ID   F4C8R0_SPHS2            Unreviewed;       381 AA.
AC   F4C8R0;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   OrderedLocusNames=Sph21_4587 {ECO:0000313|EMBL:ADZ81102.1};
OS   Sphingobacterium sp. (strain 21).
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Sphingobacterium.
OX   NCBI_TaxID=743722 {ECO:0000313|EMBL:ADZ81102.1};
RN   [1] {ECO:0000313|EMBL:ADZ81102.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=21 {ECO:0000313|EMBL:ADZ81102.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Siebers A.K.,
RA   Allgaier M., Thelen M.P., Hugenholtz P., Woyke T.;
RT   "Complete sequence of Sphingobacterium sp. 21.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002584; ADZ81102.1; -; Genomic_DNA.
DR   AlphaFoldDB; F4C8R0; -.
DR   STRING; 743722.Sph21_4587; -.
DR   KEGG; shg:Sph21_4587; -.
DR   PATRIC; fig|743722.3.peg.4880; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_024620_1_0_10; -.
DR   OrthoDB; 7294637at2; -.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          60..353
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   381 AA;  42706 MW;  C02932AB5AAB5BB5 CRC64;
     MRENKFKYLY LLINFLIVGY GCVAGQHTSE RMAMDSSIVF TPNERYASTR IPALVMSKKG
     TLLAFCEGRI GSASDWSEMD LLMRRSKDGG RTWEAPIVIA PKKSGPTSNP TPIVDSKGTI
     HLLYQRDYAR AYYTFSTDDG ETWSPAMDIT ATFDAFKPAY DWKVLAPGPG HSIQLKNGRL
     LVPVWLSDPA KTVPHRSHAP SCIATIYSDD LGKTWKRGEI IAKNSAEFKN PSETMAIQLK
     DGRVMVNIRN TSEKHLRGVS YSKDGISGWS KPVFDEELFD PICMASIIRL SDRKKGILFL
     NPDSRDIPKH PRKNLTAKVS YDEGQTWPIS KLIHEGPSGY SDVAVGADGT VYCLFETNSG
     KDWNYNIVLK TFKLDWLTDN K
//