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F2KPR9 (F2KPR9_ARCVS) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Tyrosine--tRNA ligase HAMAP-Rule MF_02008
EC=6.1.1.1 HAMAP-Rule MF_02008
Alternative name(s):
Tyrosyl-tRNA synthetase HAMAP-Rule MF_02008
Gene names
Name:tyrS HAMAP-Rule MF_02008
Ordered Locus Names:Arcve_1597
OrganismArchaeoglobus veneficus (strain DSM 11195 / SNP6) [Complete proteome] [HAMAP] EMBL AEA47597.1
Taxonomic identifier693661 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus ›

Protein attributes

Sequence length329 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr) By similarity. HAMAP-Rule MF_02008

Catalytic activity

ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr). HAMAP-Rule MF_02008

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_02008

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_02008.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. HAMAP-Rule MF_02008

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif41 – 499"HIGH" region By similarity HAMAP-Rule MF_02008
Motif214 – 2185"KMSKS" region By similarity HAMAP-Rule MF_02008

Sites

Binding site361Tyrosine By similarity HAMAP-Rule MF_02008
Binding site1581Tyrosine By similarity HAMAP-Rule MF_02008
Binding site1621Tyrosine By similarity HAMAP-Rule MF_02008
Binding site1651Tyrosine By similarity HAMAP-Rule MF_02008
Binding site1801Tyrosine By similarity HAMAP-Rule MF_02008
Binding site2171ATP By similarity HAMAP-Rule MF_02008

Sequences

Sequence LengthMass (Da)Tools
F2KPR9 [UniParc].

Last modified May 31, 2011. Version 1.
Checksum: DD4391318C946483

FASTA32937,430
        10         20         30         40         50         60 
MDIDSRVALV TRNAVEIVTE DELRTLLETN EKPRAYVGYE PSGEIHLGHL MTVNKLIDLQ 

        70         80         90        100        110        120 
NAGFDVVVLL ADVHAYLNEK GDFEEIERIA EYNKQAFIAL GLEENKTEFV LGSSYQLSRD 

       130        140        150        160        170        180 
YVLDVLKMAR ITTLNRARRS MDEVSRRKED PMVSQMVYPL MQALDIAHLK IDLAVGGMDQ 

       190        200        210        220        230        240 
RKIHMLAREN LPRLGYLSPV CLHTPILLGL DGQKMSSSKG NYISVRDSEE EVEKKLRKAY 

       250        260        270        280        290        300 
CPAGQVEDNP IIQIMQYHIF PRFEKVVVER DEKYGGDIEY NSFDELVSDF ASKKLHPADL 

       310        320 
KKAAAKYLNK LLEASRRKLA EFQAGCSCE

« Hide

References

[1]"The complete genome of Archaeoglobus veneficus SNP6."
US DOE Joint Genome Institute (JGI-PGF)
Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Mikhailova N., Lu M., Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V. expand/collapse author list , Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S., Brambilla E., Klenk H.-P., Eisen J.A.
Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SNP6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002588 Genomic DNA. Translation: AEA47597.1.
RefSeqYP_004342312.1. NC_015320.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEA47597; AEA47597; Arcve_1597.
GeneID10394722.
KEGGave:Arcve_1597.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01866.
OMAKIHMLAR.

Enzyme and pathway databases

BioCycAVEN693661:GHD5-1633-MONOMER.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_02008. Tyr_tRNA_synth_type3.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002307. Tyr-tRNA-ligase.
IPR023684. Tyr-tRNA-ligase_3.
IPR023617. Tyr-tRNA-ligase_arc/euk-type.
[Graphical view]
PfamPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PIRSFPIRSF006588. TyrRS_arch_euk. 1 hit.
PRINTSPR01040. TRNASYNTHTYR.
TIGRFAMsTIGR00234. tyrS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF2KPR9_ARCVS
AccessionPrimary (citable) accession number: F2KPR9
Entry history
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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