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F2NV13 (RNC_TRES6) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease 3

EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
Name:rnc
Ordered Locus Names:Tresu_0151
OrganismTreponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091) [Complete proteome] [HAMAP]
Taxonomic identifier869209 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 369369Ribonuclease 3 HAMAP-Rule MF_00104
PRO_0000416614

Regions

Domain6 – 142137RNase III
Domain272 – 34170DRBM

Sites

Active site501 Potential
Active site1311 By similarity
Metal binding461Magnesium By similarity
Metal binding1281Magnesium By similarity
Metal binding1311Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
F2NV13 [UniParc].

Last modified May 31, 2011. Version 1.
Checksum: 6657D14A15ED1B13

FASTA36942,826
        10         20         30         40         50         60 
MNRQDIGFVQ SSINYQFKNL QLLEQAFTRK SYSEEHPELQ NNEVLEFYGD EILDFFVTKM 

        70         80         90        100        110        120 
MYKRFSRILN NELVSEKNEG ELTKLKSILV SKESLARCMY NIGFSKFLYL GKSDEKNEVY 

       130        140        150        160        170        180 
KSKSVNEDLF EAIIGAVAAD CDWNYEKLEK VCRTMLDMET TNGYLALLVK EKSHRLGFGE 

       190        200        210        220        230        240 
PCYRPFAWQT DNPEDWQSDN LFNMGIGFGG FGSTSKNPKT GKHEYGIQVG ENKFTGIGDG 

       250        260        270        280        290        300 
IAQAKLNAEQ KAYHFLIQEE IKQQFQNLDY TNPASTLHEL FQKKVIMEVR YEFNEYHDEN 

       310        320        330        340        350        360 
GNPIWNCKAI LEGYGTFEAD NASKKQVKQD ASLKLLKFIA KTKIEQTEKW EIPTFYHGMA 


RIWHDEGKI 

« Hide

References

[1]"The complete genome of chromosome of Treponema succinifaciens DSM 2489."
Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L., Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Teshima H., Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V. expand/collapse author list , Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P., Eisen J.A.
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33096 / DSM 2489 / 6091.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002631 Genomic DNA. Translation: AEB13117.1.
RefSeqYP_004364414.1. NC_015385.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEB13117; AEB13117; Tresu_0151.
GeneID10430238.
KEGGtsu:Tresu_0151.
PATRIC54426797. VBITreSuc166698_0157.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK03685.

Enzyme and pathway databases

BioCycTSUC869209:GHSS-155-MONOMER.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF14622. Ribonucleas_3_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. SSF69065. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_TRES6
AccessionPrimary (citable) accession number: F2NV13
Entry history
Integrated into UniProtKB/Swiss-Prot: April 18, 2012
Last sequence update: May 31, 2011
Last modified: February 19, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families