ID   F4AVH1_DOKS4            Unreviewed;       541 AA.
AC   F4AVH1;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE            EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN   OrderedLocusNames=Krodi_1004 {ECO:0000313|EMBL:AEE18988.1};
OS   Dokdonia sp. (strain 4H-3-7-5) (Krokinobacter sp. (strain 4H-3-7-5)).
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Dokdonia.
OX   NCBI_TaxID=983548 {ECO:0000313|EMBL:AEE18988.1, ECO:0000313|Proteomes:UP000008290};
RN   [1] {ECO:0000313|EMBL:AEE18988.1, ECO:0000313|Proteomes:UP000008290}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=4H-3-7-5 {ECO:0000313|EMBL:AEE18988.1,
RC   ECO:0000313|Proteomes:UP000008290};
RX   PubMed=21725025; DOI=10.1128/JB.05518-11;
RA   Klippel B., Lochner A., Bruce D.C., Walston Davenport K., Detter C.,
RA   Goodwin L.A., Han J., Han S., Hauser L., Land M.L., Nolan M.,
RA   Ovchinnikova G., Pennacchio L., Pitluck S., Tapia R., Woyke T.,
RA   Wiebusch S., Basner A., Abe F., Horikoshi K., Keller M., Antranikian G.;
RT   "Complete genome sequences of Krokinobacter sp. strain 4H-3-7-5 and
RT   Lacinutrix sp. strain 5H-3-7-4, polysaccharide-degrading members of the
RT   family Flavobacteriaceae.";
RL   J. Bacteriol. 193:4545-4546(2011).
RN   [2] {ECO:0000313|Proteomes:UP000008290}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=4H-3-7-5 {ECO:0000313|Proteomes:UP000008290};
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Piela B., Lochner A.,
RA   Antranikian F.I., Woyke T.;
RT   "Complete sequence of Krokinobacter diaphorus 4H-3-7-5.";
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=4H-3-7-5;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Piela B., Lochner A.,
RA   Antranikian F.I., Woyke T.;
RT   "Complete sequence of Krokinobacter sp. 4H-3-7-5.";
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC         (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC         diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR   EMBL; CP002528; AEE18988.1; -; Genomic_DNA.
DR   RefSeq; WP_013750496.1; NC_015496.1.
DR   AlphaFoldDB; F4AVH1; -.
DR   STRING; 983548.Krodi_1004; -.
DR   KEGG; kdi:Krodi_1004; -.
DR   eggNOG; COG1793; Bacteria.
DR   HOGENOM; CLU_005138_6_2_10; -.
DR   OrthoDB; 9767858at2; -.
DR   Proteomes; UP000008290; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR   CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR   Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR   PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR   PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   SUPFAM; SSF117018; ATP-dependent DNA ligase DNA-binding domain; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:AEE18988.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          303..435
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50160"
SQ   SEQUENCE   541 AA;  62734 MW;  EDEA97A40524DF62 CRC64;
     MKLFAALIKT LDSTNKTNEK VKALAHYFRE ASDKDKVWTI AILSHRRPPR PVNTTLLREW
     ASELSNIPLW LFEESYHIVG DLAETIALVV PAATASSEKS LTQFLEEMIS LKRKTDEEKK
     EYLFDNWANL NYYERFVFTK LITGGFRIGV SQKLMTRALS QATDIEEDVL AYKLMGDWKP
     QTVTFHDLVI EEDASQEFSR PYPFYLAYAV EDEPSALGDV TDFLAEHKWD GIRSQTIFRN
     GEIFIWSRGE ELVTDKYPEL EILKEHIPDG TVIDGELLPF YDGQIGTFND LQARIGRKTV
     SKKMLKEVPV IIKAYDILEW EGKDLRETAF AKRRTILESL YRNITDKELP IGISETMEFD
     SWEAMAQERD RSREMRSEGL MIKRKDSPYR VGRKKGDWWK WKVDPLTIDA VLTYAMRGHG
     RRSNLFTDYT FGLWNEDKTE LVTFAKAYSG LTDAEFRKVD NWIKKNTLER FGPVRSVTPH
     HVFEIAFEGI ALSKRHKSGI ATRFPRMLRW RHDKQIEDAN TLEDLKGMIP SAAKESLPPT
     K
//