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Protein

Xylose isomerase

Gene

xylA

Organism
Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei100UniRule annotation1
Active sitei103UniRule annotation1
Metal bindingi231Magnesium 1UniRule annotation1
Metal bindingi267Magnesium 1UniRule annotation1
Metal bindingi267Magnesium 2UniRule annotation1
Metal bindingi270Magnesium 2UniRule annotation1
Metal bindingi295Magnesium 1UniRule annotation1
Metal bindingi306Magnesium 2UniRule annotation1
Metal bindingi308Magnesium 2UniRule annotation1
Metal bindingi338Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Tresu_1283Imported
OrganismiTreponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091)Imported
Taxonomic identifieri869209 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000006852 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi869209.Tresu_1283.

Structurei

3D structure databases

ProteinModelPortaliF2NRV5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C93. Bacteria.
COG2115. LUCA.
KOiK01805.
OMAiHTFQHEL.
OrthoDBiPOG091H07LC.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F2NRV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFFKGSKEY FPGIGQIKYE GPESKNPLAF KYYDAEKVVM GKKMKDWLKF
60 70 80 90 100
TVAYWHSFCA DGGDPFGSGT REFTWKTPEE KVDAAFEFIT KLGCGYYAWH
110 120 130 140 150
DRDICPEGTS PADSEKKLSH ITDLLLERQK ETGVKLLWGT ANVFNNPRYM
160 170 180 190 200
NGAATNPDFD VVAQAASQIK AAIDNTIKLG GAGYTFWGGR EGYMSLLNTD
210 220 230 240 250
MKAEKEHLAM MLTLARDYAR KQGFTGCFYI EPKPMEPTKH QYDYDSETVI
260 270 280 290 300
GFLRAHGLDK DFKLNIEANH AELAGHEFAH ELTVCVDNGM LGSIDANRGD
310 320 330 340 350
PVNGWDTDQF PVSIYETTQA MLQVIRMGGF TTGGLNFDAK VRRNSVAPED
360 370 380 390 400
LFIAHIGGMD IFARGLEKAV QLIEDRRIPS MLKERYASFE TGNGKAFAEG
410 420 430
KLTLDQVASL AKPYEQVAKT SGKQELYENI LNQICLG
Length:437
Mass (Da):48,833
Last modified:May 31, 2011 - v1
Checksum:i8AC37EE4E50936AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002631 Genomic DNA. Translation: AEB14191.1.
RefSeqiWP_013701478.1. NC_015385.1.

Genome annotation databases

EnsemblBacteriaiAEB14191; AEB14191; Tresu_1283.
KEGGitsu:Tresu_1283.
PATRICi54429232. VBITreSuc166698_1349.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002631 Genomic DNA. Translation: AEB14191.1.
RefSeqiWP_013701478.1. NC_015385.1.

3D structure databases

ProteinModelPortaliF2NRV5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi869209.Tresu_1283.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEB14191; AEB14191; Tresu_1283.
KEGGitsu:Tresu_1283.
PATRICi54429232. VBITreSuc166698_1349.

Phylogenomic databases

eggNOGiENOG4105C93. Bacteria.
COG2115. LUCA.
KOiK01805.
OMAiHTFQHEL.
OrthoDBiPOG091H07LC.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF2NRV5_TRES6
AccessioniPrimary (citable) accession number: F2NRV5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: November 30, 2016
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.