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F4AE04

- F4AE04_LACJH

UniProt

F4AE04 - F4AE04_LACJH

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, LJP_0907c
Organism
Lactobacillus johnsonii DPC 6026
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarityUniRule annotation
Active sitei575 – 5751 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotations

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciLJOH909954:GLFA-921-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:LJP_0907cImported
OrganismiLactobacillus johnsonii DPC 6026Imported
Taxonomic identifieri909954 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000006836: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F4AE04-1 [UniParc]FASTAAdd to Basket

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MSIKKLENSS DHAMVAEEVK ILTNLLNEST RQLSGDVIFN KIQDLIKISA    50
QKDYDALEKQ IASLTNQEMI VVARYFATLP LLVNISEDVE LASEVNLLNN 100
TDQDYLGKLE DTIDLVSQKE NASEILKHVN VVPVLTAHPT QVQRKTVLEL 150
TDQIHGLLRS YREVKNGTIN QAEWTEKLRA YIEILMQTDI IRSHKLQVSN 200
EITNVLAYYP KALIPAITKF TARYQELAKK HNLNLSGATP ITMGMWIGGD 250
RDGNPYVTAE TLKLSATLQS QVIFEYYIKQ LNKLYRTISM STSYMKPSSA 300
VEKLSELSND DSPFRTNEPY RRAFYYIESR LLHTEYTLLG TADKNSFVKK 350
RDLENLDKIP VYKNPQDFKA DLITIKESLE EDHDQAVVRS FFTELLEAID 400
IFGFHLATID MRQDSSVNEA CVAELLKSAG ICDDYSDLPE KDKVKVLLNE 450
LNNDPRNLHA NNKPKSELLQ KELNIYKTAR QLKDCIGEDV IKQHIISHTE 500
SVSDLLEQAI MLKEYDLLNN QGARIQVVPL FETVEDLENS REIMKEFLNL 550
DIVKRWLASQ NNYQEIMLGY SDSNKDGGYL ASCWNLYKAQ KDLTAMGKKL 600
GVNITFMHGR GGTVGRGGGP SYEAITAQPF GSINDRIRMT EQGEIIQNKY 650
GNQDTAYYNL EMLASATIDR IVSKQIVSED NIGGFRSSMD EIVLDSNKVY 700
RKLVFETPAF LDYFLQATPI KQISNLNIGS RPAARKKITD FSGLRAIPWV 750
FSWSQSRIMF PGWYGVGSAF KHFIDANPNN LHTLKKMYQG WPFFHSLLSN 800
VDMVLSKSNM DIAKQYADLC EDEDTKKVFD TIYQEWKLTK EVILQIEGNK 850
ELLADNPSLK MSLNYRMPYF NILNYIQIEM IKRDRVDEIA GVYESILPIT 900
INGVTSGLRN SG 912
Length:912
Mass (Da):103,892
Last modified:June 28, 2011 - v1
Checksum:i50B1B1B483DCC84E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002464 Genomic DNA. Translation: AEB93233.1.
RefSeqiYP_005862183.1. NC_017477.1.

Genome annotation databases

EnsemblBacteriaiAEB93233; AEB93233; LJP_0907c.
GeneIDi12470579.
KEGGiljh:LJP_0907c.
PATRICi54202737. VBILacJoh171132_0948.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002464 Genomic DNA. Translation: AEB93233.1 .
RefSeqi YP_005862183.1. NC_017477.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEB93233 ; AEB93233 ; LJP_0907c .
GeneIDi 12470579.
KEGGi ljh:LJP_0907c.
PATRICi 54202737. VBILacJoh171132_0948.

Phylogenomic databases

KOi K01595.

Enzyme and pathway databases

BioCyci LJOH909954:GLFA-921-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Host Specific Diversity in Lactobacillus johnsonii as Evidenced by a Major Chromosomal Inversion and Phage Resistance Mechanisms."
    Guinane C.M., Kent R.M., Norberg S., Hill C., Fitzgerald G.F., Stanton C., Ross R.P.
    PLoS ONE 6:E18740-E18740(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DPC 6026Imported.

Entry informationi

Entry nameiF4AE04_LACJH
AccessioniPrimary (citable) accession number: F4AE04
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 3, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi