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F2NRV5

- F2NRV5_TRES6

UniProt

F2NRV5 - F2NRV5_TRES6

Protein

Xylose isomerase

Gene

xylA

Organism
Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 23 (01 Oct 2014)
      Sequence version 1 (31 May 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

    Cofactori

    Binds 2 magnesium ions per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei100 – 1001UniRule annotation
    Active sitei103 – 1031UniRule annotation
    Metal bindingi231 – 2311Magnesium 1UniRule annotation
    Metal bindingi267 – 2671Magnesium 1UniRule annotation
    Metal bindingi267 – 2671Magnesium 2UniRule annotation
    Metal bindingi270 – 2701Magnesium 2UniRule annotation
    Metal bindingi295 – 2951Magnesium 1UniRule annotation
    Metal bindingi306 – 3061Magnesium 2UniRule annotation
    Metal bindingi308 – 3081Magnesium 2UniRule annotation
    Metal bindingi338 – 3381Magnesium 1UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. xylose isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-xylose metabolic process Source: UniProtKB-HAMAP
    2. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciTSUC869209:GHSS-1311-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
    Gene namesi
    Name:xylAUniRule annotation
    Ordered Locus Names:Tresu_1283Imported
    OrganismiTreponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091)Imported
    Taxonomic identifieri869209 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
    ProteomesiUP000006852: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliF2NRV5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the xylose isomerase family.UniRule annotation

    Phylogenomic databases

    KOiK01805.
    OMAiLFHAHIG.

    Family and domain databases

    Gene3Di3.20.20.150. 1 hit.
    HAMAPiMF_00455. Xylose_isom_A.
    InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view]
    PfamiPF01261. AP_endonuc_2. 1 hit.
    [Graphical view]
    PRINTSiPR00688. XYLOSISMRASE.
    SUPFAMiSSF51658. SSF51658. 1 hit.
    TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
    PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F2NRV5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSFFKGSKEY FPGIGQIKYE GPESKNPLAF KYYDAEKVVM GKKMKDWLKF    50
    TVAYWHSFCA DGGDPFGSGT REFTWKTPEE KVDAAFEFIT KLGCGYYAWH 100
    DRDICPEGTS PADSEKKLSH ITDLLLERQK ETGVKLLWGT ANVFNNPRYM 150
    NGAATNPDFD VVAQAASQIK AAIDNTIKLG GAGYTFWGGR EGYMSLLNTD 200
    MKAEKEHLAM MLTLARDYAR KQGFTGCFYI EPKPMEPTKH QYDYDSETVI 250
    GFLRAHGLDK DFKLNIEANH AELAGHEFAH ELTVCVDNGM LGSIDANRGD 300
    PVNGWDTDQF PVSIYETTQA MLQVIRMGGF TTGGLNFDAK VRRNSVAPED 350
    LFIAHIGGMD IFARGLEKAV QLIEDRRIPS MLKERYASFE TGNGKAFAEG 400
    KLTLDQVASL AKPYEQVAKT SGKQELYENI LNQICLG 437
    Length:437
    Mass (Da):48,833
    Last modified:May 31, 2011 - v1
    Checksum:i8AC37EE4E50936AF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002631 Genomic DNA. Translation: AEB14191.1.
    RefSeqiYP_004365488.1. NC_015385.1.

    Genome annotation databases

    EnsemblBacteriaiAEB14191; AEB14191; Tresu_1283.
    GeneIDi10431398.
    KEGGitsu:Tresu_1283.
    PATRICi54429232. VBITreSuc166698_1349.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002631 Genomic DNA. Translation: AEB14191.1 .
    RefSeqi YP_004365488.1. NC_015385.1.

    3D structure databases

    ProteinModelPortali F2NRV5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEB14191 ; AEB14191 ; Tresu_1283 .
    GeneIDi 10431398.
    KEGGi tsu:Tresu_1283.
    PATRICi 54429232. VBITreSuc166698_1349.

    Phylogenomic databases

    KOi K01805.
    OMAi LFHAHIG.

    Enzyme and pathway databases

    BioCyci TSUC869209:GHSS-1311-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.150. 1 hit.
    HAMAPi MF_00455. Xylose_isom_A.
    InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view ]
    Pfami PF01261. AP_endonuc_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00688. XYLOSISMRASE.
    SUPFAMi SSF51658. SSF51658. 1 hit.
    TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
    PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome of chromosome of Treponema succinifaciens DSM 2489."
      Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L., Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Teshima H., Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.
      , Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P., Eisen J.A.
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33096 / DSM 2489 / 6091Imported.

    Entry informationi

    Entry nameiF2NRV5_TRES6
    AccessioniPrimary (citable) accession number: F2NRV5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 31, 2011
    Last sequence update: May 31, 2011
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3