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F2R5D4 (F2R5D4_STRVP) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length379 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain159 – 369211ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding195 – 25056ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3231Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3361Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3361Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3381Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
F2R5D4 [UniParc].

Last modified May 31, 2011. Version 1.
Checksum: 7173473E226A0CD8

FASTA37940,860
        10         20         30         40         50         60 
MSENTQSPRK PRVAVVFGGR SSEHAISVVT AGAVLSAIDR DKYDVLPIGI TTDGRWALTA 

        70         80         90        100        110        120 
DAPERMAIAD RALPNVADLA ESETGGVVLS VDPADRQVVL TEPGAVPKAL GEVDVVFPML 

       130        140        150        160        170        180 
HGPYGEDGTL QGLLELSGVP YVGAGVLASA VGQDKEYMKR VFVSFGLPVG PYEVIRPREW 

       190        200        210        220        230        240 
EQNPAAARKK IVEFAAEHGW PLFVKPARGG SSMGITKVDD LSGLDEAIEE ARRHDPKILV 

       250        260        270        280        290        300 
ESLLRGREIE CGVLEFEDGP RASVPAEIPP VTNHDFYDFE AKYIDSASGI VPAPIGDEAT 

       310        320        330        340        350        360 
AEIQRLAVAA YEAVSCEGLV RADFFLTEDG DFVINEINTM PGFTPISMYP RMWQESGVSY 

       370 
PELVDRLIQA ALTRSTGLR 

« Hide

References

[1]"Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes."
Pullan S.T., Chandra G., Bibb M.J., Merrick M.
BMC Genomics 12:175-175(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FR845719 Genomic DNA. Translation: CCA58538.1.
RefSeqYP_006880797.1. NC_018750.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCA58538; CCA58538; SVEN_5252.
GeneID13824707.
KEGGsve:SVEN_5252.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF2R5D4_STRVP
AccessionPrimary (citable) accession number: F2R5D4
Entry history
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: February 19, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)