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F2Z488

- F2Z488_MOUSE

UniProt

F2Z488 - F2Z488_MOUSE

Protein
Submitted name:

Glutamate receptor 3

Gene

Gria3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 23 (01 Oct 2014)
      Sequence version 1 (31 May 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity Source: RefGenome
    2. extracellular-glutamate-gated ion channel activity Source: RefGenome
    3. protein binding Source: MGI

    GO - Biological processi

    1. ionotropic glutamate receptor signaling pathway Source: RefGenome
    2. ion transmembrane transport Source: RefGenome
    3. synaptic transmission, glutamatergic Source: RefGenome

    Keywords - Molecular functioni

    Ion channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation

    Keywords - Biological processi

    Ion transport, Transport

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Glutamate receptor 3Imported
    Gene namesi
    Name:Gria3Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome X

    Organism-specific databases

    MGIiMGI:95810. Gria3.

    Subcellular locationi

    GO - Cellular componenti

    1. alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Source: MGI
    2. cell junction Source: UniProtKB-KW
    3. dendrite Source: RefGenome
    4. membrane Source: MGI
    5. postsynaptic membrane Source: MGI

    Keywords - Cellular componenti

    Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

    PTM / Processingi

    Proteomic databases

    PRIDEiF2Z488.

    Expressioni

    Gene expression databases

    ArrayExpressiF2Z488.
    BgeeiF2Z488.

    Structurei

    3D structure databases

    ProteinModelPortaliF2Z488.
    SMRiF2Z488. Positions 26-815.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000115362.

    Family and domain databases

    InterProiIPR001828. ANF_lig-bd_rcpt.
    IPR019594. Glu_rcpt_Glu/Gly-bd.
    IPR001320. Iontro_glu_rcpt.
    IPR001508. NMDA_rcpt.
    IPR028082. Peripla_BP_I.
    [Graphical view]
    PfamiPF01094. ANF_receptor. 1 hit.
    PF00060. Lig_chan. 1 hit.
    PF10613. Lig_chan-Glu_bd. 1 hit.
    [Graphical view]
    PRINTSiPR00177. NMDARECEPTOR.
    SMARTiSM00918. Lig_chan-Glu_bd. 1 hit.
    SM00079. PBPe. 1 hit.
    [Graphical view]
    SUPFAMiSSF53822. SSF53822. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F2Z488-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGQSVLRAVF FLVLGLLGHS HGGFPNTISI GGLFMRNTVQ EHSAFRFAVQ    50
    LYNTNQNTTE KPFHLNYHVD HLDSSNSFSV TNAFCSQFSR GVYAIFGFYD 100
    QMSMNTLTSF CGALHTSFVT PSFPTDADVQ FVIQMRPALK GAILSLLGYY 150
    KWEKFVYLYD TERGFSILQA IMEAAVQNNW QVTARSVGNI KDIQEFRRII 200
    EEMDRRQEKR YLIDCEVERI NTILEQVVIL GKHSRGYHYM LANLGFTDIV 250
    LERVMHGGAN ITGFQIVNNE NPMVQQFIQR WVRLDEREFP EAKNAPLKYT 300
    SALTHDAILV IAEAFRYLRR QRVDVSRRGS AGDCLANPAV PWSQGIDIER 350
    ALKMVQVQGM TGNIQFDTYG RRTNYTIDVY EMKVSGSRKA GYWNEYERFV 400
    PFSDQQISND SSSSENRTIV VTTILESPYV MYKKNHEQLE GNERYEGYCV 450
    DLAYEIAKHV RIKYKLSIVG DGKYGARDPE TKIWNGMVGE LVYGRADIAV 500
    APLTITLVRE EVIDFSKPFM SLGISIMIKK PQKSKPGVFS FLDPLAYEIW 550
    MCIVFAYIGV SVVLFLVSRF SPYEWHLEDN NEEPRDPQSP PDPPNEFGIF 600
    NSLWFSLGAF MQQGCDISPR SLSGRIVGGV WWFFTLIIIS SYTANLAAFL 650
    TVERMVSPIE SAEDLAKQTE IAYGTLDSGS TKEFFRRSKI AVYEKMWSYM 700
    KSAEPSVFTK TTADGVARVR KSKGKFAFLL ESTMNEYIEQ RKPCDTMKVG 750
    GNLDSKGYGV ATPKGSALRN AVNLAVLKLN EQGLLDKLKN KWWYDKGECG 800
    SGGGDSKNAC KPCSIETQ 818
    Length:818
    Mass (Da):92,714
    Last modified:May 31, 2011 - v1
    Checksum:i67A7726FFBCC255B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL672232 Genomic DNA. No translation available.
    AL672290 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000139965; ENSMUSP00000116381; ENSMUSG00000001986.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL672232 Genomic DNA. No translation available.
    AL672290 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali F2Z488.
    SMRi F2Z488. Positions 26-815.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi F2Z488.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000139965 ; ENSMUSP00000116381 ; ENSMUSG00000001986 .

    Organism-specific databases

    MGIi MGI:95810. Gria3.

    Phylogenomic databases

    GeneTreei ENSGT00740000115362.

    Miscellaneous databases

    NextBioi 35556293.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi F2Z488.
    Bgeei F2Z488.

    Family and domain databases

    InterProi IPR001828. ANF_lig-bd_rcpt.
    IPR019594. Glu_rcpt_Glu/Gly-bd.
    IPR001320. Iontro_glu_rcpt.
    IPR001508. NMDA_rcpt.
    IPR028082. Peripla_BP_I.
    [Graphical view ]
    Pfami PF01094. ANF_receptor. 1 hit.
    PF00060. Lig_chan. 1 hit.
    PF10613. Lig_chan-Glu_bd. 1 hit.
    [Graphical view ]
    PRINTSi PR00177. NMDARECEPTOR.
    SMARTi SM00918. Lig_chan-Glu_bd. 1 hit.
    SM00079. PBPe. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53822. SSF53822. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiF2Z488_MOUSE
    AccessioniPrimary (citable) accession number: F2Z488
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 31, 2011
    Last sequence update: May 31, 2011
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3