F2NL98 (F2NL98_MARHT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Uridine kinase RuleBase RU003825 HAMAP-Rule MF_00551
EC=2.7.1.48 RuleBase RU003825 HAMAP-Rule MF_00551

Alternative name(s):
Cytidine monophosphokinase HAMAP-Rule MF_00551
Uridine monophosphokinase HAMAP-Rule MF_00551

Gene names

Name:	udk HAMAP-Rule MF_00551
Ordered Locus Names:	Marky_0973

Organism

Marinithermus hydrothermalis (strain DSM 14884 / JCM 11576 / T1) [Complete proteome] [HAMAP] EMBL AEB11717.1

Taxonomic identifier

869210 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Marinithermus › Marinithermus hydrothermalis

Protein attributes

Sequence length	205 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + cytidine = ADP + CMP. RuleBase RU003825 HAMAP-Rule MF_00551 ATP + uridine = ADP + UMP. RuleBase RU003825 HAMAP-Rule MF_00551
Pathway	Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3. RuleBase RU003825 HAMAP-Rule MF_00551 Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1. RuleBase RU003825 HAMAP-Rule MF_00551
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00551.
Sequence similarities	Belongs to the uridine kinase family. HAMAP-Rule MF_00551 RuleBase RU003824

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP-Rule MF_00551
Ligand	ATP-binding HAMAP-Rule MF_00551 RuleBase RU003528 SAAS SAAS000764 Nucleotide-binding
Molecular function	Kinase HAMAP-Rule MF_00551 RuleBase RU003528 SAAS SAAS000764 EMBL AEB11717.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	CTP salvage Inferred from electronic annotation. Source: UniProtKB-UniPathway UMP salvage Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP phosphotransferase activity, alcohol group as acceptor Inferred from electronic annotation. Source: InterPro uridine kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	10 – 17	8	ATP By similarity HAMAP-Rule MF_00551

Sequences

	Sequence		Length	Mass (Da)
	F2NL98 [UniParc]. Last modified May 31, 2011. Version 1. Checksum: DECDC375521332AC	FASTA	205	23,475
	10 20 30 40 50 60 MKPFVIGIAG GTGSGKTTVT ERVIETVGRD RVALVPMDNY YKDQSHLPFE ERTRINYDHP 70 80 90 100 110 120 AAFDTGLLLE HLEALMNGVP IEMPLYSFTE HVRLLETATV APAPVVVIEG ILALYDEHLR 130 140 150 160 170 180 RLMDLKVFVD ADPDVRFIRR LERDIRERGR TLESVIRQYL EFVRPMHLSF VEPTKRYADV 190 200 IIPRGGHNQP ALEMLVSRIR TLIEV

References

[1]

"Complete genome sequence of the aerobic, heterotroph Marinithermus hydrothermalis type strain (T1(T)) from a deep-sea hydrothermal vent chimney." Copeland A., Gu W., Yasawong M., Lapidus A., Lucas S., Deshpande S., Pagani I., Tapia R., Cheng J.F., Goodwin L.A., Pitluck S., Liolios K., Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K. , Land M., Pan C., Brambilla E.M., Rohde M., Tindall B.J., Sikorski J., Goker M., Detter J.C., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Woyke T. Stand. Genomic Sci. 6:21-30(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14884 / JCM 11576 / T1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002630 Genomic DNA. Translation: AEB11717.1.
RefSeq	YP_004367827.1. NC_015387.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEB11717; AEB11717; Marky_0973.
GeneID	10433871.
KEGG	mhd:Marky_0973.
PATRIC	54434306. VBIMarHyd166763_0967.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K00876.
Enzyme and pathway databases
BioCyc	MHYD869210:GHEE-1000-MONOMER.
UniPathway	UPA00574; UER00637. UPA00579; UER00640.
Family and domain databases
HAMAP	MF_00551. Uridine_kinase.
InterPro	IPR006083. PRK/URK. IPR000764. Uridine_kinase. [Graphical view]
Pfam	PF00485. PRK. 1 hit. [Graphical view]
PRINTS	PR00988. URIDINKINASE.
TIGRFAMs	TIGR00235. udk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F2NL98_MARHT

Accession

Primary (citable) accession number: F2NL98

Entry history

Integrated into UniProtKB/TrEMBL:	May 31, 2011
Last sequence update:	May 31, 2011
Last modified:	April 3, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)