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F2NRV5

- F2NRV5_TRES6

UniProt

F2NRV5 - F2NRV5_TRES6

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Protein

Xylose isomerase

Gene

xylA

Organism
Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei100 – 1001UniRule annotation
Active sitei103 – 1031UniRule annotation
Metal bindingi231 – 2311Magnesium 1UniRule annotation
Metal bindingi267 – 2671Magnesium 1UniRule annotation
Metal bindingi267 – 2671Magnesium 2UniRule annotation
Metal bindingi270 – 2701Magnesium 2UniRule annotation
Metal bindingi295 – 2951Magnesium 1UniRule annotation
Metal bindingi306 – 3061Magnesium 2UniRule annotation
Metal bindingi308 – 3081Magnesium 2UniRule annotation
Metal bindingi338 – 3381Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciTSUC869209:GHSS-1311-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Tresu_1283Imported
OrganismiTreponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091)Imported
Taxonomic identifieri869209 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000006852: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliF2NRV5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.
OMAiLFHAHIG.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F2NRV5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSFFKGSKEY FPGIGQIKYE GPESKNPLAF KYYDAEKVVM GKKMKDWLKF
60 70 80 90 100
TVAYWHSFCA DGGDPFGSGT REFTWKTPEE KVDAAFEFIT KLGCGYYAWH
110 120 130 140 150
DRDICPEGTS PADSEKKLSH ITDLLLERQK ETGVKLLWGT ANVFNNPRYM
160 170 180 190 200
NGAATNPDFD VVAQAASQIK AAIDNTIKLG GAGYTFWGGR EGYMSLLNTD
210 220 230 240 250
MKAEKEHLAM MLTLARDYAR KQGFTGCFYI EPKPMEPTKH QYDYDSETVI
260 270 280 290 300
GFLRAHGLDK DFKLNIEANH AELAGHEFAH ELTVCVDNGM LGSIDANRGD
310 320 330 340 350
PVNGWDTDQF PVSIYETTQA MLQVIRMGGF TTGGLNFDAK VRRNSVAPED
360 370 380 390 400
LFIAHIGGMD IFARGLEKAV QLIEDRRIPS MLKERYASFE TGNGKAFAEG
410 420 430
KLTLDQVASL AKPYEQVAKT SGKQELYENI LNQICLG
Length:437
Mass (Da):48,833
Last modified:May 31, 2011 - v1
Checksum:i8AC37EE4E50936AF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002631 Genomic DNA. Translation: AEB14191.1.
RefSeqiWP_013701478.1. NC_015385.1.
YP_004365488.1. NC_015385.1.

Genome annotation databases

EnsemblBacteriaiAEB14191; AEB14191; Tresu_1283.
GeneIDi10431398.
KEGGitsu:Tresu_1283.
PATRICi54429232. VBITreSuc166698_1349.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002631 Genomic DNA. Translation: AEB14191.1 .
RefSeqi WP_013701478.1. NC_015385.1.
YP_004365488.1. NC_015385.1.

3D structure databases

ProteinModelPortali F2NRV5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEB14191 ; AEB14191 ; Tresu_1283 .
GeneIDi 10431398.
KEGGi tsu:Tresu_1283.
PATRICi 54429232. VBITreSuc166698_1349.

Phylogenomic databases

KOi K01805.
OMAi LFHAHIG.

Enzyme and pathway databases

BioCyci TSUC869209:GHSS-1311-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome of chromosome of Treponema succinifaciens DSM 2489."
    Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L., Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Teshima H., Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.
    , Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P., Eisen J.A.
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33096 / DSM 2489 / 6091Imported.

Entry informationi

Entry nameiF2NRV5_TRES6
AccessioniPrimary (citable) accession number: F2NRV5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: October 29, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3