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F2Z3Z9

- F2Z3Z9_MOUSE

UniProt

F2Z3Z9 - F2Z3Z9_MOUSE

Protein
Submitted name:

3-phosphoinositide-dependent protein kinase 1

Gene

Pdpk1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (31 May 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 3-phosphoinositide-dependent protein kinase activity Source: MGI
    2. ATP binding Source: InterPro

    GO - Biological processi

    1. hyperosmotic response Source: MGI
    2. signal transduction Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    3-phosphoinositide-dependent protein kinase 1Imported
    Gene namesi
    Name:Pdpk1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 17

    Organism-specific databases

    MGIiMGI:1338068. Pdpk1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. cytoplasmic membrane-bounded vesicle Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiF2Z3Z9.
    BgeeiF2Z3Z9.

    Structurei

    3D structure databases

    ProteinModelPortaliF2Z3Z9.
    SMRiF2Z3Z9. Positions 75-425.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00550000074819.

    Family and domain databases

    Gene3Di2.30.29.30. 1 hit.
    InterProiIPR011009. Kinase-like_dom.
    IPR011993. PH_like_dom.
    IPR000719. Prot_kinase_dom.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F2Z3Z9-1 [UniParc]FASTAAdd to Basket

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    MARTTSQLYD AVPIQSSVVL CSCPSPSMVR SQTEPGSSPG IPSGVSRQGS    50
    TMDGTTAEAR PSTNPLQQHP AQLPPQPRKK RPEDFKFGKI LGEGSFSTVV 100
    LARELATSRE YATRANSFVG TAQYVSPELL TEKSACKSSD LWALGCIIYQ 150
    LVAGLPPFRA GNEYLIFQKI IKLEYHFPEK FFPKARDLVE KLLVLDATKR 200
    LGCEEMEGYG PLKAHPFFET ITWENLHQQT PPKLTAYLPA MSEDDEDCYG 250
    NYDNLLSQFG FMQVSSSSSS HSLSTVETSL PQRSGSNIEQ YIHDLDTNSF 300
    ELDLQFSEDE KRLLLEKQAG GNPWHQFVEN NLILKMGPVD KRKGLFARRR 350
    QLLLTEGPHL YYVDPVNKVL KGEIPWSQEL RPEAKNFKTF FVHTPNRTYY 400
    LMDPSGNAHK WCRKIQEVWR QQYQSNPDAA VQ 432
    Length:432
    Mass (Da):48,807
    Last modified:May 31, 2011 - v1
    Checksum:i813502969FC52E88
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT010502 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000115409; ENSMUSP00000111068; ENSMUSG00000024122.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT010502 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali F2Z3Z9.
    SMRi F2Z3Z9. Positions 75-425.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000115409 ; ENSMUSP00000111068 ; ENSMUSG00000024122 .

    Organism-specific databases

    MGIi MGI:1338068. Pdpk1.

    Phylogenomic databases

    GeneTreei ENSGT00550000074819.

    Miscellaneous databases

    ChiTaRSi PDPK1. mouse.
    NextBioi 35556224.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi F2Z3Z9.
    Bgeei F2Z3Z9.

    Family and domain databases

    Gene3Di 2.30.29.30. 1 hit.
    InterProi IPR011009. Kinase-like_dom.
    IPR011993. PH_like_dom.
    IPR000719. Prot_kinase_dom.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    4. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    5. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiF2Z3Z9_MOUSE
    AccessioniPrimary (citable) accession number: F2Z3Z9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 31, 2011
    Last sequence update: May 31, 2011
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3