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F4A740

- F4A740_CLOBO

UniProt

F4A740 - F4A740_CLOBO

Protein

Thymidine kinase

Gene

CbC4_2284

Organism
Clostridium botulinum BKT015925
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (28 Jun 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. thymidine kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCBOT929506:GHKW-2349-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    ORF Names:CbC4_2284Imported
    OrganismiClostridium botulinum BKT015925Imported
    Taxonomic identifieri929506 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000007806: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    KOiK00857.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F4A740-1 [UniParc]FASTAAdd to Basket

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    MNSGKSTNLM QVAHNYEERG MKVIIIKPKR DSKGGDKVIS RLGVTRKVDM    50
    LLDVNENAYE RVQQICNEEG TLNCILVDEV QFLKKEQIDQ LFEIAVKLNI 100
    PTICYGLRTD FQMNGFEGSM RLLLLAHSIE ELKTICSCGK KASLNGRKIN 150
    GKFVFQGEQI AIDKEDNVEY ESLCPKCYLE YRDGLKR 187
    Length:187
    Mass (Da):21,345
    Last modified:June 28, 2011 - v1
    Checksum:iAF80C2692CACDB5E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002410 Genomic DNA. Translation: AEB76949.1.
    RefSeqiWP_013726456.1. NC_015425.1.
    YP_004396946.1. NC_015425.1.

    Genome annotation databases

    EnsemblBacteriaiAEB76949; AEB76949; CbC4_2284.
    GeneIDi10465241.
    KEGGicbn:CbC4_2284.
    PATRICi54459962. VBICloBot178872_2596.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002410 Genomic DNA. Translation: AEB76949.1 .
    RefSeqi WP_013726456.1. NC_015425.1.
    YP_004396946.1. NC_015425.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEB76949 ; AEB76949 ; CbC4_2284 .
    GeneIDi 10465241.
    KEGGi cbn:CbC4_2284.
    PATRICi 54459962. VBICloBot178872_2596.

    Phylogenomic databases

    KOi K00857.

    Enzyme and pathway databases

    BioCyci CBOT929506:GHKW-2349-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Clostridium botulinum group III: a group with dual identity shaped by plasmids, phages and mobile elements."
      Skarin H., Hafstrom T., Westerberg J., Segerman B.
      BMC Genomics 12:185-185(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BKT015925Imported.

    Entry informationi

    Entry nameiF4A740_CLOBO
    AccessioniPrimary (citable) accession number: F4A740
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3