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F2Z480 (F2Z480_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length182 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000130971

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processangiogenesis

Inferred from genetic interaction PubMed 16778080. Source: MGI

axonogenesis

Inferred from mutant phenotype PubMed 17951031. Source: MGI

bone development

Inferred from mutant phenotype PubMed 16989802. Source: MGI

bone mineralization

Inferred from mutant phenotype PubMed 12756187. Source: MGI

bone morphogenesis

Inferred from mutant phenotype PubMed 10518547. Source: MGI

branch elongation involved in salivary gland morphogenesis

Inferred from mutant phenotype PubMed 15972105. Source: MGI

branching involved in labyrinthine layer morphogenesis

Inferred from mutant phenotype PubMed 9435295. Source: MGI

branching involved in prostate gland morphogenesis

Inferred from mutant phenotype PubMed 12666202PubMed 17215304. Source: MGI

branching involved in salivary gland morphogenesis

Inferred from mutant phenotype PubMed 11731698. Source: MGI

branching morphogenesis of a nerve

Inferred from mutant phenotype PubMed 17951031. Source: MGI

bud elongation involved in lung branching

Inferred from mutant phenotype PubMed 16989802. Source: MGI

cell fate commitment

Inferred from direct assay PubMed 15509736. Source: MGI

cell-cell signaling

Inferred from mutant phenotype PubMed 15199404. Source: MGI

coronal suture morphogenesis

Inferred from mutant phenotype PubMed 19389359. Source: MGI

digestive tract development

Inferred from mutant phenotype PubMed 15234214. Source: MGI

embryonic cranial skeleton morphogenesis

Inferred from electronic annotation. Source: Ensembl

embryonic digestive tract morphogenesis

Inferred from mutant phenotype PubMed 16618415PubMed 21550054. Source: MGI

embryonic organ development

Inferred from mutant phenotype PubMed 9435295. Source: MGI

embryonic organ morphogenesis

Inferred from mutant phenotype PubMed 15843416. Source: MGI

embryonic pattern specification

Inferred from mutant phenotype PubMed 16618415. Source: MGI

endodermal digestive tract morphogenesis

Inferred from mutant phenotype PubMed 21550054. Source: MGI

epidermis morphogenesis

Inferred from mutant phenotype PubMed 14530295. Source: MGI

epithelial cell differentiation

Inferred from mutant phenotype PubMed 16618415. Source: MGI

epithelial cell proliferation

Inferred from mutant phenotype PubMed 11312155PubMed 15843416. Source: MGI

epithelial cell proliferation involved in salivary gland morphogenesis

Inferred from mutant phenotype PubMed 15972105. Source: MGI

epithelial to mesenchymal transition

Inferred from electronic annotation. Source: Ensembl

epithelial tube branching involved in lung morphogenesis

Inferred from mutant phenotype PubMed 24058167. Source: MGI

fibroblast growth factor receptor signaling pathway

Inferred from mutant phenotype PubMed 9435295. Source: MGI

fibroblast growth factor receptor signaling pathway involved in mammary gland specification

