UniProtKB - F2Z381 (F2Z381_HUMAN)
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Protein
Submitted name:
POU class 5 homeobox 1 transcript variant 6
Gene
POU5F1
Organism
Homo sapiens (Human)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 34 – 93 | HomeoboxPROSITE-ProRule annotationAdd BLAST | 60 |
GO - Molecular functioni
- DNA binding transcription factor activity Source: InterPro
- sequence-specific DNA binding Source: InterPro
GO - Biological processi
- transcription, DNA-templated Source: UniProtKB-UniRule
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationSAAS annotationImported |
Biological process | Transcription, Transcription regulationPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: POU class 5 homeobox 1 transcript variant 6ImportedSubmitted name: POU class 5 homeobox 1 transcript variant OCT4B1ImportedSubmitted name: POU class 5 homeobox 1 transcript variant OCT4B2ImportedSubmitted name: POU class 5 homeobox 1 transcript variant OCT4B3ImportedSubmitted name: POU domain, class 5, transcription factor 1Imported |
Gene namesi | Name:POU5F1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000204531.15. |
HGNCi | HGNC:9221. POU5F1. |
Subcellular locationi
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationSAAS annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 16 | POU-specificInterPro annotationAdd BLAST | 16 | |
Domaini | 32 – 92 | HomeoboxInterPro annotationAdd BLAST | 61 |
Keywords - Domaini
HomeoboxPROSITE-ProRule annotationSAAS annotationImportedPhylogenomic databases
eggNOGi | KOG3802. Eukaryota. ENOG410XQ7X. LUCA. |
GeneTreei | ENSGT00760000118935. |
Family and domain databases
CDDi | cd00086. homeodomain. 1 hit. |
InterProi | View protein in InterPro IPR009057. Homeobox-like_sf. IPR017970. Homeobox_CS. IPR001356. Homeobox_dom. IPR013847. POU. IPR000327. POU_dom. IPR015585. POU_dom_5. |
PANTHERi | PTHR11636:SF86. PTHR11636:SF86. 1 hit. |
Pfami | View protein in Pfam PF00046. Homeobox. 1 hit. |
PRINTSi | PR00028. POUDOMAIN. |
SMARTi | View protein in SMART SM00389. HOX. 1 hit. |
SUPFAMi | SSF46689. SSF46689. 1 hit. |
PROSITEi | View protein in PROSITE PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. PS51179. POU_3. 1 hit. |
i Sequence
Sequence statusi: Complete.
F2Z381-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MCKLRPLLQK WVEEADNNEN LQEICKAETL VQARKRKRTS IENRVRGNLE
60 70 80 90 100
NLFLQCPKPT LQQISHIAQQ LGLEKDVVRV WFCNRRQKGK RSSSDYAQRE
110 120 130 140 150
DFEAAGSPFS GGPVSFPLAP GPHFGTPGYG SPHFTALYSS VPFPEGEAFP
160
PVSVTTLGSP MHSN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL662844 Genomic DNA. No translation available. KF880692 mRNA. Translation: AID57228.1. KF880693 mRNA. Translation: AID57229.1. KJ624996 mRNA. Translation: AIK29475.1. KJ700311 mRNA. Translation: AIK29476.1. |
RefSeqi | NP_001272915.1. NM_001285986.1. |
UniGenei | Hs.249184. |
Genome annotation databases
Ensembli | ENST00000441888; ENSP00000389359; ENSG00000204531. ENST00000471529; ENSP00000425083; ENSG00000204531. ENST00000512818; ENSP00000425479; ENSG00000204531. ENST00000513407; ENSP00000475512; ENSG00000204531. |
GeneIDi | 5460. |
UCSCi | uc032wqt.2. human. |
Similar proteinsi
Entry informationi
Entry namei | F2Z381_HUMAN | |
Accessioni | F2Z381Primary (citable) accession number: F2Z381 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 31, 2011 |
Last sequence update: | May 31, 2011 | |
Last modified: | March 28, 2018 | |
This is version 68 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |