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F2NGB8 (F2NGB8_DESAR) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate dehydratase HAMAP-Rule MF_00214
Short name=3-dehydroquinase HAMAP-Rule MF_00214
EC=4.2.1.10 HAMAP-Rule MF_00214
Alternative name(s):
Type I DHQase HAMAP-Rule MF_00214
Gene names
Name:aroD HAMAP-Rule MF_00214
Ordered Locus Names:Desac_0649 EMBL AEB08531.1
OrganismDesulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2) [Complete proteome] [HAMAP] EMBL AEB08531.1
Taxonomic identifier880072 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Syntrophobacterales › Syntrophaceae › Desulfobacca ›

Protein attributes

Sequence length225 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-dehydroquinate = 3-dehydroshikimate + H2O. HAMAP-Rule MF_00214

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7. HAMAP-Rule MF_00214

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00214

Sequence similarities

Belongs to the type-I 3-dehydroquinase family. HAMAP-Rule MF_00214

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region33 – 353Substrate binding By similarity HAMAP-Rule MF_00214

Sites

Active site1181Proton donor/acceptor By similarity HAMAP-Rule MF_00214
Active site1451Schiff-base intermediate with substrate By similarity HAMAP-Rule MF_00214
Binding site601Substrate By similarity HAMAP-Rule MF_00214
Binding site1861Substrate By similarity HAMAP-Rule MF_00214
Binding site2071Substrate By similarity HAMAP-Rule MF_00214
Binding site2111Substrate By similarity HAMAP-Rule MF_00214

Sequences

Sequence LengthMass (Da)Tools
F2NGB8 [UniParc].

Last modified May 31, 2011. Version 1.
Checksum: 31CB6DD419E89AAC

FASTA22524,686
        10         20         30         40         50         60 
MSSIRICIPV VETDCDAACQ CLARIHAQGF LAELRLDYLI QPDLQHLLHA PRGPVIATNR 

        70         80         90        100        110        120 
LPNEGGRFSG PESARRRLLE QAIDLGADYV DVEFNADPFW RNDLLAHRGA VKLILSWHDF 

       130        140        150        160        170        180 
KGPSTPPRLH EIMTAMIDCG ADIIKLVTYA HHPSDCLALL GLIPAAQQQG QDIIAFCMGS 

       190        200        210        220 
AGKYSRVIAP LLGSYLTFAV LEAGKESAPG QLTVQEMTSI WEMLT

« Hide

References

[1]"The complete genome of Desulfobacca acetoxidans DSM 11109."
US DOE Joint Genome Institute (JGI-PGF)
Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L., Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Teshima H., Detter J.C., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F. expand/collapse author list , Hugenholtz P., Woyke T., Wu D., Spring S., Schueler E., Brambilla E., Klenk H.-P., Eisen J.A.
Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700848 / DSM 11109 / ASRB2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002629 Genomic DNA. Translation: AEB08531.1.
RefSeqYP_004369712.1. NC_015388.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEB08531; AEB08531; Desac_0649.
GeneID10435842.
KEGGdao:Desac_0649.
PATRIC54438392. VBIDesAce170587_0709.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK03785.

Enzyme and pathway databases

BioCycDACE880072:GHK9-660-MONOMER.
UniPathwayUPA00053; UER00086.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00214. AroD.
InterProIPR013785. Aldolase_TIM.
IPR001381. DHquinase_I.
[Graphical view]
PfamPF01487. DHquinase_I. 1 hit.
[Graphical view]
TIGRFAMsTIGR01093. aroD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF2NGB8_DESAR
AccessionPrimary (citable) accession number: F2NGB8
Entry history
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: May 1, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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