Skip Header

Contribute Send feedback
Read comments (?) or add your own

F3Y820 (F3Y820_MELPT) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Protein translocase subunit SecY HAMAP-Rule MF_01465
Gene names
Name:secY HAMAP-Rule MF_01465
Ordered Locus Names:MPTP_0149 EMBL BAK20648.1
OrganismMelissococcus plutonius (strain ATCC 35311 / CIP 104052 / LMG 20360 / NCIMB 702443) [Complete proteome] [HAMAP] EMBL BAK20648.1
Taxonomic identifier940190 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Enterococcaceae › Melissococcus ›

Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently By similarity. HAMAP-Rule MF_01465

Subunit structure

Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA By similarity. HAMAP-Rule MF_01465

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01465.

Sequence similarities

Belongs to the SecY/SEC61-alpha family. RuleBase RU004349 HAMAP-Rule MF_01465

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane19 – 3921Helical; By similarity HAMAP-Rule MF_01465
Transmembrane67 – 8721Helical; By similarity HAMAP-Rule MF_01465
Transmembrane115 – 13521Helical; By similarity HAMAP-Rule MF_01465
Transmembrane146 – 16621Helical; By similarity HAMAP-Rule MF_01465
Transmembrane175 – 19521Helical; By similarity HAMAP-Rule MF_01465
Transmembrane215 – 23521Helical; By similarity HAMAP-Rule MF_01465
Transmembrane265 – 28521Helical; By similarity HAMAP-Rule MF_01465
Transmembrane309 – 32921Helical; By similarity HAMAP-Rule MF_01465
Transmembrane369 – 38921Helical; By similarity HAMAP-Rule MF_01465
Transmembrane391 – 41121Helical; By similarity HAMAP-Rule MF_01465

Sequences

Sequence LengthMass (Da)Tools
F3Y820 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: 93BBA71D99ED6843

FASTA43147,373
        10         20         30         40         50         60 
MFRLLNNAFK VKDIRSKLFF TLFVLFVFRL GTHITVPGVD AKGLSDLSNL PFLNMLNMVS 

        70         80         90        100        110        120 
GSAIQNFSIF SMGVSPYITA SIIIQLLQMD IVPKFVEWSK QGEVGRKKLN QATRYLTIVL 

       130        140        150        160        170        180 
GIAQSMGITA GFNSLSQTGI VKHPSFGTFV MIAVILTSGT MFVTWLGEQI TEKGIGNGVS 

       190        200        210        220        230        240 
MIIFAGIISR LPDSIKSLVD DYFINIESSK IWQSVIFMLI LIIAILVIVT FVTFFQQAER 

       250        260        270        280        290        300 
KIPIQYTKRM TGAPTSSYLP LKVNAAGVIP VIFASSLIAT PNALLQAFTK YSGEGWYDVM 

       310        320        330        340        350        360 
TKIFSYNTVP GATVYTVLIV AFTFFYAFVQ VNPEKLAENL QKQGSYIPSV RPGKGTESYV 

       370        380        390        400        410        420 
SSVLMRLSVV GAIFLGLVAL LPIIAQMIWK LPQSIGLGGT SLLIVIGVAL ETAKQLEGLM 

       430 
LKRRYVGFIN K

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Melissococcus plutonius ATCC 35311."
Okumura K., Arai R., Okura M., Kirikae T., Takamatsu D., Osaki M., Miyoshi-Akiyama T.
J. Bacteriol. 193:4029-4030(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35311 / CIP 104052 / LMG 20360 / NCIMB 702443.
[2]"Whole genome sequence of Melissococcus plutonius ATCC 35311."
Okumura K., Arai R., Osaki M., Okura M., Kirikae T., Takamatsu D., Akiyama T.
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: ATCC 35311.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP012200 Genomic DNA. Translation: BAK20648.1.
RefSeqYP_004455457.1. NC_015516.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAK20648; BAK20648; MPTP_0149.
GeneID10594975.
KEGGmps:MPTP_0149.
PATRIC54618957. VBIMelPlu182073_0150.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK03076.

Enzyme and pathway databases

BioCycMPLU940190:GH20-299-MONOMER.

Family and domain databases

Gene3D1.10.3370.10. 1 hit.
HAMAPMF_01465. SecY.
InterProIPR026593. SecY.
IPR002208. SecY/SEC61-alpha.
IPR023201. SecY_su_dom.
[Graphical view]
PANTHERPTHR10906. PTHR10906. 1 hit.
PfamPF00344. SecY. 1 hit.
[Graphical view]
PIRSFPIRSF004557. SecY. 1 hit.
SUPFAMSSF103491. SecY. 1 hit.
TIGRFAMsTIGR00967. 3a0501s007. 1 hit.
PROSITEPS00755. SECY_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF3Y820_MELPT
AccessionPrimary (citable) accession number: F3Y820
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: April 3, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info