Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

F2N9E1 (F2N9E1_CORGP) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Corgl_1794 EMBL AEB07889.1
OrganismCoriobacterium glomerans (strain ATCC 49209 / DSM 20642 / JCM 10262 / PW2) [Complete proteome] [HAMAP] EMBL AEB07889.1
Taxonomic identifier700015 [NCBI]
Taxonomic lineageBacteriaActinobacteriaCoriobacteridaeCoriobacterialesCoriobacterineaeCoriobacteriaceaeCoriobacterium

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain109 – 310202ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding137 – 19256ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2651Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2771Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2771Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2791Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
F2N9E1 [UniParc].

Last modified May 31, 2011. Version 1.
Checksum: CE1BC9F727FBA87D

FASTA31833,851
        10         20         30         40         50         60 
MPISRRESMS IAVLAGGTSP EREISFASGE SVCRALKQAG YGRVETLDPA DSGFLKEIES 

        70         80         90        100        110        120 
ASFDAVFIAL HGAGGEDGTI QGVLDYLHIP YTGSGVRASA CAADKDVSKI IFEHAGIPVA 

       130        140        150        160        170        180 
RGVTLCRGDE LNPDSLVAEL GKECFVKPAM NGSSLGVSLI RHPSELPKAV ERAFESSDKV 

       190        200        210        220        230        240 
LIEQRLIGTE ISVGVLGGRD AKALPVVEIM GQEGTDFYNK EVKYIDPALV HRIPARLPTG 

       250        260        270        280        290        300 
ICETAGALAL GAHRALGCYG FSRSDFIVTE EGPVILETNT IPGMTEASLF PDEIRHCGRT 

       310 
FAEACDEMIM LALQRVRA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002628 Genomic DNA. Translation: AEB07889.1.
RefSeqYP_004373704.1. NC_015389.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEB07889; AEB07889; Corgl_1794.
GeneID10440054.
KEGGcgo:Corgl_1794.
PATRIC54447375. VBICorGlo157054_1927.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycCGLO700015:GH6A-1848-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF2N9E1_CORGP
AccessionPrimary (citable) accession number: F2N9E1
Entry history
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: March 19, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)