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F2LG33

- F2LG33_BURGS

UniProt

F2LG33 - F2LG33_BURGS

Protein

Alanine racemase

Gene

bgla_1g25870

Organism
Burkholderia gladioli (strain BSR3)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (31 May 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei35 – 351Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei130 – 1301SubstrateUniRule annotation
    Active sitei253 – 2531Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei301 – 3011Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciBGLA999541:GHSQ-2629-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:bgla_1g25870Imported
    OrganismiBurkholderia gladioli (strain BSR3)Imported
    Taxonomic identifieri999541 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
    ProteomesiUP000008316: Chromosome 1

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei35 – 351N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliF2LG33.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.
    OMAiNIRADEM.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F2LG33-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPRPISATIH TAALVNNLAA ARRFAPRSKV WAVVKANAYG HGLARAFPGL    50
    RSTDGFGLLD LEEAVKLREL GWAGPILLLE GFFRSTDVDV IDRYSLTTTV 100
    HNDDQLRMLE TARLSKPINI QLKMNSGMNR LGYAPDKYRA AWERARTCPG 150
    IGQITLMTHF ADADGERGVA DQMAAFERGA EGIAGARSLA NSAAVMWHPD 200
    THGDWVRPGI LLYGASPSGR AADIAGAGLQ AAMTLGSELI AVQNIAKGQA 250
    VGYGGAFVAP AQMRIGVVAC GYADGYPRIA PEGTPIVVDG VRTRIVGRVS 300
    MDMITVDLTP VPGAGIGARV ELWGQALPID DVAASCSTVG YELMCAIASR 350
    VPVRAE 356
    Length:356
    Mass (Da):37,706
    Last modified:May 31, 2011 - v1
    Checksum:i81B0CD06474D82A4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002599 Genomic DNA. Translation: AEA61207.1.
    RefSeqiWP_013698534.1. NC_015381.1.
    YP_004361163.1. NC_015381.1.

    Genome annotation databases

    EnsemblBacteriaiAEA61207; AEA61207; bgla_1g25870.
    GeneIDi10479098.
    KEGGibgd:bgla_1g25870.
    PATRICi54503420. VBIBurGla188977_6181.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002599 Genomic DNA. Translation: AEA61207.1 .
    RefSeqi WP_013698534.1. NC_015381.1.
    YP_004361163.1. NC_015381.1.

    3D structure databases

    ProteinModelPortali F2LG33.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEA61207 ; AEA61207 ; bgla_1g25870 .
    GeneIDi 10479098.
    KEGGi bgd:bgla_1g25870.
    PATRICi 54503420. VBIBurGla188977_6181.

    Phylogenomic databases

    KOi K01775.
    OMAi NIRADEM.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci BGLA999541:GHSQ-2629-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BSR3Imported.

    Entry informationi

    Entry nameiF2LG33_BURGS
    AccessioniPrimary (citable) accession number: F2LG33
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 31, 2011
    Last sequence update: May 31, 2011
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3