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F4BBY5 (F4BBY5_FRACF) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length187 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. SAAS SAAS020634 HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. RuleBase RU004165 HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding77 – 804ATP By similarity HAMAP-Rule MF_00124

Sites

Active site781Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1351Zinc By similarity HAMAP-Rule MF_00124
Metal binding1371Zinc By similarity HAMAP-Rule MF_00124
Metal binding1771Zinc By similarity HAMAP-Rule MF_00124
Metal binding1801Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
F4BBY5 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: F041D168A8C5DADC

FASTA18721,242
        10         20         30         40         50         60 
MDAGKTLDLL KVAYNYEDRG RKPLVLTSAI DKRAGLNKVK SRIGIDQDAY SLTDRDNIFE 

        70         80         90        100        110        120 
FVENYNSSNK IDCVLIDEIH FFTQEQVWQL AEIVDELNIP VICYGLRTNY LGQPFETAAL 

       130        140        150        160        170        180 
LLAIADTLEE VKTICHCGKK ASFNMMVQNG KAIKQGNPIV VDDDSLKEID TKYVSVCRKH 


WKEGVYE 

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References

[1]"Common ancestry and novel genetic traits of Francisella novicida-like isolates from North America and Australia as revealed by comparative genomic analyses."
Siddaramappa S., Challacombe J.F., Petersen J.M., Pillai S., Hogg G., Kuske C.R.
Appl. Environ. Microbiol. 77:5110-5122(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Fx1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002557 Genomic DNA. Translation: AEE87487.1.
RefSeqYP_005826009.1. NC_017450.1.

3D structure databases

ProteinModelPortalF4BBY5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEE87487; AEE87487; FNFX1_1101.
GeneID12435904.
KEGGfcf:FNFX1_1101.
PATRIC54255778. VBIFraCf186347_1092.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00857.
OMARTICHCG.

Enzyme and pathway databases

BioCycFNOV984129:GLDD-1117-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF4BBY5_FRACF
AccessionPrimary (citable) accession number: F4BBY5
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: April 16, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)