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Protein

Superoxide dismutase [Cu-Zn]

Gene

Glaag_2446

Organism
Glaciecola sp. (strain 4H-3-7+YE-5)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciGSP983545:GH3Q-2502-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Glaag_2446Imported
OrganismiGlaciecola sp. (strain 4H-3-7+YE-5)Imported
Taxonomic identifieri983545 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeGlaciecola
ProteomesiUP000006544: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424 PotentialImportedAdd
BLAST
Chaini25 – 180156 PotentialImportedPRO_5000737589Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliF4ATC4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

KOiK04565.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

F4ATC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKFLLPILA GSISLALSTA SFAGDSEDGK KIVMNDLKTG ESIGSVMVRD
60 70 80 90 100
YDDDGVVFTP ELSGLTPGMH GFHIHENGDC SSAMKDGKNV LGGAAGGHFD
110 120 130 140 150
PEDTGKHSVP WSEKGHEGDL PTLFVDNNGK ASKPIFAPEL ELDDIEGRAL
160 170 180
MIHAGGDNYS DSPEKLGGGG SRVACGVIGD
Length:180
Mass (Da):18,729
Last modified:June 28, 2011 - v1
Checksum:i09035436280619EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002526 Genomic DNA. Translation: AEE23388.1.
RefSeqiYP_004434656.1. NC_015497.1.

Genome annotation databases

EnsemblBacteriaiAEE23388; AEE23388; Glaag_2446.
GeneIDi10572593.
KEGGigag:Glaag_2446.
PATRICi54578617. VBIGlaSp182133_2599.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002526 Genomic DNA. Translation: AEE23388.1.
RefSeqiYP_004434656.1. NC_015497.1.

3D structure databases

ProteinModelPortaliF4ATC4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEE23388; AEE23388; Glaag_2446.
GeneIDi10572593.
KEGGigag:Glaag_2446.
PATRICi54578617. VBIGlaSp182133_2599.

Phylogenomic databases

KOiK04565.

Enzyme and pathway databases

BioCyciGSP983545:GH3Q-2502-MONOMER.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 4H-3-7+YE-5Imported.
  2. "Complete sequence of chromosome of Glaciecola sp. 4H-3-7+YE-5."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Piela B., Lochner A., Antranikian F.I., Woyke T.
    Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 4H-3-7+YE-5.

Entry informationi

Entry nameiF4ATC4_GLAS4
AccessioniPrimary (citable) accession number: F4ATC4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: January 7, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.