COG3285; Bacteria.
DR   HOGENOM; CLU_008325_0_2_11; -.
DR   Proteomes; UP000007809; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1490.70; -; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR   InterPro; IPR014144; LigD_PE_domain.
DR   InterPro; IPR014145; LigD_pol_dom.
DR   NCBIfam; TIGR02777; LigD_PE_dom; 1.
DR   NCBIfam; TIGR02778; ligD_pol; 1.
DR   PANTHER; PTHR42705; BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD; 1.
DR   PANTHER; PTHR42705:SF2; MULTIFUNCTIONAL NON-HOMOLOGOUS END JOINING DNA REPAIR PROTEIN LIGD; 1.
DR   Pfam; PF13298; LigD_N; 1.
DR   Pfam; PF21686; LigD_Prim-Pol; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007809}.
FT   DOMAIN          55..155
FT                   /note="DNA ligase D 3'-phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF13298"
FT   DOMAIN          387..645
FT                   /note="DNA ligase D polymerase"
FT                   /evidence="ECO:0000259|Pfam:PF21686"
FT   REGION          23..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          344..371
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        357..371
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   661 AA;  72328 MW;  BAB6CF917C62CF46 CRC64;
     MFAFGSPSHK ALSLTLVPLE EYRRKRDRSR TPEPVPDTDP AADGSDHDGG RFVVQEHHAS
     ALHWDVRLER DGVLVSWAVP KGLPVDTETV RLAVRTEDHP MEYLDFSGEI PAGEYGAGTM
     TIWDAGTYRT EKWSAREVAV VLQGQRARGR FVFVRSDRER RDGWILRRSD PGTARDPLPR
     DTLPMLATPG PLPLGDGWWL QVGFGGERVV VRVDGGRARF TDADGAELEV PALRAFGPTV
     GATPLLLDAE LVGNPRRDAV LWIGDLLHLD GRDTLDVPFA DRLALLEGLE LVGPAWRPAP
     AYRDAGQAVV DAAAEQGLPF VVAKRGDSPY RPGRRSDDWI EVATTAPAPA ARRDRPATAA
     RPGRRDGVGR ARLTNPDKVL YPLTGTTKAQ VLGHYLAVAE VMLPHLRDRP VTMVRWPDGV
     EKPSFFEKDV SRHAPGWIRT ARVGTPGGRS ESADFPLLDD AEGLAWAANL AALELHVPQW
     RVGPRGGRGL PDLVVFDLDP GEGANVVDCC RVAERIADLL AADGLSAHPR TSGSKGLQLY
     VPVTVSRAER TAEYARDIAA TVAGESPRTV TDVMAKARRR GKVFVDWSQN NPAKTTIASY
     SLRGRPRPTV ATPVTWDEVR ACRTVDDLVF TLDDLPGRIA EHGDLMAPLL FTERPRLPRR
     G
//