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F2JWD6

- F2JWD6_MARM1

UniProt

F2JWD6 - F2JWD6_MARM1

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Protein
Submitted name: Isocitrate dehydrogenase, NADP-dependent
Gene
Marme_1336
Organism
Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei145 – 1451Substrate By similarityUniRule annotation
Sitei254 – 2541Critical for catalysis By similarityUniRule annotation
Metal bindingi349 – 3491Magnesium or manganese By similarityUniRule annotation
Sitei419 – 4191Critical for catalysis By similarityUniRule annotation
Binding sitei546 – 5461Substrate By similarityUniRule annotation
Metal bindingi547 – 5471Magnesium or manganese By similarityUniRule annotation
Metal bindingi551 – 5511Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciMMED717774:GCPW-1368-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Marme_1336Imported
OrganismiMarinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1)Imported
Taxonomic identifieri717774 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesMarinomonas
ProteomesiUP000001062: Chromosome

Structurei

3D structure databases

ProteinModelPortaliF2JWD6.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni132 – 1398Substrate binding By similarityUniRule annotation

Phylogenomic databases

KOiK00031.
OMAiSIVKLMQ.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

F2JWD6-1 [UniParc]FASTAAdd to Basket

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MSKHTIYYTL TDEAPALATA SLLPIFQAFA KEADINLQLT DISLAARVLS    50
LFTDRLPEDK QVEDGLSFLG ELTADPDANF IKLPNISASI PQLTATIKEL 100
QSQGYEIPDY PEAPATDEEK EINSRYSKVL GSAVNPVLRQ GNSDRRAPAA 150
VKGFARKHPH SMGKWQKTSQ THADYMRDGD FFSSEQSVTM DKAQEVRIEF 200
VNKSGEVDVK KTLPLLEGEV LDGMRMSASK LRDFFEQSLQ EAKEAGIMWS 250
LHVKATMMKV SHPIVFGHAV TVYYKEVWDK FGDLFDELGV NPNNGIGSVY 300
DKIKTLPQST QDEILESIHD CYEHRPEIAM VDSVRGITNL HVPSDVIVDA 350
SMPAMIRSSG KMWGRDGKTK DTKAVMPEST YARIYQEVIN FCKTNGAFDP 400
TTMGTVPNVG LMAQKAEEYG SHDKTFEVQE NGTMRVRDAE GNVLMQHDVE 450
KGDIWRACQT KDAPIKDWVK LGVTRARNSG TPAVFWLDAE RAHDNELRKK 500
VKLYLQDHDL EGLEIHIMSY NEAIRFSMER MMRGQDTISV SGNVLRDYLT 550
DLFPIMELGT SAKMLSIVPM LNGGGMYETG AGGSAPKHVQ QLQEENYLRW 600
DSLGEFLATA VSFEELGIKQ DNAKAKVLAA ALDRATEQLL DNNKSPSRKV 650
GDIDNRGSHF YLTMYWAQAL ATQTDDAELA DKFASVAKAL VENESKIVEE 700
LNSVQGKDAG LEGYYHMDLD AVTKVMRPSA TFNEILAAI 739
Length:739
Mass (Da):82,315
Last modified:May 31, 2011 - v1
Checksum:iE7DAF5E2241CCA22
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002583 Genomic DNA. Translation: ADZ90609.1.
RefSeqiYP_004312445.1. NC_015276.1.

Genome annotation databases

EnsemblBacteriaiADZ90609; ADZ90609; Marme_1336.
GeneIDi10335396.
KEGGimme:Marme_1336.
PATRICi47227410. VBIMarMed159599_1384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002583 Genomic DNA. Translation: ADZ90609.1 .
RefSeqi YP_004312445.1. NC_015276.1.

3D structure databases

ProteinModelPortali F2JWD6.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADZ90609 ; ADZ90609 ; Marme_1336 .
GeneIDi 10335396.
KEGGi mme:Marme_1336.
PATRICi 47227410. VBIMarMed159599_1384.

Phylogenomic databases

KOi K00031.
OMAi SIVKLMQ.

Enzyme and pathway databases

BioCyci MMED717774:GCPW-1368-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1.

Entry informationi

Entry nameiF2JWD6_MARM1
AccessioniPrimary (citable) accession number: F2JWD6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: July 9, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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