F4BLX1 (F4BLX1_CARS1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Xanthine phosphoribosyltransferase HAMAP-Rule MF_01184
Short name=XPRTase HAMAP-Rule MF_01184
EC=2.4.2.22 HAMAP-Rule MF_01184

Gene names

Name:	xpt HAMAP-Rule MF_01184 EMBL AEB30305.1
Ordered Locus Names:	CAR_c16470 EMBL AEB30305.1

Organism

Carnobacterium sp. (strain 17-4) [Complete proteome] [HAMAP] EMBL AEB30305.1

Taxonomic identifier

208596 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Carnobacteriaceae › Carnobacterium

Protein attributes

Sequence length	191 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis By similarity. HAMAP-Rule MF_01184
Catalytic activity	XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine. HAMAP-Rule MF_01184
Pathway	Purine metabolism; XMP biosynthesis via salvage pathway; XMP from xanthine: step 1/1. HAMAP-Rule MF_01184
Subunit structure	Homodimer By similarity. HAMAP-Rule MF_01184
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_01184.
Sequence similarities	Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily. HAMAP-Rule MF_01184

Ontologies

Keywords
Biological process	Purine salvage HAMAP-Rule MF_01184
Cellular component	Cytoplasm HAMAP-Rule MF_01184
Molecular function	Glycosyltransferase HAMAP-Rule MF_01184 EMBL AEB30305.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	XMP salvage Inferred from electronic annotation. Source: UniProtKB-UniPathway purine ribonucleoside salvage Inferred from electronic annotation. Source: HAMAP xanthine metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	xanthine phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	128 – 132	5	5-phospho-alpha-D-ribose 1-diphosphate binding By similarity HAMAP-Rule MF_01184
Sites
	Binding site	20	1	Xanthine; via amide nitrogen and carbonyl oxygen By similarity HAMAP-Rule MF_01184
	Binding site	27	1	Xanthine By similarity HAMAP-Rule MF_01184
	Binding site	156	1	Xanthine By similarity HAMAP-Rule MF_01184

Sequences

	Sequence		Length	Mass (Da)
	F4BLX1 [UniParc]. Last modified June 28, 2011. Version 1. Checksum: 609E952A6D8C619A	FASTA	191	21,237
	10 20 30 40 50 60 MKELEERILR DGNVLGGEVL KVDNFLNHQI DPKLMQSIGN EFAKHYANKG ITRIVTIESS 70 80 90 100 110 120 GIAPAVFAGL ALGVPVVFAR KKKSLTLTDD LYSTDVYSFT KKSTSTIVIS KKFLEKTDRI 130 140 150 160 170 180 LLIDDFLANG QAAKGLIKLC HEAQATVVGI GIVIEKSFQV GRQLLEEENY DVYSLARIRA 190 FEEGQVKFVE E

References

[1]	"Complete genome sequence of Carnobacterium sp. 17-4." Voget S., Klippel B., Daniel R., Antranikian G. J. Bacteriol. 193:3403-3404(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 17-4 EMBL AEB30305.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002563 Genomic DNA. Translation: AEB30305.1.
RefSeq	YP_004375321.1. NC_015391.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEB30305; AEB30305; CAR_c16470.
GeneID	10441767.
KEGG	crn:CAR_c16470.
PATRIC	54450820. VBICarSp108130_1619.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K03816.
Enzyme and pathway databases
BioCyc	CSP208596:GHHT-1647-MONOMER.
UniPathway	UPA00602; UER00658.
Family and domain databases
HAMAP	MF_01184. XPRTase.
InterPro	IPR000836. PRibTrfase_dom. IPR010079. Xanthine_PRibTrfase. [Graphical view]
Pfam	PF00156. Pribosyltran. 1 hit. [Graphical view]
TIGRFAMs	TIGR01744. XPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F4BLX1_CARS1

Accession

Primary (citable) accession number: F4BLX1

Entry history

Integrated into UniProtKB/TrEMBL:	June 28, 2011
Last sequence update:	June 28, 2011
Last modified:	April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)