Inferred from mutant phenotype PubMed 16720875. Source: MGI

gland morphogenesis

Inferred from mutant phenotype PubMed 17202188. Source: MGI

hair follicle morphogenesis

Inferred from mutant phenotype PubMed 14530295. Source: MGI

in utero embryonic development

Inferred from mutant phenotype PubMed 9435295. Source: MGI

inner ear morphogenesis

Inferred from mutant phenotype PubMed 10934262. Source: MGI

lacrimal gland development

Inferred from mutant phenotype PubMed 10821755. Source: MGI

lateral sprouting from an epithelium

Inferred from mutant phenotype PubMed 12666202. Source: MGI

lens fiber cell development

Inferred from mutant phenotype PubMed 23136392. Source: MGI

limb bud formation

Inferred from mutant phenotype PubMed 10518547PubMed 9435295. Source: MGI

lung alveolus development

Inferred from mutant phenotype PubMed 16989802. Source: MGI

lung development

Inferred from mutant phenotype PubMed 10518547. Source: MGI

lung lobe morphogenesis

Inferred from mutant phenotype PubMed 16989802. Source: MGI

lung-associated mesenchyme development

Inferred from mutant phenotype PubMed 16989802. Source: MGI

mammary gland bud formation

Inferred from mutant phenotype PubMed 11782400. Source: MGI

membranous septum morphogenesis

Inferred from mutant phenotype PubMed 16687131. Source: MGI

mesenchymal cell differentiation

Inferred from genetic interaction PubMed 16442091. Source: MGI

mesenchymal cell differentiation involved in lung development

Inferred from genetic interaction PubMed 16989802. Source: MGI

mesenchymal cell proliferation involved in lung development

Inferred from mutant phenotype PubMed 16989802. Source: MGI

mesodermal cell differentiation

Inferred from electronic annotation. Source: Ensembl

midbrain development

Inferred from genetic interaction PubMed 17687036. Source: MGI

morphogenesis of embryonic epithelium

Inferred from mutant phenotype PubMed 15843416. Source: MGI

multicellular organism growth

Inferred from mutant phenotype PubMed 16989802. Source: MGI

negative regulation of cell proliferation

Inferred from genetic interaction PubMed 18455718. Source: MGI

negative regulation of epithelial cell proliferation

Inferred from electronic annotation. Source: Ensembl

negative regulation of mitosis

Inferred from genetic interaction PubMed 18455718. Source: MGI

negative regulation of transcription from RNA polymerase II promoter

Inferred from mutant phenotype PubMed 16989802. Source: MGI

neuromuscular junction development

Inferred from mutant phenotype PubMed 17418794. Source: MGI

odontogenesis

Inferred from mutant phenotype PubMed 17951031. Source: MGI

organ growth

Inferred from mutant phenotype PubMed 16618415. Source: MGI

organ morphogenesis

Inferred from mutant phenotype PubMed 12666202. Source: MGI

otic vesicle formation

Inferred from mutant phenotype PubMed 9435295. Source: MGI

outflow tract septum morphogenesis

Inferred from mutant phenotype PubMed 16687131. Source: MGI

positive regulation of ERK1 and ERK2 cascade

Inferred from genetic interaction PubMed 17202188. Source: MGI

positive regulation of Wnt signaling pathway

Inferred from mutant phenotype PubMed 16989802. Source: MGI

positive regulation of canonical Wnt signaling pathway

Inferred from mutant phenotype PubMed 16720875. Source: MGI

positive regulation of cardiac muscle cell proliferation

Inferred from genetic interaction PubMed 15621532. Source: MGI

positive regulation of cell division

Inferred from mutant phenotype PubMed 14530295. Source: MGI

positive regulation of cell proliferation

Inferred from mutant phenotype PubMed 14530295PubMed 15199404. Source: MGI

positive regulation of epithelial cell proliferation

Inferred from genetic interaction PubMed 15972105. Source: MGI

positive regulation of epithelial cell proliferation involved in lung morphogenesis

Inferred from mutant phenotype PubMed 16989802. Source: MGI

positive regulation of mesenchymal cell proliferation

Inferred from genetic interaction PubMed 16540513. Source: MGI

positive regulation of phospholipase activity

Inferred from electronic annotation. Source: Ensembl

positive regulation of smooth muscle cell proliferation

Inferred from electronic annotation. Source: Ensembl

positive regulation of transcription from RNA polymerase II promoter

Inferred from mutant phenotype PubMed 16989802. Source: MGI

post-embryonic development

Inferred from mutant phenotype PubMed 16989802. Source: MGI

prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis

Inferred from mutant phenotype PubMed 17215304. Source: MGI

prostate epithelial cord elongation

Inferred from mutant phenotype PubMed 17215304. Source: MGI

prostate gland morphogenesis

Inferred from mutant phenotype PubMed 18184727. Source: MGI

protein autophosphorylation

Inferred from electronic annotation. Source: Ensembl

regulation of ERK1 and ERK2 cascade

Inferred from mutant phenotype PubMed 16989802. Source: MGI

regulation of branching involved in prostate gland morphogenesis

Inferred from mutant phenotype PubMed 17202188. Source: MGI

regulation of cell fate commitment

Inferred from mutant phenotype PubMed 16989802. Source: MGI

regulation of cell proliferation

Inferred from mutant phenotype PubMed 12756187. Source: MGI

regulation of epithelial cell proliferation

Inferred from mutant phenotype PubMed 17215304PubMed 18184727. Source: MGI

regulation of fibroblast growth factor receptor signaling pathway

Inferred from mutant phenotype PubMed 16989802. Source: MGI

regulation of morphogenesis of a branching structure

Inferred from mutant phenotype PubMed 17202188. Source: MGI

regulation of multicellular organism growth

Inferred from mutant phenotype PubMed 9435295. Source: MGI

regulation of smooth muscle cell differentiation

Inferred from mutant phenotype PubMed 16989802. Source: MGI

regulation of smoothened signaling pathway

Inferred from mutant phenotype PubMed 16618415. Source: MGI

reproductive structure development

Inferred from mutant phenotype PubMed 12666202. Source: MGI

squamous basal epithelial stem cell differentiation involved in prostate gland acinus development

