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Protein

Guanylate kinase

Gene

gmk

Organism
Mahella australiensis (strain DSM 15567 / CIP 107919 / 50-1 BON)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotationSAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 18ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.8UniRule annotationSAAS annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:Mahau_0979Imported
OrganismiMahella australiensis (strain DSM 15567 / CIP 107919 / 50-1 BON)Imported
Taxonomic identifieri697281 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacterales Family IV. Incertae SedisMahella
Proteomesi
  • UP000008457 Componenti: Chromosome

Subcellular locationi

F4A2D0:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi697281.Mahau_0979.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 182Guanylate kinase-likeInterPro annotationAdd BLAST179

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4108UHA. Bacteria.
COG0194. LUCA.
KOiK00942.
OMAiYGTLKSE.
OrthoDBiPOG091H01Q4.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F4A2D0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQGLLIVIS GPSGAGKGTI CRALRRFNHN VELSISATTR APRRGEREGV
60 70 80 90 100
NYFFKTVDEF KRMIEDGEFL EYAEVYGNYY GTPKSYVRER LMEGKDVILE
110 120 130 140 150
IDIQGALSIK EKFDDAVFIF ILPPSMEELK RRIVKRGTES EEELLKRFNS
160 170 180 190 200
SYKELNFINR YNYVVINDVV EAAARKIDAI ITAEKCRVER NKDLYINYLE

GLEK
Length:204
Mass (Da):23,612
Last modified:June 28, 2011 - v1
Checksum:iEF0031F73D9F19E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002360 Genomic DNA. Translation: AEE96177.1.
RefSeqiWP_013780607.1. NC_015520.1.

Genome annotation databases

EnsemblBacteriaiAEE96177; AEE96177; Mahau_0979.
KEGGimas:Mahau_0979.

Similar proteinsi

Entry informationi

Entry nameiF4A2D0_MAHA5
AccessioniPrimary (citable) accession number: F4A2D0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 27, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported