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F2Z488 (F2Z488_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length818 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000116381

Ontologies

Keywords
   Biological processIon transport
Transport
   Cellular componentCell junction
Cell membrane SAAS SAAS001320
Membrane
Postsynaptic cell membrane SAAS SAAS001320
Synapse
   DomainTransmembrane
Transmembrane helix SAAS SAAS001320
   Molecular functionIon channel
Ligand-gated ion channel SAAS SAAS001320
Receptor SAAS SAAS001320
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_procession transmembrane transport

Inferred from Biological aspect of Ancestor. Source: RefGenome

ionotropic glutamate receptor signaling pathway

Inferred from Biological aspect of Ancestor. Source: RefGenome

synaptic transmission, glutamatergic

Inferred from Biological aspect of Ancestor. Source: RefGenome

   Cellular_componentalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex

Inferred from direct assay PubMed 22632720. Source: MGI

cell junction

Inferred from electronic annotation. Source: UniProtKB-KW

dendrite

Inferred from Biological aspect of Ancestor. Source: RefGenome

membrane

Inferred from direct assay PubMed 17093100. Source: MGI

postsynaptic membrane

Inferred from Biological aspect of Ancestor. Source: RefGenome

   Molecular_functionalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

extracellular-glutamate-gated ion channel activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

protein binding

Inferred from physical interaction PubMed 14687553. Source: MGI

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
F2Z488 [UniParc].

Last modified May 31, 2011. Version 1.
Checksum: 67A7726FFBCC255B

FASTA81892,714
        10         20         30         40         50         60 
MGQSVLRAVF FLVLGLLGHS HGGFPNTISI GGLFMRNTVQ EHSAFRFAVQ LYNTNQNTTE 

        70         80         90        100        110        120 
KPFHLNYHVD HLDSSNSFSV TNAFCSQFSR GVYAIFGFYD QMSMNTLTSF CGALHTSFVT 

       130        140        150        160        170        180 
PSFPTDADVQ FVIQMRPALK GAILSLLGYY KWEKFVYLYD TERGFSILQA IMEAAVQNNW 

       190        200        210        220        230        240 
QVTARSVGNI KDIQEFRRII EEMDRRQEKR YLIDCEVERI NTILEQVVIL GKHSRGYHYM 

       250        260        270        280        290        300 
LANLGFTDIV LERVMHGGAN ITGFQIVNNE NPMVQQFIQR WVRLDEREFP EAKNAPLKYT 

       310        320        330        340        350        360 
SALTHDAILV IAEAFRYLRR QRVDVSRRGS AGDCLANPAV PWSQGIDIER ALKMVQVQGM 

       370        380        390        400        410        420 
TGNIQFDTYG RRTNYTIDVY EMKVSGSRKA GYWNEYERFV PFSDQQISND SSSSENRTIV 

       430        440        450        460        470        480 
VTTILESPYV MYKKNHEQLE GNERYEGYCV DLAYEIAKHV RIKYKLSIVG DGKYGARDPE 

       490        500        510        520        530        540 
TKIWNGMVGE LVYGRADIAV APLTITLVRE EVIDFSKPFM SLGISIMIKK PQKSKPGVFS 

       550        560        570        580        590        600 
FLDPLAYEIW MCIVFAYIGV SVVLFLVSRF SPYEWHLEDN NEEPRDPQSP PDPPNEFGIF 

       610        620        630        640        650        660 
NSLWFSLGAF MQQGCDISPR SLSGRIVGGV WWFFTLIIIS SYTANLAAFL TVERMVSPIE 

       670        680        690        700        710        720 
SAEDLAKQTE IAYGTLDSGS TKEFFRRSKI AVYEKMWSYM KSAEPSVFTK TTADGVARVR 

       730        740        750        760        770        780 
KSKGKFAFLL ESTMNEYIEQ RKPCDTMKVG GNLDSKGYGV ATPKGSALRN AVNLAVLKLN 

       790        800        810 
EQGLLDKLKN KWWYDKGECG SGGGDSKNAC KPCSIETQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL672232 Genomic DNA. No translation available.
AL672290 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalF2Z488.
SMRF2Z488. Positions 26-815.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEF2Z488.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000139965; ENSMUSP00000116381; ENSMUSG00000001986.

Organism-specific databases

MGIMGI:95810. Gria3.

Phylogenomic databases

GeneTreeENSGT00740000115362.

Gene expression databases

ArrayExpressF2Z488.
BgeeF2Z488.

Family and domain databases

InterProIPR001828. ANF_lig-bd_rcpt.
IPR019594. Glu_rcpt_Glu/Gly-bd.
IPR001320. Iontro_glu_rcpt.
IPR001508. NMDA_rcpt.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamPF01094. ANF_receptor. 1 hit.
PF00060. Lig_chan. 1 hit.
PF10613. Lig_chan-Glu_bd. 1 hit.
[Graphical view]
PRINTSPR00177. NMDARECEPTOR.
SMARTSM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
[Graphical view]
SUPFAMSSF53822. SSF53822. 1 hit.
ProtoNetSearch...

Other

NextBio35556293.
SOURCESearch...

Entry information

Entry nameF2Z488_MOUSE
AccessionPrimary (citable) accession number: F2Z488
Entry history
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: July 9, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)