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F4B9U1

- F4B9U1_ACIHW

UniProt

F4B9U1 - F4B9U1_ACIHW

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Acidianus hospitalis (strain W1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium.UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciAHOS933801:GHY6-2356-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:Ahos_2286Imported
OrganismiAcidianus hospitalis (strain W1)Imported
Taxonomic identifieri933801 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeAcidianus
ProteomesiUP000008458: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiKTMSTQH.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

F4B9U1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRKIPKTMST QHPDNARVPE WAKSEVIEGD DEVIEAYYSY MNLGIHEVMW
60 70 80 90 100
DAEGKDVDTH VVRKLLSSYA EYFKENIIGQ DVFLTYRLPN PRIEGAERKV
110 120 130 140 150
FAETMESIPV AYDLAEKFYG KKVIPVFEVI LPFTTDYQEL VSVAKYYEKA
160 170 180 190 200
VAGEEDIELF EGIHVRDLVG EIYPKRVEVI PLIEDKDSLL RIREIVGGYY
210 220 230 240 250
KVIKPTYMRV FIARSDPAMN YGMLTAVLLA KFALSTLYKM KNELGIEIFP
260 270 280 290 300
IIGVGSLPFR GHLSPKNYEN ALKEYKGVYT FTIQSAFKYD YDEKEVKEAI
310 320 330 340 350
QKINENKVEE PKVFDEHEEG LLKKIVENYV SSYQPIIEAL APAINFIALN
360 370 380 390 400
LPRRRARKLH ISLFGYARST GKVTLPRAIS FVGAMYTLGI PPEIIGLSSL
410 420 430 440 450
SKLSEEEWDF LKENYIMFNH DLNESGKYVN LDTLEYLKEI WNIDDEVINK
460 470 480 490 500
IKEDIKFAES IGIKIGGDDY ESKKHVLLSS LALLACKEKK YDEMKEYIKE

MALIRKSLG
Length:509
Mass (Da):58,564
Last modified:June 28, 2011 - v1
Checksum:i899109E5858C617A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002535 Genomic DNA. Translation: AEE95157.1.
RefSeqiYP_004459455.1. NC_015518.1.

Genome annotation databases

EnsemblBacteriaiAEE95157; AEE95157; Ahos_2286.
GeneIDi10601793.
KEGGiaho:Ahos_2286.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002535 Genomic DNA. Translation: AEE95157.1 .
RefSeqi YP_004459455.1. NC_015518.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEE95157 ; AEE95157 ; Ahos_2286 .
GeneIDi 10601793.
KEGGi aho:Ahos_2286.

Phylogenomic databases

KOi K01595.
OMAi KTMSTQH.

Enzyme and pathway databases

BioCyci AHOS933801:GHY6-2356-MONOMER.

Family and domain databases

HAMAPi MF_01904. PEPcase_type2.
InterProi IPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF14010. PEPcase_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF006677. UCP006677. 1 hit.
SUPFAMi SSF51621. SSF51621. 1 hit.
TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genomic analysis of Acidianus hospitalis W1 a host for studying crenarchaeal virus and plasmid life cycles."
    You X.Y., Liu C., Wang S.Y., Jiang C.Y., Shah S.A., Prangishvili D., She Q., Liu S.J., Garrett R.A.
    Extremophiles 15:487-497(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: W1Imported.
  2. "Genomic analyses of Acidianus hospitalis W1 a host for studying crenarchaeal virus and plasmid life cycles."
    You X.Y., Liu C., Wang S.Y., Jiang C.Y., Shah S.A., Prangishvili D., Liu S.J., Garrett R.A.
    Extremophiles 0:0-0(2011)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: W1.

Entry informationi

Entry nameiF4B9U1_ACIHW
AccessioniPrimary (citable) accession number: F4B9U1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: October 29, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3