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Protein
Submitted name:

Parafibromin

Gene

Cdc73

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-201722 Formation of the beta-catenin:TCF transactivating complex
R-RNO-5632684 Hedgehog 'on' state
R-RNO-674695 RNA Polymerase II Pre-transcription Events
R-RNO-75955 RNA Polymerase II Transcription Elongation
R-RNO-8866654 E3 ubiquitin ligases ubiquitinate target proteins

Names & Taxonomyi

Protein namesi
Submitted name:
ParafibrominImported
Gene namesi
Name:Cdc73Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 13

Organism-specific databases

RGDi1311766 Cdc73

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiF2Z3T0

Expressioni

Gene expression databases

BgeeiENSRNOG00000003258

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliF2Z3T0
SMRiF2Z3T0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 297CDC73_NInterPro annotationAdd BLAST297
Domaini357 – 520CDC73_CInterPro annotationAdd BLAST164

Phylogenomic databases

eggNOGiKOG3786 Eukaryota
COG5157 LUCA
GeneTreeiENSGT00390000001114
OMAiKKLQGCQ
OrthoDBiEOG091G0A8X
TreeFamiTF313016

Family and domain databases

Gene3Di3.40.50.11990, 1 hit
InterProiView protein in InterPro
IPR007852 Cdc73/Parafibromin
IPR031336 CDC73_C
IPR038103 CDC73_C_sf
IPR032041 Cdc73_N
PANTHERiPTHR12466 PTHR12466, 1 hit
PfamiView protein in Pfam
PF05179 CDC73_C, 1 hit
PF16050 CDC73_N, 1 hit

Sequencei

Sequence statusi: Complete.

F2Z3T0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADVLSVLRQ YNIQKKEIVV KGDEVIFGEF SWPKNVKTNY VVWGTGKEGQ
60 70 80 90 100
PREYYTLDSI LFLLNNVHLS HPVYVRRAAT ENIPVVRRPD RKDLLGYLNG
110 120 130 140 150
EASTSASIDR SAPLEIGLQR STQVKRAADE VLAEAKKPRI EDEECVRLDK
160 170 180 190 200
ERLAARLEGH KEGIVQTEQI RSLSEAMSVE KIAAIKAKIM AKKRSTIKTD
210 220 230 240 250
LDDDITALKQ RSFVDAEVDV TRDIVSRERV WRTRTTILQS TGKNFSKNIF
260 270 280 290 300
AILQSVKARE EGRAPEQRPA PNAAPVDPTL RTKQPIPAAY NRYDQERFKG
310 320 330 340 350
KEETEGFKID TMGTYHGMTL KSVTEGASAR KTQTPAAQPV PRPVSQARPP
360 370 380 390 400
PNQKKGSRTP IIIIPAATTS LITMLNAKDL LQDLKFVPSD EKKKQGCQRE
410 420 430 440 450
NETLIQRRKD QMQPGGTAIS VTVPYRVVDQ PLKLMPQDWD RVVAVFVQGP
460 470 480 490 500
AWQFKGWPWL LPDGSPVDIF AKIKAFHLKY DEVRLDPNVQ KWDVTVLELS
510 520 530
YHKRHLDRPV FLRFWETLDR YMVKHKSHLR F
Length:531
Mass (Da):60,577
Last modified:May 31, 2011 - v1
Checksum:i894A7448DBC0E793
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07021202 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000004495; ENSRNOP00000004495; ENSRNOG00000003258

Similar proteinsi

Entry informationi

Entry nameiF2Z3T0_RAT
AccessioniPrimary (citable) accession number: F2Z3T0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: May 23, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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