F4C5B7 (F4C5B7_SPHS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP-Rule MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP-Rule MF_01401
EC=1.8.4.11 HAMAP-Rule MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP-Rule MF_01401

Gene names

Name:	msrA HAMAP-Rule MF_01401
Ordered Locus Names:	Sph21_1655 EMBL ADZ78217.1

Organism

Sphingobacterium sp. (strain 21) [Complete proteome] [HAMAP] EMBL ADZ78217.1

Taxonomic identifier

743722 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Bacteroidetes/Chlorobi group › Bacteroidetes › Sphingobacteriia › Sphingobacteriales › Sphingobacteriaceae › Sphingobacterium

Protein attributes

Sequence length	172 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP-Rule MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP-Rule MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP-Rule MF_01401 EMBL ADZ78217.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cellular protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular_function	peptide-methionine (S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	9	1	By similarity HAMAP-Rule MF_01401

Sequences

	Sequence		Length	Mass (Da)
	F4C5B7 [UniParc]. Last modified June 28, 2011. Version 1. Checksum: 50FE7A81DFD74E5F	FASTA	172	19,672
	10 20 30 40 50 60 MKATFGGGCF WCTEVIFQQL DGVNSVLPGY MGGHKENPTY KEVCTGETGH AEVVQIDYDP 70 80 90 100 110 120 QKISYKKLLG IFFKTHDPTT LNRQGNDIGT QYRSAVFYHS PEQKFEAETL INKLTEEKIF 130 140 150 160 170 DDPIVTEVVE ARTFYEAEDY HHDYFNNNPD NPYCAAVIQP KLQKFLKSLE KA

References

[1]

"Complete sequence of Sphingobacterium sp. 21." Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Siebers A.K., Allgaier M. , Thelen M.P., Hugenholtz P., Woyke T. Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 21.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002584 Genomic DNA. Translation: ADZ78217.1.
RefSeq	YP_004316887.1. NC_015277.1.
3D structure databases
ProteinModelPortal	F4C5B7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADZ78217; ADZ78217; Sph21_1655.
GeneID	10347402.
KEGG	shg:Sph21_1655.
PATRIC	47237180. VBISphSp165585_1775.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K07304.
OMA	CTEAVFE.
Family and domain databases
Gene3D	3.30.1060.10. 1 hit.
HAMAP	MF_01401. MsrA.
InterPro	IPR002569. Met_Sox_Rdtase_MsrA. [Graphical view]
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. msrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F4C5B7_SPHS2

Accession

Primary (citable) accession number: F4C5B7

Entry history

Integrated into UniProtKB/TrEMBL:	June 28, 2011
Last sequence update:	June 28, 2011
Last modified:	April 3, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)