Inferred from mutant phenotype PubMed 17215304. Source: MGI

synaptic vesicle transport

Inferred from mutant phenotype PubMed 17418794. Source: MGI

ureteric bud development

Inferred from genetic interaction PubMed 16442091. Source: MGI

ventricular cardiac muscle tissue morphogenesis

Inferred from mutant phenotype PubMed 16687131. Source: MGI

   Cellular_componentcell cortex

Inferred from electronic annotation. Source: Ensembl

cell surface

Inferred from electronic annotation. Source: Ensembl

extracellular matrix

Inferred from electronic annotation. Source: Ensembl

extracellular region

Traceable author statement PubMed 12024206. Source: MGI

integral component of plasma membrane

Inferred from electronic annotation. Source: Ensembl

nucleus

Inferred from direct assay PubMed 15229180PubMed 15944199. Source: MGI

   Molecular_functionATP binding

Inferred from electronic annotation. Source: InterPro

fibroblast growth factor binding

Inferred from direct assay PubMed 9435295. Source: MGI

fibroblast growth factor-activated receptor activity

Inferred from electronic annotation. Source: Ensembl

protein binding

Inferred from physical interaction PubMed 16436388PubMed 8393815. Source: MGI

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
F2Z480 [UniParc].

Last modified May 31, 2011. Version 1.
Checksum: 580F0677330916DC

FASTA18221,012
        10         20         30         40         50         60 
MKIADFGLAR DINNIDYYKK TTNGRLPVKW MAPEALFDRV YTHQSDVWSF GVLMWEIFTL 

        70         80         90        100        110        120 
GGSPYPGIPV EELFKLLKEG HRMDKPTNCT NELYMMMRDC WHAVPSQRPT FKQLVEDLDR 

       130        140        150        160        170        180 
ILTLTTNEEY LDLTQPLEQY SPSYPDTRSS CSSGDDSVFS PDPMPYEPCL PQYPHINGSV 


KT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC087063 Genomic DNA. No translation available.
AC099609 Genomic DNA. No translation available.
AC099627 Genomic DNA. No translation available.
AC100735 Genomic DNA. No translation available.
AC101690 Genomic DNA. No translation available.
AC101762 Genomic DNA. No translation available.
AC105062 Genomic DNA. No translation available.
AC110885 Genomic DNA. No translation available.
AC111058 Genomic DNA. No translation available.
AC115697 Genomic DNA. No translation available.
AC119806 Genomic DNA. No translation available.
AC122258 Genomic DNA. No translation available.
AC126688 Genomic DNA. No translation available.
AC138624 Genomic DNA. No translation available.
AC145294 Genomic DNA. No translation available.
AC149596 Genomic DNA. No translation available.
AC156606 Genomic DNA. No translation available.
AC157606 Genomic DNA. No translation available.
AC158113 Genomic DNA. No translation available.
AC158314 Genomic DNA. No translation available.
AC159994 Genomic DNA. No translation available.
AC175034 Genomic DNA. No translation available.
AC238818 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalF2Z480.
SMRF2Z480. Positions 1-133.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEF2Z480.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000124096; ENSMUSP00000130971; ENSMUSG00000030849.

Organism-specific databases

MGIMGI:95523. Fgfr2.

Phylogenomic databases

GeneTreeENSGT00670000097694.

Gene expression databases

ArrayExpressF2Z480.
BgeeF2Z480.

Family and domain databases

InterProIPR028175. FGF_rcpt_2.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PANTHERPTHR24416:SF130. PTHR24416:SF130. 1 hit.
PfamPF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
PRINTSPR00109. TYRKINASE.
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSFGFR2. mouse.
NextBio35556288.
SOURCESearch...

Entry information

Entry nameF2Z480_MOUSE
AccessionPrimary (citable) accession number: F2Z480
Entry history
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: July 9, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)