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Protein

Xylose isomerase

Gene

xylA

Organism
Pseudomonas brassicacearum (strain NFM421)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei100 – 1001UniRule annotation
Active sitei103 – 1031UniRule annotation
Metal bindingi231 – 2311Magnesium 1UniRule annotation
Metal bindingi267 – 2671Magnesium 1UniRule annotation
Metal bindingi267 – 2671Magnesium 2UniRule annotation
Metal bindingi270 – 2701Magnesium 2UniRule annotation
Metal bindingi295 – 2951Magnesium 1UniRule annotation
Metal bindingi306 – 3061Magnesium 2UniRule annotation
Metal bindingi308 – 3081Magnesium 2UniRule annotation
Metal bindingi338 – 3381Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciPBRA994484:GJWC-2800-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
ORF Names:PSEBR_a2597Imported
OrganismiPseudomonas brassicacearum (strain NFM421)Imported
Taxonomic identifieri994484 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000006692: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliF2KFZ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.
OMAiTYAKGLK.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F2KFZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYFPAVDKI RYEGPASDSP LAFRHYDANK LVLGKPMREH LRMAVCYWHT
60 70 80 90 100
FVWPGSDVFG AGTFKRPWQH AGDPMELATG KAEAAFEFFS KLGIDYYCFH
110 120 130 140 150
DTDVAPEGSS LKEYREHFAL MVDHLERHQE ETGIKLLWGT ANCFSNPRFA
160 170 180 190 200
AGAASNPDPQ VFACAAAQVF SAMNATQRLK GSNYVLWGGR EGYETLLNTD
210 220 230 240 250
LKREREQLGR FMRMVVEHKH KIGFKGDLLI EPKPQEPTKH QYDYDSATVF
260 270 280 290 300
GFLQQFGLEN EIKVNIEANH ATLAGHSFHH EIATAVSLGI FGSIDANRGD
310 320 330 340 350
PQNGWDTDQF PNSVEEMTLA TYEILKAGGF RNGGFNFDSK VRRQSLDELD
360 370 380 390 400
LFHGHVAAMD VLALALERAA AMVQNDQLQQ FKDQRYAGWQ QPFGKAVLAG
410 420 430
DFSLESLAEH AFTNELNPQA VSGRQEMLEN VVNRFIYP
Length:438
Mass (Da):49,316
Last modified:May 31, 2011 - v1
Checksum:i48F9674A96F6FDC6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002585 Genomic DNA. Translation: AEA68887.1.
RefSeqiWP_013693218.1. NC_015379.1.
YP_004353891.1. NC_015379.1.

Genome annotation databases

EnsemblBacteriaiAEA68887; AEA68887; PSEBR_a2597.
GeneIDi10471609.
KEGGipba:PSEBR_a2597.
PATRICi54512824. VBIPseBra188168_2765.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002585 Genomic DNA. Translation: AEA68887.1.
RefSeqiWP_013693218.1. NC_015379.1.
YP_004353891.1. NC_015379.1.

3D structure databases

ProteinModelPortaliF2KFZ1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEA68887; AEA68887; PSEBR_a2597.
GeneIDi10471609.
KEGGipba:PSEBR_a2597.
PATRICi54512824. VBIPseBra188168_2765.

Phylogenomic databases

KOiK01805.
OMAiTYAKGLK.

Enzyme and pathway databases

BioCyciPBRA994484:GJWC-2800-MONOMER.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete genome sequence of a beneficial plant root-associated bacterium, Pseudomonas brassicacearum."
    Ortet P., Barakat M., Lalaouna D., Fochesato S., Barbe V., Vacherie B., Santaella C., Heulin T., Achouak W.
    J. Bacteriol. 193:3146-3146(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NFM421Imported.
  2. "Complete Genome Sequence of a beneficial plant roots-associated bacterium Pseudomonas brassicacearum."
    Ortet P., Barakat M., Lalaouna D., Fochesato S., Barbe V., Santaella C., Heulin T., Achouak W.
    Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NFM421.

Entry informationi

Entry nameiF2KFZ1_PSEBN
AccessioniPrimary (citable) accession number: F2KFZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: March 4, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.