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F2Z333

- CA233_HUMAN

UniProt

F2Z333 - CA233_HUMAN

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Protein

Fibronectin type-III domain-containing transmembrane protein C1orf233

Gene

C1orf233

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Fibronectin type-III domain-containing transmembrane protein C1orf233
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:42951. C1orf233.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 226226Fibronectin type-III domain-containing transmembrane protein C1orf233PRO_0000416238Add
BLAST
Signal peptidei1 – 2020Sequence AnalysisAdd
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi86 – 861N-linked (GlcNAc...)Sequence Analysis
Glycosylationi109 – 1091N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiF2Z333.

Expressioni

Gene expression databases

BgeeiF2Z333.

Structurei

3D structure databases

ProteinModelPortaliF2Z333.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini21 – 182162ExtracellularSequence AnalysisAdd
BLAST
Topological domaini204 – 22623CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei183 – 20321HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini74 – 16693Fibronectin type-IIIAdd
BLAST

Sequence similaritiesi

Contains 1 fibronectin type-III domain.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00550000076432.
InParanoidiF2Z333.
OMAiAECVEFT.
OrthoDBiEOG7XDBHD.
PhylomeDBiF2Z333.
TreeFamiTF332961.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

F2Z333-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRAPPLLLLL AACAPPPCAA AAPTPPGWEP TPDAPWCPYK VLPEGPEAGG
60 70 80 90 100
GRLCFRSPAR GFRCQAPGCV LHAPAGRSLR ASVLRNRSVL LQWRLAPAAA
110 120 130 140 150
RRVRAFALNC SWRGAYTRFP CERVLLGASC RDYLLPDVHD SVLYRLCLQP
160 170 180 190 200
LPLRAGPAAA APETPEPAEC VEFTAEPAGM QDIVVAMTAV GGSICVMLVV
210 220
ICLLVAYITE NLMRPALARP GLRRHP
Length:226
Mass (Da):24,218
Last modified:May 31, 2011 - v1
Checksum:iF4A076C9226DA5FE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL691432 Genomic DNA. No translation available.
CCDSiCCDS55559.1.
RefSeqiNP_001229588.1. NM_001242659.1.
UniGeneiHs.528816.

Genome annotation databases

EnsembliENST00000422725; ENSP00000389111; ENSG00000228594.
GeneIDi643988.
KEGGihsa:643988.
UCSCiuc021oes.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL691432 Genomic DNA. No translation available.
CCDSi CCDS55559.1.
RefSeqi NP_001229588.1. NM_001242659.1.
UniGenei Hs.528816.

3D structure databases

ProteinModelPortali F2Z333.
ModBasei Search...
MobiDBi Search...

Proteomic databases

MaxQBi F2Z333.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000422725 ; ENSP00000389111 ; ENSG00000228594 .
GeneIDi 643988.
KEGGi hsa:643988.
UCSCi uc021oes.1. human.

Organism-specific databases

CTDi 643988.
GeneCardsi GC01M001537.
HGNCi HGNC:42951. C1orf233.
neXtProti NX_F2Z333.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00550000076432.
InParanoidi F2Z333.
OMAi AECVEFT.
OrthoDBi EOG7XDBHD.
PhylomeDBi F2Z333.
TreeFami TF332961.

Miscellaneous databases

GenomeRNAii 643988.
NextBioi 115679.

Gene expression databases

Bgeei F2Z333.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiCA233_HUMAN
AccessioniPrimary (citable) accession number: F2Z333
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2012
Last sequence update: May 31, 2011
Last modified: October 29, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3