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F2JWD6

- F2JWD6_MARM1

UniProt

F2JWD6 - F2JWD6_MARM1

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Marme_1336

Organism
Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 19 (01 Oct 2014)
      Sequence version 1 (31 May 2011)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei145 – 1451SubstrateUniRule annotation
    Sitei254 – 2541Critical for catalysisUniRule annotation
    Metal bindingi349 – 3491Magnesium or manganese
    Sitei419 – 4191Critical for catalysisUniRule annotation
    Binding sitei546 – 5461SubstrateUniRule annotation
    Metal bindingi547 – 5471Magnesium or manganese
    Metal bindingi551 – 5511Magnesium or manganese

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciMMED717774:GCPW-1368-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
    Gene namesi
    Ordered Locus Names:Marme_1336Imported
    OrganismiMarinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1)Imported
    Taxonomic identifieri717774 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesMarinomonas
    ProteomesiUP000001062: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliF2JWD6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni132 – 1398Substrate bindingUniRule annotation

    Phylogenomic databases

    KOiK00031.
    OMAiSIVKLMQ.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F2JWD6-1 [UniParc]FASTAAdd to Basket

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    MSKHTIYYTL TDEAPALATA SLLPIFQAFA KEADINLQLT DISLAARVLS    50
    LFTDRLPEDK QVEDGLSFLG ELTADPDANF IKLPNISASI PQLTATIKEL 100
    QSQGYEIPDY PEAPATDEEK EINSRYSKVL GSAVNPVLRQ GNSDRRAPAA 150
    VKGFARKHPH SMGKWQKTSQ THADYMRDGD FFSSEQSVTM DKAQEVRIEF 200
    VNKSGEVDVK KTLPLLEGEV LDGMRMSASK LRDFFEQSLQ EAKEAGIMWS 250
    LHVKATMMKV SHPIVFGHAV TVYYKEVWDK FGDLFDELGV NPNNGIGSVY 300
    DKIKTLPQST QDEILESIHD CYEHRPEIAM VDSVRGITNL HVPSDVIVDA 350
    SMPAMIRSSG KMWGRDGKTK DTKAVMPEST YARIYQEVIN FCKTNGAFDP 400
    TTMGTVPNVG LMAQKAEEYG SHDKTFEVQE NGTMRVRDAE GNVLMQHDVE 450
    KGDIWRACQT KDAPIKDWVK LGVTRARNSG TPAVFWLDAE RAHDNELRKK 500
    VKLYLQDHDL EGLEIHIMSY NEAIRFSMER MMRGQDTISV SGNVLRDYLT 550
    DLFPIMELGT SAKMLSIVPM LNGGGMYETG AGGSAPKHVQ QLQEENYLRW 600
    DSLGEFLATA VSFEELGIKQ DNAKAKVLAA ALDRATEQLL DNNKSPSRKV 650
    GDIDNRGSHF YLTMYWAQAL ATQTDDAELA DKFASVAKAL VENESKIVEE 700
    LNSVQGKDAG LEGYYHMDLD AVTKVMRPSA TFNEILAAI 739
    Length:739
    Mass (Da):82,315
    Last modified:May 31, 2011 - v1
    Checksum:iE7DAF5E2241CCA22
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002583 Genomic DNA. Translation: ADZ90609.1.
    RefSeqiYP_004312445.1. NC_015276.1.

    Genome annotation databases

    EnsemblBacteriaiADZ90609; ADZ90609; Marme_1336.
    GeneIDi10335396.
    KEGGimme:Marme_1336.
    PATRICi47227410. VBIMarMed159599_1384.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002583 Genomic DNA. Translation: ADZ90609.1 .
    RefSeqi YP_004312445.1. NC_015276.1.

    3D structure databases

    ProteinModelPortali F2JWD6.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADZ90609 ; ADZ90609 ; Marme_1336 .
    GeneIDi 10335396.
    KEGGi mme:Marme_1336.
    PATRICi 47227410. VBIMarMed159599_1384.

    Phylogenomic databases

    KOi K00031.
    OMAi SIVKLMQ.

    Enzyme and pathway databases

    BioCyci MMED717774:GCPW-1368-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1Imported.

    Entry informationi

    Entry nameiF2JWD6_MARM1
    AccessioniPrimary (citable) accession number: F2JWD6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 31, 2011
    Last sequence update: May 31, 2011
    Last modified: October 1, 2014
    This is version 19 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3