F2Z4A9 (F2Z4A9_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Probable global transcription activator SNF2L2 Ensembl ENSMUSP00000025862

Gene names

Name:

Smarca2 Ensembl ENSMUSP00000025862 MGI 99603

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000025862

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1583 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000025862

Ontologies

Keywords
Domain	Bromodomain SAAS SAAS018359
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	aortic smooth muscle cell differentiation Inferred from mutant phenotype PubMed 19342595. Source: MGI negative regulation of cell growth Inferred from electronic annotation. Source: Compara negative regulation of cell proliferation Inferred from mutant phenotype PubMed 9843504. Source: MGI negative regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: Compara nucleosome assembly Traceable author statement PubMed 11163203. Source: MGI positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: GOC
Cellular_component	SWI/SNF complex Traceable author statement PubMed 11163203PubMed 11318604. Source: MGI WINAC complex Inferred from electronic annotation. Source: Compara intermediate filament cytoskeleton Inferred from electronic annotation. Source: Compara nuclear chromatin Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro RNA polymerase II transcription coactivator activity Inferred from electronic annotation. Source: Compara helicase activity Inferred from electronic annotation. Source: InterPro transcription regulatory region DNA binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F2Z4A9 [UniParc]. Last modified May 31, 2011. Version 1. Checksum: 11584802644C363E	FASTA	1,583	180,722
	10 20 30 40 50 60 MSTPTDPAAM PHPGPSPGPG PSPGPILGPS PGPGPSPGSV HSMMGPSPGP PSVSHPLSTM 70 80 90 100 110 120 GSADFPQEGM HQLHKPMDGI HDKGIVEDVH CGSMKGTSMR PPHPGMGPPQ SPMDQHSQGY 130 140 150 160 170 180 MSPHPSPLGA PEHVSSPISG GGPTPPQMPP SQPGALIPGD PQAMNQPNRG PSPFSPVQLH 190 200 210 220 230 240 QLRAQILAYK MLARGQPLPE TLQLAVQGKR TLPGMQQQQQ QQQQQQQQQQ QQQQQQQQQQ 250 260 270 280 290 300 QPQQPQQQAQ AQPQQQQQQQ QQPALVSYNR PSGPGQELLL SGQSAPQKLS APAPSGRPSP 310 320 330 340 350 360 APQAAVQPTA TAVPGPSVQQ PAPGQPSPVL QLQQKQSRIS PIQKPQGLDP VEILQEREYR 370 380 390 400 410 420 LQARIAHRIQ ELESLPGSLP PDLRTKATVE LKALRLLNFQ RQLRQEVVAC MRRDTTLETA 430 440 450 460 470 480 LNSKAYKRSK RQTLREARMT EKLEKQQKIE QERKRRQKHQ EYLNSILQHA KDFKEYHRSV 490 500 510 520 530 540 AGKIQKLSKA VATWHANTER EQKKETERIE KERMRRLMAE DEEGYRKLID QKKDRRLAYL 550 560 570 580 590 600 LQQTDEYVAN LTNLVWEHKQ AQAAKEKKKR RRRKKKAEEN AEGGEPALGP DGEPIDESSQ 610 620 630 640 650 660 MSDLPVKVTH TETGKVLFGP EAPKASQLDA WLEMNPGYEV APRSDSEESE SDYEEEDEEE 670 680 690 700 710 720 ESSRQETEEK ILLDPNSEEV SEKDAKQIIE TAKQDVDDEY SMQYSARGSQ SYYTVAHAIS 730 740 750 760 770 780 ERVEKQSALL INGTLKHYQL QGLEWMVSLY NNNLNGILAD EMGLGKTIQT IALITYLMEH 790 800 810 820 830 840 KRLNGPYLII VPLSTLSNWT YEFDKWAPSV VKISYKGTPA MRRSLVPQLR SGKFNVLLTT 850 860 870 880 890 900 YEYIIKDKHI LAKIRWKYMI VDEGHRMKNH HCKLTQVLNT HYVAPRRILL TGTPLQNKLP 910 920 930 940 