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F2NAE0

- F2NAE0_CORGP

UniProt

F2NAE0 - F2NAE0_CORGP

Protein

Alanine racemase

Gene

Corgl_0199

Organism
Coriobacterium glomerans (strain ATCC 49209 / DSM 20642 / JCM 10262 / PW2)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (31 May 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei43 – 431Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei141 – 1411SubstrateUniRule annotation
    Active sitei270 – 2701Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei319 – 3191Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciCGLO700015:GH6A-207-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Corgl_0199Imported
    OrganismiCoriobacterium glomerans (strain ATCC 49209 / DSM 20642 / JCM 10262 / PW2)Imported
    Taxonomic identifieri700015 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaCoriobacteridaeCoriobacterialesCoriobacterineaeCoriobacteriaceaeCoriobacterium
    ProteomesiUP000006851: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei43 – 431N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliF2NAE0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.
    OMAiLWQLEAI.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F2NAE0-1 [UniParc]FASTAAdd to Basket

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    MVPAGGPATR WAWVEIDRGA MLRNTRAFKK MLKPRQRLCC VLKADAYGHG    50
    AVESSKIMRS AGADMFAVAT VAEGIELRRG GCSAPVLVLG EPPCDAIPEL 100
    LENDLMPAVY TSEFALAFGE CAVQVDKVGK YHLAIETGMN RIGVHYTKVV 150
    SFRRGIEFHR GIQCDGVFTH FATADDPCGW DYKLQCTRFD EAVQAMRDAG 200
    FECGIVHCDN TPASILDPES HHDMIRVGIG LYGLQPADAT RERIRLDPVM 250
    SVRARVMRVA YPSMGEGVGY GFTYRVPRAT VQICTLPIGY ADGLARTLSN 300
    RMDVLYRGGR IRQVGNICMD QTMVAIQQTP AEPIPEAEYG DLMTIVGRDG 350
    DAEVSMDEMA RLRNTINYEV ACDFGMRLEK IYI 383
    Length:383
    Mass (Da):42,291
    Last modified:May 31, 2011 - v1
    Checksum:iB49A55AE569D3566
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002628 Genomic DNA. Translation: AEB06326.1.
    RefSeqiWP_013708069.1. NC_015389.1.
    YP_004372141.1. NC_015389.1.

    Genome annotation databases

    EnsemblBacteriaiAEB06326; AEB06326; Corgl_0199.
    GeneIDi10438413.
    KEGGicgo:Corgl_0199.
    PATRICi54443843. VBICorGlo157054_0209.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002628 Genomic DNA. Translation: AEB06326.1 .
    RefSeqi WP_013708069.1. NC_015389.1.
    YP_004372141.1. NC_015389.1.

    3D structure databases

    ProteinModelPortali F2NAE0.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEB06326 ; AEB06326 ; Corgl_0199 .
    GeneIDi 10438413.
    KEGGi cgo:Corgl_0199.
    PATRICi 54443843. VBICorGlo157054_0209.

    Phylogenomic databases

    KOi K01775.
    OMAi LWQLEAI.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci CGLO700015:GH6A-207-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: ATCC 49209 / DSM 20642 / JCM 10262 / PW2Imported.

    Entry informationi

    Entry nameiF2NAE0_CORGP
    AccessioniPrimary (citable) accession number: F2NAE0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 31, 2011
    Last sequence update: May 31, 2011
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3