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F2Z3X9

- F2Z3X9_MOUSE

UniProt

F2Z3X9 - F2Z3X9_MOUSE

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Protein
Submitted name:

3-phosphoinositide-dependent protein kinase 1

Gene

Pdpk1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. 3-phosphoinositide-dependent protein kinase activity Source: MGI
  2. phospholipase activator activity Source: Ensembl

GO - Biological processi

  1. activation of protein kinase B activity Source: Ensembl
  2. calcium-mediated signaling Source: Ensembl
  3. cell migration Source: Ensembl
  4. cellular response to epidermal growth factor stimulus Source: Ensembl
  5. cellular response to insulin stimulus Source: Ensembl
  6. epidermal growth factor receptor signaling pathway Source: Ensembl
  7. extrinsic apoptotic signaling pathway Source: Ensembl
  8. focal adhesion assembly Source: Ensembl
  9. hyperosmotic response Source: MGI
  10. negative regulation of protein kinase activity Source: Ensembl
  11. negative regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
  12. peptidyl-threonine phosphorylation Source: Ensembl
  13. positive regulation of establishment of protein localization to plasma membrane Source: Ensembl
  14. positive regulation of phospholipase activity Source: Ensembl
  15. positive regulation of release of sequestered calcium ion into cytosol Source: Ensembl
  16. regulation of I-kappaB kinase/NF-kappaB signaling Source: Ensembl
  17. signal transduction Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
3-phosphoinositide-dependent protein kinase 1Imported
Gene namesi
Name:Pdpk1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 17

Organism-specific databases

MGIiMGI:1338068. Pdpk1.

Subcellular locationi

GO - Cellular componenti

  1. cell projection Source: Ensembl
  2. cytoplasm Source: MGI
  3. cytoplasmic membrane-bounded vesicle Source: MGI
  4. cytosol Source: Ensembl
  5. plasma membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiF2Z3X9.
ExpressionAtlasiF2Z3X9. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00550000074819.

Sequencei

Sequence statusi: Fragment.

F2Z3X9-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MVRSQTEPGS SPGIPSGVSR QGSTMDGTTA EARPSTNPLQ QHPAQLPPQP

RKKRPE
Length:56
Mass (Da):5,963
Last modified:May 31, 2011 - v1
Checksum:i902166D678112F87
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei56 – 561Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT010502 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000128997; ENSMUSP00000120548; ENSMUSG00000024122.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT010502 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000128997 ; ENSMUSP00000120548 ; ENSMUSG00000024122 .

Organism-specific databases

MGIi MGI:1338068. Pdpk1.

Phylogenomic databases

GeneTreei ENSGT00550000074819.

Miscellaneous databases

ChiTaRSi PDPK1. mouse.
NextBioi 35556208.
SOURCEi Search...

Gene expression databases

Bgeei F2Z3X9.
ExpressionAtlasi F2Z3X9. baseline and differential.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiF2Z3X9_MOUSE
AccessioniPrimary (citable) accession number: F2Z3X9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: October 29, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3