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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Acidianus hospitalis (strain W1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciAHOS933801:GHY6-2356-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:Ahos_2286Imported
OrganismiAcidianus hospitalis (strain W1)Imported
Taxonomic identifieri933801 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeAcidianus
ProteomesiUP000008458 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi933801.Ahos_2286.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiQAYREET.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

F4B9U1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKIPKTMST QHPDNARVPE WAKSEVIEGD DEVIEAYYSY MNLGIHEVMW
60 70 80 90 100
DAEGKDVDTH VVRKLLSSYA EYFKENIIGQ DVFLTYRLPN PRIEGAERKV
110 120 130 140 150
FAETMESIPV AYDLAEKFYG KKVIPVFEVI LPFTTDYQEL VSVAKYYEKA
160 170 180 190 200
VAGEEDIELF EGIHVRDLVG EIYPKRVEVI PLIEDKDSLL RIREIVGGYY
210 220 230 240 250
KVIKPTYMRV FIARSDPAMN YGMLTAVLLA KFALSTLYKM KNELGIEIFP
260 270 280 290 300
IIGVGSLPFR GHLSPKNYEN ALKEYKGVYT FTIQSAFKYD YDEKEVKEAI
310 320 330 340 350
QKINENKVEE PKVFDEHEEG LLKKIVENYV SSYQPIIEAL APAINFIALN
360 370 380 390 400
LPRRRARKLH ISLFGYARST GKVTLPRAIS FVGAMYTLGI PPEIIGLSSL
410 420 430 440 450
SKLSEEEWDF LKENYIMFNH DLNESGKYVN LDTLEYLKEI WNIDDEVINK
460 470 480 490 500
IKEDIKFAES IGIKIGGDDY ESKKHVLLSS LALLACKEKK YDEMKEYIKE

MALIRKSLG
Length:509
Mass (Da):58,564
Last modified:June 28, 2011 - v1
Checksum:i899109E5858C617A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002535 Genomic DNA. Translation: AEE95157.1.
RefSeqiWP_013777072.1. NC_015518.1.
YP_004459455.1. NC_015518.1.

Genome annotation databases

EnsemblBacteriaiAEE95157; AEE95157; Ahos_2286.
GeneIDi10601793.
KEGGiaho:Ahos_2286.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002535 Genomic DNA. Translation: AEE95157.1.
RefSeqiWP_013777072.1. NC_015518.1.
YP_004459455.1. NC_015518.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi933801.Ahos_2286.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEE95157; AEE95157; Ahos_2286.
GeneIDi10601793.
KEGGiaho:Ahos_2286.

Phylogenomic databases

KOiK01595.
OMAiQAYREET.

Enzyme and pathway databases

BioCyciAHOS933801:GHY6-2356-MONOMER.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genomic analysis of Acidianus hospitalis W1 a host for studying crenarchaeal virus and plasmid life cycles."
    You X.Y., Liu C., Wang S.Y., Jiang C.Y., Shah S.A., Prangishvili D., She Q., Liu S.J., Garrett R.A.
    Extremophiles 15:487-497(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: W1Imported.
  2. "Genomic analyses of Acidianus hospitalis W1 a host for studying crenarchaeal virus and plasmid life cycles."
    You X.Y., Liu C., Wang S.Y., Jiang C.Y., Shah S.A., Prangishvili D., Liu S.J., Garrett R.A.
    Extremophiles 0:0-0(2011)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: W1.

Entry informationi

Entry nameiF4B9U1_ACIHW
AccessioniPrimary (citable) accession number: F4B9U1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: June 24, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.