ID   F2R8H7_STRVP            Unreviewed;       309 AA.
AC   F2R8H7;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=ATP-dependent DNA ligase {ECO:0000313|EMBL:CCA53895.1};
DE            EC=6.5.1.1 {ECO:0000313|EMBL:CCA53895.1};
GN   OrderedLocusNames=SVEN_0608 {ECO:0000313|EMBL:CCA53895.1};
OS   Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM
OS   4526 / NBRC 13096 / PD 04745).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=953739 {ECO:0000313|EMBL:CCA53895.1, ECO:0000313|Proteomes:UP000006854};
RN   [1] {ECO:0000313|EMBL:CCA53895.1, ECO:0000313|Proteomes:UP000006854}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10712 {ECO:0000313|EMBL:CCA53895.1};
RX   PubMed=21463507; DOI=10.1186/1471-2164-12-175;
RA   Pullan S.T., Bibb M.J., Merrick M.;
RT   "Genome-wide analysis of the role of GlnR in Streptomyces venezuelae
RT   provides new insights into global nitrogen regulation in actinomycetes.";
RL   BMC Genomics 12:175-175(2011).
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DR   EMBL; FR845719; CCA53895.1; -; Genomic_DNA.
DR   RefSeq; WP_015031814.1; NZ_JABVZO010000096.1.
DR   AlphaFoldDB; F2R8H7; -.
DR   STRING; 953739.SVEN_0608; -.
DR   GeneID; 69862809; -.
DR   KEGG; sve:SVEN_0608; -.
DR   PATRIC; fig|953739.5.peg.792; -.
DR   eggNOG; COG3285; Bacteria.
DR   HOGENOM; CLU_008325_1_1_11; -.
DR   OrthoDB; 4296267at2; -.
DR   Proteomes; UP000006854; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   CDD; cd04861; LigD_Pol_like; 1.
DR   Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR   InterPro; IPR014145; LigD_pol_dom.
DR   NCBIfam; TIGR02778; ligD_pol; 1.
DR   PANTHER; PTHR42705; BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD; 1.
DR   PANTHER; PTHR42705:SF2; MULTIFUNCTIONAL NON-HOMOLOGOUS END JOINING DNA REPAIR PROTEIN LIGD; 1.
DR   Pfam; PF21686; LigD_Prim-Pol; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:CCA53895.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006854}.
FT   DOMAIN          36..286
FT                   /note="DNA ligase D polymerase"
FT                   /evidence="ECO:0000259|Pfam:PF21686"
SQ   SEQUENCE   309 AA;  34610 MW;  F9411103C1BFAC89 CRC64;
     MTPTSRTAPP ERVRAGRRTV EIRRPDKVLF PGDGLTKADL AGYYRTVAHR MLPHLRGRPL
     MLERHPDGID GPAFMQKDVP DHFPDWVHRA ELPKEGGTVT YVLCEDTATL LYLAGQACTT
     PHRFLSRADR PDRPDRLVFD LDPADEDFAP VREAALGLHR LLDELELPSS LMTTGSRGLH
     VVVALDRRAP FDDVRAFARG VADVLASRHP DRFTTEARKN ARRGRLYLDV QRNGYAQTAV
     VPYAVRARPG APVAAPLAWS DLDDPDLTAR RWTVATVDGL LKDDPWHDPP RPRSLRRARD
     LLAELTRGG
//