SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

F4BBY5

- F4BBY5_FRACF

UniProt

F4BBY5 - F4BBY5_FRACF

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Thymidine kinase
Gene
tdk, FNFX1_1101
Organism
Francisella cf. novicida (strain Fx1)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei78 – 781Proton acceptor By similarityUniRule annotation
Metal bindingi135 – 1351Zinc By similarityUniRule annotation
Metal bindingi137 – 1371Zinc By similarityUniRule annotation
Metal bindingi177 – 1771Zinc By similarityUniRule annotation
Metal bindingi180 – 1801Zinc By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi77 – 804ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Enzyme and pathway databases

BioCyciFNOV984129:GLDD-1117-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:FNFX1_1101Imported
OrganismiFrancisella cf. novicida (strain Fx1)Imported
Taxonomic identifieri984129 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
ProteomesiUP000008302: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF4BBY5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00857.
OMAiELKTVCH.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

F4BBY5-1 [UniParc]FASTAAdd to Basket

« Hide

MDAGKTLDLL KVAYNYEDRG RKPLVLTSAI DKRAGLNKVK SRIGIDQDAY    50
SLTDRDNIFE FVENYNSSNK IDCVLIDEIH FFTQEQVWQL AEIVDELNIP 100
VICYGLRTNY LGQPFETAAL LLAIADTLEE VKTICHCGKK ASFNMMVQNG 150
KAIKQGNPIV VDDDSLKEID TKYVSVCRKH WKEGVYE 187
Length:187
Mass (Da):21,242
Last modified:June 28, 2011 - v1
Checksum:iF041D168A8C5DADC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002557 Genomic DNA. Translation: AEE87487.1.
RefSeqiYP_005826009.1. NC_017450.1.

Genome annotation databases

EnsemblBacteriaiAEE87487; AEE87487; FNFX1_1101.
GeneIDi12435904.
KEGGifcf:FNFX1_1101.
PATRICi54255778. VBIFraCf186347_1092.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002557 Genomic DNA. Translation: AEE87487.1 .
RefSeqi YP_005826009.1. NC_017450.1.

3D structure databases

ProteinModelPortali F4BBY5.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEE87487 ; AEE87487 ; FNFX1_1101 .
GeneIDi 12435904.
KEGGi fcf:FNFX1_1101.
PATRICi 54255778. VBIFraCf186347_1092.

Phylogenomic databases

KOi K00857.
OMAi ELKTVCH.

Enzyme and pathway databases

BioCyci FNOV984129:GLDD-1117-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Common ancestry and novel genetic traits of Francisella novicida-like isolates from North America and Australia as revealed by comparative genomic analyses."
    Siddaramappa S., Challacombe J.F., Petersen J.M., Pillai S., Hogg G., Kuske C.R.
    Appl. Environ. Microbiol. 77:5110-5122(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Fx1.

Entry informationi

Entry nameiF4BBY5_FRACF
AccessioniPrimary (citable) accession number: F4BBY5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: June 11, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3
Error
SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

500 Internal Server Error

The server was not able to handle your request.

If this error occurs repeatedly, please contact us and indicate the page you were trying to access.