Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Thymidine kinase

Gene

tdk

Organism
Lactobacillus amylovorus (strain GRL 1118)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei94Proton acceptorUniRule annotation1
Metal bindingi151ZincUniRule annotation1
Metal bindingi154ZincUniRule annotation1
Metal bindingi188ZincUniRule annotation1
Metal bindingi191ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi9 – 16ATPUniRule annotation8
Nucleotide bindingi93 – 96ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:LAB52_03790Imported
OrganismiLactobacillus amylovorus (strain GRL 1118)Imported
Taxonomic identifieri695562 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000008140 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857
OMAiKEQFGWI

Family and domain databases

HAMAPiMF_00124 Thymidine_kinase, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
IPR020633 Thymidine_kinase_CS
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00603 TK_CELLULAR_TYPE, 1 hit

Sequencei

Sequence statusi: Complete.

F2LYS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQLFFRYGA MSSGKTIEIL KVAHNYEAQG RRIALMTSGL DNRSGVGTVA
60 70 80 90 100
SRIGLHRKAI PITSEMNLFE YIKKMNDHDL ADGDGKLACV LIDEAQFLKR
110 120 130 140 150
HHVLECAKIV DDFNIPVMTF GLKNDFQNHL FEGSENLLIF ADKIEEMKTI
160 170 180 190
CHYCGHKATM NLRVNNGKPV YEGEQVQIGG DESYYPVCRY HYFHPGSKR
Length:199
Mass (Da):22,576
Last modified:May 31, 2011 - v1
Checksum:i9FB40612A8C96756
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002609 Genomic DNA Translation: AEA31728.1
RefSeqiWP_013437578.1, NC_017470.1

Genome annotation databases

EnsemblBacteriaiAEA31728; AEA31728; LAB52_03790
GeneIDi31801892
KEGGilay:LAB52_03790
PATRICifig|695562.4.peg.748

Similar proteinsi

Entry informationi

Entry nameiF2LYS5_LACAL
AccessioniPrimary (citable) accession number: F2LYS5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: April 25, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health