F2Z400 (F2Z400_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
3-phosphoinositide-dependent protein kinase 1 Ensembl ENSMUSP00000111066

Gene names

Name:

Pdpk1 Ensembl ENSMUSP00000111066 MGI 1338068

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000111066

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	457 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000111066

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	hyperosmotic response Inferred from direct assay PubMed 12783890. Source: MGI signal transduction Traceable author statement PubMed 10075713. Source: MGI
Cellular_component	cytoplasmic membrane-bounded vesicle Inferred from direct assay PubMed 12783890. Source: MGI
Molecular_function	3-phosphoinositide-dependent protein kinase activity Inferred from direct assay PubMed 10075713. Source: MGI ATP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F2Z400 [UniParc]. Last modified May 31, 2011. Version 1. Checksum: E72F7240CED5C5A3	FASTA	457	51,471
	10 20 30 40 50 60 MARTTSQLYD AVPIQSSVVL CSCPSPSMVR SQTEPGSSPG IPSGVSRQGS TMDGTTAEAR 70 80 90 100 110 120 PSTNPLQQHP AQLPPQPRKK RPEDFKFGKI LGEGSFSTVV LARELATSRE YAIKILEKRH 130 140 150 160 170 180 IIKENKVPYV TRERDVMSRL DHPFFVKLYF TFQDDEKLYF GLSYAKNGEL LKYIRKIGSF 190 200 210 220 230 240 DETCTRFYTA EIVSALEYLH GKGIIHRDLK PENILLNEDM HIQITDFGTA KVLSPESKQA 250 260 270 280 290 300 RANSFVGTAQ YVSPELLTEK SACKSSDLWA LGCIIYQLVA GLPPFRAGNE YLIFQKIIKL 310 320 330 340 350 360 EYHFPEKFFP KARDLVEKLL VLDATKRLGC EEMEGYGPLK AHPFFETITW ENLHQQTPPK 370 380 390 400 410 420 LTAYLPAMSE DDEDCYGNYD NLLSQFGFMQ VSSSSSSHSL STVETSLPQR SGSNIEQYIH 430 440 450 DLDTNSFELD LQFSEDEKRL LLEKQAGGNP CLTGRTT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000111066.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000111066.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT010502 Genomic DNA. No translation available.
IPI	IPI00831240.
3D structure databases
ProteinModelPortal	F2Z400.
SMR	F2Z400. Positions 45-450.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000115407; ENSMUSP00000111066; ENSMUSG00000024122.
Organism-specific databases
MGI	MGI:1338068. Pdpk1.
Phylogenomic databases
GeneTree	ENSGT00550000074819.
Gene expression databases
ArrayExpress	F2Z400.
Bgee	F2Z400.
Family and domain databases
Gene3D	2.30.29.30. 2 hits.
InterPro	IPR011009. Kinase-like_dom. IPR011993. PH_like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	PDPK1. mouse.
NextBio	35556225.
SOURCE	Search...

Entry information

Entry name

F2Z400_MOUSE

Accession

Primary (citable) accession number: F2Z400

Entry history

Integrated into UniProtKB/TrEMBL:	May 31, 2011
Last sequence update:	May 31, 2011
Last modified:	May 1, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)