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F2RJX4 (F2RJX4_STRVP) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU004247 HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site411Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2741Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1401Substrate By similarity HAMAP-Rule MF_01201
Binding site3221Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue411N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
F2RJX4 [UniParc].

Last modified May 31, 2011. Version 1.
Checksum: 354E8FA1AB2CC23D

FASTA38240,210
        10         20         30         40         50         60 
MTETPPPRRA RAEIDLGALR ANVRTLRARV APHVRIMAVV KADAYGHGAV RCARAALDAG 

        70         80         90        100        110        120 
ADWLGTATPH EALALRAAGI TDVPVMCWLW TPGDPWDQGI EAGLDMSVSG MWALEEVVRA 

       130        140        150        160        170        180 
ARATGGVARV QLKADTGLGR NGCQPADWPE LVGEALKAEA EGLVEVTGLW SHFACADEPH 

       190        200        210        220        230        240 
HPSIAAQLDV FRSMLDYAEK AGVRPEVRHI ANSPATLTLP EAHFDLVRPG IAMYGVSPSP 

       250        260        270        280        290        300 
ELGTSAELGL RPVMSLKASV ALVKRVPAGH GVSYGHHYVT DAETTLGLVP LGYADGVPRH 

       310        320        330        340        350        360 
ASGRGPVLVD GTVRTVAGRV AMDQFVVDLG GDVPAPGTEA VLFGPGDLGE PTAEDWAVAA 

       370        380 
DTIAYEIVTR IGARVPRVYL GE 

« Hide

References

[1]"Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes."
Pullan S.T., Chandra G., Bibb M.J., Merrick M.
BMC Genomics 12:175-175(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FR845719 Genomic DNA. Translation: CCA57708.1.
RefSeqYP_006879967.1. NC_018750.1.

3D structure databases

ProteinModelPortalF2RJX4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCA57708; CCA57708; SVEN_4422.
GeneID13819580.
KEGGsve:SVEN_4422.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF2RJX4_STRVP
AccessionPrimary (citable) accession number: F2RJX4
Entry history
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: February 19, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)