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F2Z333

- CA233_HUMAN

UniProt

F2Z333 - CA233_HUMAN

Protein

Fibronectin type-III domain-containing transmembrane protein C1orf233

Gene

C1orf233

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 19 (01 Oct 2014)
      Sequence version 1 (31 May 2011)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Fibronectin type-III domain-containing transmembrane protein C1orf233
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 1

    Organism-specific databases

    HGNCiHGNC:42951. C1orf233.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 226226Fibronectin type-III domain-containing transmembrane protein C1orf233PRO_0000416238Add
    BLAST
    Signal peptidei1 – 2020Sequence AnalysisAdd
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi86 – 861N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi109 – 1091N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    MaxQBiF2Z333.

    Expressioni

    Gene expression databases

    BgeeiF2Z333.

    Structurei

    3D structure databases

    ProteinModelPortaliF2Z333.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini21 – 182162ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini204 – 22623CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei183 – 20321HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini74 – 16693Fibronectin type-IIIAdd
    BLAST

    Sequence similaritiesi

    Contains 1 fibronectin type-III domain.Curated

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    OMAiAECVEFT.
    OrthoDBiEOG7XDBHD.
    PhylomeDBiF2Z333.
    TreeFamiTF332961.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    F2Z333-1 [UniParc]FASTAAdd to Basket

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    MRAPPLLLLL AACAPPPCAA AAPTPPGWEP TPDAPWCPYK VLPEGPEAGG    50
    GRLCFRSPAR GFRCQAPGCV LHAPAGRSLR ASVLRNRSVL LQWRLAPAAA 100
    RRVRAFALNC SWRGAYTRFP CERVLLGASC RDYLLPDVHD SVLYRLCLQP 150
    LPLRAGPAAA APETPEPAEC VEFTAEPAGM QDIVVAMTAV GGSICVMLVV 200
    ICLLVAYITE NLMRPALARP GLRRHP 226
    Length:226
    Mass (Da):24,218
    Last modified:May 31, 2011 - v1
    Checksum:iF4A076C9226DA5FE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL691432 Genomic DNA. No translation available.
    CCDSiCCDS55559.1.
    RefSeqiNP_001229588.1. NM_001242659.1.
    UniGeneiHs.528816.

    Genome annotation databases

    EnsembliENST00000422725; ENSP00000389111; ENSG00000228594.
    GeneIDi643988.
    KEGGihsa:643988.
    UCSCiuc021oes.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL691432 Genomic DNA. No translation available.
    CCDSi CCDS55559.1.
    RefSeqi NP_001229588.1. NM_001242659.1.
    UniGenei Hs.528816.

    3D structure databases

    ProteinModelPortali F2Z333.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    MaxQBi F2Z333.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000422725 ; ENSP00000389111 ; ENSG00000228594 .
    GeneIDi 643988.
    KEGGi hsa:643988.
    UCSCi uc021oes.1. human.

    Organism-specific databases

    CTDi 643988.
    GeneCardsi GC01M001537.
    HGNCi HGNC:42951. C1orf233.
    neXtProti NX_F2Z333.
    GenAtlasi Search...

    Phylogenomic databases

    OMAi AECVEFT.
    OrthoDBi EOG7XDBHD.
    PhylomeDBi F2Z333.
    TreeFami TF332961.

    Miscellaneous databases

    GenomeRNAii 643988.
    NextBioi 115679.

    Gene expression databases

    Bgeei F2Z333.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
      , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
      Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiCA233_HUMAN
    AccessioniPrimary (citable) accession number: F2Z333
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 21, 2012
    Last sequence update: May 31, 2011
    Last modified: October 1, 2014
    This is version 19 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3