F2X654 (F2X654_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
MHC class II antigen EMBL AEA49853.1

Gene names

Name:

HLA-DRB1 EMBL AEA49853.1

Organism

Homo sapiens (Human) EMBL AEA49853.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	89 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Immunity
Cellular component	MHC II RuleBase RU000321 Membrane
Domain	Transmembrane RuleBase RU000321
Gene Ontology (GO)
Biological_process	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Inferred from electronic annotation. Source: UniProtKB-KW immune response Inferred from electronic annotation. Source: InterPro
Cellular_component	MHC class II protein complex Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AEA49853.1
	Non-terminal residue	89	1	EMBL AEA49853.1

Sequences

	Sequence		Length	Mass (Da)
	F2X654 [UniParc]. Last modified May 31, 2011. Version 1. Checksum: B0DADC7D8884DEA9	FASTA	89	10,834
	10 20 30 40 50 60 RFLWQPKREC HFFNGTERVR FLDRYFYNQE ESVRFDSDVG EFRAVTELGR PDAEYWNSQK 70 80 DILEQARAAV DTYCRHNYGV VESFTVQRR

References

[1]	Cereb N., Yang S.Y. Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	HQ337765 Genomic DNA. Translation: AEA49853.1.
IPI	IPI00472169.
3D structure databases
ProteinModelPortal	F2X654.
ModBase	Search...
Proteomic databases
PRIDE	F2X654.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	F2X654.
Bgee	F2X654.
Family and domain databases
Gene3D	3.10.320.10. 1 hit.
InterPro	IPR011162. MHC_I/II-like_Ag-recog. IPR014745. MHC_II_a/b_N. IPR000353. MHC_II_b_N. [Graphical view]
Pfam	PF00969. MHC_II_beta. 1 hit. [Graphical view]
ProDom	PD000328. MHC_II_b_N. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00921. MHC_II_beta. 1 hit. [Graphical view]
SUPFAM	SSF54452. MHC_I/II-like_Ag-recog. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	HLA-DRB1. human.
NextBio	35505983.

Entry information

Entry name

F2X654_HUMAN

Accession

Primary (citable) accession number: F2X654

Entry history

Integrated into UniProtKB/TrEMBL:	May 31, 2011
Last sequence update:	May 31, 2011
Last modified:	April 3, 2013
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.