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F2NRV5

- F2NRV5_TRES6

UniProt

F2NRV5 - F2NRV5_TRES6

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Protein

Xylose isomerase

Gene
xylA, Tresu_1283
Organism
Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei100 – 1001 By similarityUniRule annotation
Active sitei103 – 1031 By similarityUniRule annotation
Metal bindingi231 – 2311Magnesium 1 By similarityUniRule annotation
Metal bindingi267 – 2671Magnesium 1 By similarityUniRule annotation
Metal bindingi267 – 2671Magnesium 2 By similarityUniRule annotation
Metal bindingi270 – 2701Magnesium 2 By similarityUniRule annotation
Metal bindingi295 – 2951Magnesium 1 By similarityUniRule annotation
Metal bindingi306 – 3061Magnesium 2 By similarityUniRule annotation
Metal bindingi308 – 3081Magnesium 2 By similarityUniRule annotation
Metal bindingi338 – 3381Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotations, Xylose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciTSUC869209:GHSS-1311-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Tresu_1283Imported
OrganismiTreponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091)Imported
Taxonomic identifieri869209 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000006852: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliF2NRV5.

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.
OMAiLFHAHIG.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F2NRV5-1 [UniParc]FASTAAdd to Basket

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MSFFKGSKEY FPGIGQIKYE GPESKNPLAF KYYDAEKVVM GKKMKDWLKF    50
TVAYWHSFCA DGGDPFGSGT REFTWKTPEE KVDAAFEFIT KLGCGYYAWH 100
DRDICPEGTS PADSEKKLSH ITDLLLERQK ETGVKLLWGT ANVFNNPRYM 150
NGAATNPDFD VVAQAASQIK AAIDNTIKLG GAGYTFWGGR EGYMSLLNTD 200
MKAEKEHLAM MLTLARDYAR KQGFTGCFYI EPKPMEPTKH QYDYDSETVI 250
GFLRAHGLDK DFKLNIEANH AELAGHEFAH ELTVCVDNGM LGSIDANRGD 300
PVNGWDTDQF PVSIYETTQA MLQVIRMGGF TTGGLNFDAK VRRNSVAPED 350
LFIAHIGGMD IFARGLEKAV QLIEDRRIPS MLKERYASFE TGNGKAFAEG 400
KLTLDQVASL AKPYEQVAKT SGKQELYENI LNQICLG 437
Length:437
Mass (Da):48,833
Last modified:May 31, 2011 - v1
Checksum:i8AC37EE4E50936AF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002631 Genomic DNA. Translation: AEB14191.1.
RefSeqiYP_004365488.1. NC_015385.1.

Genome annotation databases

EnsemblBacteriaiAEB14191; AEB14191; Tresu_1283.
GeneIDi10431398.
KEGGitsu:Tresu_1283.
PATRICi54429232. VBITreSuc166698_1349.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002631 Genomic DNA. Translation: AEB14191.1 .
RefSeqi YP_004365488.1. NC_015385.1.

3D structure databases

ProteinModelPortali F2NRV5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEB14191 ; AEB14191 ; Tresu_1283 .
GeneIDi 10431398.
KEGGi tsu:Tresu_1283.
PATRICi 54429232. VBITreSuc166698_1349.

Phylogenomic databases

KOi K01805.
OMAi LFHAHIG.

Enzyme and pathway databases

BioCyci TSUC869209:GHSS-1311-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome of chromosome of Treponema succinifaciens DSM 2489."
    Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L., Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Teshima H., Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.
    , Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P., Eisen J.A.
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33096 / DSM 2489 / 6091.

Entry informationi

Entry nameiF2NRV5_TRES6
AccessioniPrimary (citable) accession number: F2NRV5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: June 11, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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