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F2NP43

- F2NP43_MARHT

UniProt

F2NP43 - F2NP43_MARHT

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Marinithermus hydrothermalis (strain DSM 14884 / JCM 11576 / T1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei145 – 1451UniRule annotation
Active sitei551 – 5511UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMHYD869210:GHEE-913-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Marky_0885Imported
OrganismiMarinithermus hydrothermalis (strain DSM 14884 / JCM 11576 / T1)Imported
Taxonomic identifieri869210 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeMarinithermus
ProteomesiUP000007030: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F2NP43-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDAFGVLKRE VDRLGRALGH AIRTLSGKKL FDLEEEVRAL TKHLRAHPED
60 70 80 90 100
AAARARLEAR IRSLSLDEAE GLVRAFSTYF HLVNLAEDRH RVRVNRLRDA
110 120 130 140 150
EATPDAPRPE SLMGLVGELK KRGFSAEEAA ALLRKVRLHL TFTAHPTETR
160 170 180 190 200
RRTVRHHLQA IARLLEQLEQ GAAPQEALEA RVCLLWGTQE LRKTQPSVTD
210 220 230 240 250
EVKGGLYYLQ TTLWEALPRL VEGLERAFQV HYGTRVALEP PVRFRSWIGG
260 270 280 290 300
DRDGNPNVTP EVTAWAQHHA RARLIQRYLE ALDGLVQALS LAEERVPVPR
310 320 330 340 350
ELRLVAEGWA ERLGLPKRFL GEPYRRYLMA LHRRLRGTLG EPNGEAYSTP
360 370 380 390 400
QAFVEDLERV ERGLFQIGLD AVVRTMVRPL TLRAKTYGLD LVALDLREEA
410 420 430 440 450
QQHAEAVAEL LEAAGVTADY RERPPESREA LLTAELASAR PLAPVGYSPR
460 470 480 490 500
TRALRVALEA LRAWRAYGGY VISMAQHPAD ALEVFVLARE VGLYRPGQAL
510 520 530 540 550
PFDVVPLFET LADLERAPGV VARLLENPVF RAHVKARGGL EVMIGYSDSN
560 570 580 590 600
KDAGFLAANW ALYRAQEGIA RVARAAGVPV FFFHGRGTST ARGGAPAGRA
610 620 630 640 650
IAALPWGTVG MRMRLTEQGE ALADRYAHAE LALRHLEQLL YHFVLAAARD
660 670 680 690 700
LRGEGDPPPK AWLEAMDRAA ARAAEVYRAL LAAPGFFEFY EALTPIREIA
710 720 730 740 750
DLKIASRPVY RHGRVREIRD LRAIPWVMSW AQVRANLPGW FGLGSGLEVL
760 770 780 790 800
PLELRRAMYR GWPFFASVLE SAAVSLAKAD LGITRSYLRL VPEALAQRFF
810 820 830 840 850
PVIEAEFAKS RRLLEETFDR PLLWNQQTLA RSIALRNPYV DPISHVQAEL
860 870 880
LARYRSAPPD APERAQLERA LLASLLGIAA GLRNTG
Length:886
Mass (Da):98,965
Last modified:May 31, 2011 - v1
Checksum:i3C170F4FEFCCBD5B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002630 Genomic DNA. Translation: AEB11631.1.
RefSeqiWP_013703681.1. NC_015387.1.
YP_004367741.1. NC_015387.1.

Genome annotation databases

EnsemblBacteriaiAEB11631; AEB11631; Marky_0885.
GeneIDi10433783.
KEGGimhd:Marky_0885.
PATRICi54434136. VBIMarHyd166763_0882.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002630 Genomic DNA. Translation: AEB11631.1 .
RefSeqi WP_013703681.1. NC_015387.1.
YP_004367741.1. NC_015387.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEB11631 ; AEB11631 ; Marky_0885 .
GeneIDi 10433783.
KEGGi mhd:Marky_0885.
PATRICi 54434136. VBIMarHyd166763_0882.

Phylogenomic databases

KOi K01595.

Enzyme and pathway databases

BioCyci MHYD869210:GHEE-913-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 14884 / JCM 11576 / T1Imported.

Entry informationi

Entry nameiF2NP43_MARHT
AccessioniPrimary (citable) accession number: F2NP43
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: October 29, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3