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F2QC38 (F2QC38_STROU) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase RuleBase RU004247 HAMAP-Rule MF_01201

EC=5.1.1.1 RuleBase RU004247 HAMAP-Rule MF_01201
Gene names
Ordered Locus Names:SOR_0544 EMBL CBZ00206.1
OrganismStreptococcus oralis (strain Uo5) [Complete proteome] [HAMAP]
Taxonomic identifier927666 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU004247 HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site401Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2631Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1361Substrate By similarity HAMAP-Rule MF_01201
Binding site3101Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue401N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
F2QC38 [UniParc].

Last modified May 31, 2011. Version 1.
Checksum: 81A01B4714F5D050

FASTA36739,850
        10         20         30         40         50         60 
MKASPHRPTK ALICLEAIQQ NIHQMGVHIP EGTLKWAVVK ANAYGHGAVA VAKAIQDDVD 

        70         80         90        100        110        120 
GFCVSNIDEA IELRQARLSK RILILGVSEI EAIGLAKEYD ITLTVAGLEW VRALVATGAD 

       130        140        150        160        170        180 
LSGLSVHLKI DSGMGRIGFR EASEAEQAQD LLKQHGARVE GIFTHFATAD EESDTYFNNQ 

       190        200        210        220        230        240 
LERFKAILAS MKEVPELVHA SNSATTLWHA ETIFNAVRMG DAMYGLNPSG EVLDLPYDLT 

       250        260        270        280        290        300 
PALTLESALV HVKTVLAGAC MGYGATYQAD SEQIIATVPI GYADGWTRDM QNFSVLVDGQ 

       310        320        330        340        350        360 
ACPIVGRVSM DQITIRLPKV YPLGTKVTLI GTNGDKEITA TQVAAYRGTI NYEVVCLLSD 


RIPREYH 

« Hide

References

[1]"Genome of Streptococcus oralis strain Uo5."
Reichmann P., Nuhn M., Denapaite D., Bruckner R., Henrich B., Maurer P., Rieger M., Klages S., Reinhard R., Hakenbeck R.
J. Bacteriol. 193:2888-2889(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Uo5.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FR720602 Genomic DNA. Translation: CBZ00206.1.
RefSeqYP_004325547.1. NC_015291.1.

3D structure databases

ProteinModelPortalF2QC38.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBZ00206; CBZ00206; SOR_0544.
GeneID10415706.
KEGGsor:SOR_0544.
PATRIC54423671. VBIStrOra177080_0469.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycSORA927666:GH8G-544-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF2QC38_STROU
AccessionPrimary (citable) accession number: F2QC38
Entry history
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: February 19, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)