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Protein

Fibronectin type III domain-containing protein 10

Gene

FNDC10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Fibronectin type III domain-containing protein 10
Gene namesi
Name:FNDC10
Synonyms:C1orf233
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000228594.3
HGNCiHGNC:42951 FNDC10
neXtProtiNX_F2Z333

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini21 – 182ExtracellularSequence analysisAdd BLAST162
Transmembranei183 – 203HelicalSequence analysisAdd BLAST21
Topological domaini204 – 226CytoplasmicSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000228594

Polymorphism and mutation databases

BioMutaiC1orf233

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004162381 – 226Fibronectin type III domain-containing protein 10Add BLAST226
Signal peptidei1 – 20Sequence analysisAdd BLAST20

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi86N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi109N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiF2Z333
PaxDbiF2Z333
PRIDEiF2Z333

Expressioni

Gene expression databases

BgeeiENSG00000228594
GenevisibleiF2Z333 HS

Structurei

3D structure databases

ProteinModelPortaliF2Z333
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini74 – 166Fibronectin type-IIIAdd BLAST93

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410JB9U Eukaryota
ENOG410Z0X2 LUCA
GeneTreeiENSGT00550000076432
InParanoidiF2Z333
OMAiTENLMRP
OrthoDBiEOG091G0HGI
PhylomeDBiF2Z333
TreeFamiTF332961

Family and domain databases

InterProiView protein in InterPro
IPR034446 Fndc10
PANTHERiPTHR39233 PTHR39233, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

F2Z333-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAPPLLLLL AACAPPPCAA AAPTPPGWEP TPDAPWCPYK VLPEGPEAGG
60 70 80 90 100
GRLCFRSPAR GFRCQAPGCV LHAPAGRSLR ASVLRNRSVL LQWRLAPAAA
110 120 130 140 150
RRVRAFALNC SWRGAYTRFP CERVLLGASC RDYLLPDVHD SVLYRLCLQP
160 170 180 190 200
LPLRAGPAAA APETPEPAEC VEFTAEPAGM QDIVVAMTAV GGSICVMLVV
210 220
ICLLVAYITE NLMRPALARP GLRRHP
Length:226
Mass (Da):24,218
Last modified:May 31, 2011 - v1
Checksum:iF4A076C9226DA5FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL691432 Genomic DNA No translation available.
CCDSiCCDS55559.1
RefSeqiNP_001229588.1, NM_001242659.1
UniGeneiHs.528816

Genome annotation databases

EnsembliENST00000422725; ENSP00000389111; ENSG00000228594
GeneIDi643988
KEGGihsa:643988
UCSCiuc021oes.2 human

Similar proteinsi

Entry informationi

Entry nameiFND10_HUMAN
AccessioniPrimary (citable) accession number: F2Z333
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2012
Last sequence update: May 31, 2011
Last modified: February 28, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health