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Protein

Aldose 1-epimerase

Gene

PSEBR_a1887

Organism
Pseudomonas brassicacearum (strain NFM421)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi: hexose metabolism

This protein is involved in the pathway hexose metabolism, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway hexose metabolism and in Carbohydrate metabolism.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei207 – 2071Proton donorUniRule annotation
Binding sitei283 – 2831SubstrateUniRule annotation
Active sitei348 – 3481Proton acceptorUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

BioCyciPBRA994484:GJWC-2019-MONOMER.
UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
ORF Names:PSEBR_a1887Imported
OrganismiPseudomonas brassicacearum (strain NFM421)Imported
Taxonomic identifieri994484 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000006692 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 383359Aldose 1-epimeraseSequence analysisPRO_5003281127Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

KOiK01785.
OMAiSPNHPDW.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. GH-type_carb-bd.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F2K9P5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLESRQLLTA LGVSLMIATS ASHAAGLTNE RGAFGKTDDG TAVEKFVLRN
60 70 80 90 100
SHGMEATVIT YGGILQSLSV PDKHGKAADI VLGFDDVQGY QKNGSVYFGA
110 120 130 140 150
TIGRFGNRLA DGAFELDGKR YQVPQNDHGN SLHGGPQGFD KRVWKAQPHN
160 170 180 190 200
AKDSVGVTLT YLSADGEMGF PGALKTDVTY SLNEQNELRI EYKATTDKPT
210 220 230 240 250
VLNLTNHSYF NLAGAGNGDI LEQVATLHAA HYTPVTGKLI PTGELAPVAG
260 270 280 290 300
TPMDFTQPTA IGTHIKADHP QLKFAEPKQG GFDFNWALDA KGDVNKLAAE
310 320 330 340 350
VYDTDSGRRL QLYTTEPGVQ FYTSNFLDGT VKGKQGKVYP HWGAFTLETQ
360 370 380
HYPDSPNQPN FPSTRLDPGQ TYTQTMVLKF SAK
Length:383
Mass (Da):41,460
Last modified:May 31, 2011 - v1
Checksum:i5ED23177FD7859FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002585 Genomic DNA. Translation: AEA68107.1.
RefSeqiWP_003200080.1. NC_015379.1.

Genome annotation databases

EnsemblBacteriaiAEA68107; AEA68107; PSEBR_a1887.
KEGGipba:PSEBR_a1887.
PATRICi54511304. VBIPseBra188168_2010.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002585 Genomic DNA. Translation: AEA68107.1.
RefSeqiWP_003200080.1. NC_015379.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEA68107; AEA68107; PSEBR_a1887.
KEGGipba:PSEBR_a1887.
PATRICi54511304. VBIPseBra188168_2010.

Phylogenomic databases

KOiK01785.
OMAiSPNHPDW.

Enzyme and pathway databases

UniPathwayiUPA00242.
BioCyciPBRA994484:GJWC-2019-MONOMER.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. GH-type_carb-bd.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF2K9P5_PSEBN
AccessioniPrimary (citable) accession number: F2K9P5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: July 6, 2016
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.