950 960 ELWALLNFLL PTIFKSCSTF EQWFNAPFAM TGERVDLNEE ETILIIRRLH KVLRPFLLRR 970 980 990 1000 1010 1020 LKKEVESQLP EKVEYVIKCD MSALQKILYR HMQAKGILLT DGSEKDKKGK GGAKTLMNTI 1030 1040 1050 1060 1070 1080 MQLRKICNHP YMFQHIEESF AEHLGYSNGV INGAELYRAS GKFELLDRIL PKLRATNHRV 1090 1100 1110 1120 1130 1140 LLFCQMTSLM TIMEDYFAFR NFLYLRLDGT TKSEDRAALL KKFNEPGSQY FIFLLSTRAG 1150 1160 1170 1180 1190 1200 GLGLNLQAAD TVVIFDSDWN PHQDLQAQDR AHRIGQQNEV RVLRLCTVNS VEEKILAAAK 1210 1220 1230 1240 1250 1260 YKLNVDQKVI QAGMFDQKSS SHERRAFLQA ILEHEEENEE EDEVPDDETL NQMIARREEE 1270 1280 1290 1300 1310 1320 FDLFMRMDMD RRREDARNPK RKPRLMEEDE LPSWIIKDDA EVERLTCEEE EEKIFGRGSR 1330 1340 1350 1360 1370 1380 QRRDVDYSDA LTEKQWLRAI EDGNLEEMEE EVRLKKRKRR RNVDKDPVKE DVEKAKKRRG 1390 1400 1410 1420 1430 1440 RPPAEKLSPN PPKLTKQMNA IIDTVINYKD SSGRQLSEVF IQLPSRKDLP EYYELIRKPV 1450 1460 1470 1480 1490 1500 DFKKIKERIR NHKYRSLGDL EKDVMLLCHN AQTFNLEGSQ IYEDSIVLQS VFKSARQKIA 1510 1520 1530 1540 1550 1560 KEEESEEESN EEEEEDDEEE SESEAKSVKV KIKLNKKEEK GRDTGKGKKR PNRGKAKPVV 1570 1580 SDFDSDEEQE ENEQSEASGT DNE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000025862.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000025862.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC118249 Genomic DNA. No translation available. AC118472 Genomic DNA. No translation available.
IPI	IPI00469712.
RefSeq	NP_035546.2. NM_011416.2.
UniGene	Mm.313303.
3D structure databases
ProteinModelPortal	F2Z4A9.
SMR	F2Z4A9. Positions 1389-1497.
ModBase	Search...
Proteomic databases
PRIDE	F2Z4A9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000025862; ENSMUSP00000025862; ENSMUSG00000024921.
GeneID	67155.
KEGG	mmu:67155.
Organism-specific databases
CTD	6595.
MGI	MGI:99603. Smarca2.
Phylogenomic databases
GeneTree	ENSGT00550000074659.
KO	K11647.
Gene expression databases
ArrayExpress	F2Z4A9.
Bgee	F2Z4A9.
Family and domain databases
Gene3D	1.20.920.10. 1 hit.
InterPro	IPR006576. BRK_domain. IPR001487. Bromodomain. IPR018359. Bromodomain_CS. IPR014978. Gln-Leu-Gln_QLQ. IPR013999. HAS_subgr. IPR014012. Helicase/SANT-assoc_DNA-bd. IPR014001. Helicase_ATP-bd. IPR001650. Helicase_C. IPR006562. HSA. IPR000330. SNF2_N. [Graphical view]
Pfam	PF07533. BRK. 1 hit. PF00439. Bromodomain. 1 hit. PF00271. Helicase_C. 1 hit. PF07529. HSA. 1 hit. PF00176. SNF2_N. 1 hit. [Graphical view]
PRINTS	PR00503. BROMODOMAIN.
SMART	SM00592. BRK. 1 hit. SM00297. BROMO. 1 hit. SM00487. DEXDc. 1 hit. SM00490. HELICc. 1 hit. SM00573. HSA. 1 hit. SM00951. QLQ. 1 hit. [Graphical view]
SUPFAM	SSF47370. Bromodomain. 1 hit.
PROSITE	PS00633. BROMODOMAIN_1. 1 hit. PS50014. BROMODOMAIN_2. 1 hit. PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. PS51204. HSA. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	SMARCA2. mouse.
NextBio	323746.
SOURCE	Search...

Entry information

Entry name

F2Z4A9_MOUSE

Accession

Primary (citable) accession number: F2Z4A9

Entry history

Integrated into UniProtKB/TrEMBL:	May 31, 2011
Last sequence update:	May 31, 2011
Last modified:	April 3, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)