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F2Z3X6 (F2Z3X6_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length532 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000061942

Ontologies

Keywords
   LigandATP-binding RuleBase RU000304
Nucleotide-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processactivation of protein kinase B activity

Inferred from electronic annotation. Source: Ensembl

cellular response to insulin stimulus

Inferred from electronic annotation. Source: Ensembl

extrinsic apoptotic signaling pathway

Inferred from electronic annotation. Source: Ensembl

focal adhesion assembly

Inferred from electronic annotation. Source: Ensembl

hyperosmotic response

Inferred from direct assay PubMed 12783890. Source: MGI

intracellular signal transduction

Inferred from electronic annotation. Source: Ensembl

negative regulation of protein kinase activity

Inferred from electronic annotation. Source: Ensembl

negative regulation of transforming growth factor beta receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

peptidyl-threonine phosphorylation

Inferred from electronic annotation. Source: Ensembl

positive regulation of establishment of protein localization to plasma membrane

Inferred from electronic annotation. Source: Ensembl

regulation of I-kappaB kinase/NF-kappaB signaling

Inferred from electronic annotation. Source: Ensembl

signal transduction

Traceable author statement PubMed 10075713. Source: MGI

   Cellular_componentcytoplasm

Inferred from direct assay PubMed 12783890. Source: MGI

cytoplasmic membrane-bounded vesicle

Inferred from direct assay PubMed 12783890. Source: MGI

cytosol

Inferred from electronic annotation. Source: Ensembl

plasma membrane

Inferred from electronic annotation. Source: Ensembl

   Molecular_function3-phosphoinositide-dependent protein kinase activity

Inferred from direct assay PubMed 10075713. Source: MGI

ATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
F2Z3X6 [UniParc].

Last modified May 31, 2011. Version 1.
Checksum: 10EEAF5D197B157C

FASTA53260,935
        10         20         30         40         50         60 
MVRSQTEPGS SPGIPSGVSR QGSTMDGTTA EARPSTNPLQ QHPAQLPPQP RKKRPEDFKF 

        70         80         90        100        110        120 
GKILGEGSFS TVVLARELAT SREYAIKILE KRHIIKENKV PYVTRERDVM SRLDHPFFVK 

       130        140        150        160        170        180 
LYFTFQDDEK LYFGLSYAKN GELLKYIRKI GSFDETCTRF YTAEIVSALE YLHGKGIIHR 

       190        200        210        220        230        240 
DLKPENILLN EDMHIQITDF GTAKVLSPES KQARANSFVG TAQYVSPELL TEKSACKSSD 

       250        260        270        280        290        300 
LWALGCIIYQ LVAGLPPFRA GNEYLIFQKI IKLEYHFPEK FFPKARDLVE KLLVLDATKR 

       310        320        330        340        350        360 
LGCEEMEGYG PLKAHPFFET ITWENLHQQT PPKLTAYLPA MSEDDEDCYG NYDNLLSQFG 

       370        380        390        400        410        420 
FMQVSSSSSS HSLSTVETSL PQRSGSNIEQ YIHDLDTNSF ELDLQFSEDE KRLLLEKQAG 

       430        440        450        460        470        480 
GNPWHQFVEN NLILKMGPVD KRKGLFARRR QLLLTEGPHL YYVDPVNKVL KGEIPWSQEL 

       490        500        510        520        530 
RPEAKNFKTF FVHTPNRTYY LMDPSGNAHK WCRKIQEVWR QQYQSNPDAA VQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CT010502 Genomic DNA. No translation available.
RefSeqNP_001273591.1. NM_001286662.1.
XP_006523886.1. XM_006523823.1.
XP_006523887.1. XM_006523824.1.
XP_006523888.1. XM_006523825.1.
XP_006523889.1. XM_006523826.1.
XP_006523892.1. XM_006523829.1.
UniGeneMm.10504.

3D structure databases

ProteinModelPortalF2Z3X6.
SMRF2Z3X6. Positions 18-525.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000052462; ENSMUSP00000061942; ENSMUSG00000024122.
GeneID18607.

Organism-specific databases

MGIMGI:1338068. Pdpk1.

Phylogenomic databases

GeneTreeENSGT00550000074819.

Gene expression databases

ArrayExpressF2Z3X6.
BgeeF2Z3X6.

Family and domain databases

Gene3D2.30.29.30. 2 hits.
InterProIPR011009. Kinase-like_dom.
IPR011993. PH_like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSPDPK1. mouse.
NextBio35556205.
SOURCESearch...

Entry information

Entry nameF2Z3X6_MOUSE
AccessionPrimary (citable) accession number: F2Z3X6
Entry history
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: April 16, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)