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F2JWD6

- F2JWD6_MARM1

UniProt

F2JWD6 - F2JWD6_MARM1

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Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Marme_1336

Organism
Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei145 – 1451SubstrateUniRule annotation
Sitei254 – 2541Critical for catalysisUniRule annotation
Metal bindingi349 – 3491Magnesium or manganese
Sitei419 – 4191Critical for catalysisUniRule annotation
Binding sitei546 – 5461SubstrateUniRule annotation
Metal bindingi547 – 5471Magnesium or manganese
Metal bindingi551 – 5511Magnesium or manganese

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciMMED717774:GCPW-1368-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Marme_1336Imported
OrganismiMarinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1)Imported
Taxonomic identifieri717774 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesMarinomonas
ProteomesiUP000001062: Chromosome

Structurei

3D structure databases

ProteinModelPortaliF2JWD6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni132 – 1398Substrate bindingUniRule annotation

Phylogenomic databases

KOiK00031.
OMAiSIVKLMQ.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

F2JWD6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKHTIYYTL TDEAPALATA SLLPIFQAFA KEADINLQLT DISLAARVLS
60 70 80 90 100
LFTDRLPEDK QVEDGLSFLG ELTADPDANF IKLPNISASI PQLTATIKEL
110 120 130 140 150
QSQGYEIPDY PEAPATDEEK EINSRYSKVL GSAVNPVLRQ GNSDRRAPAA
160 170 180 190 200
VKGFARKHPH SMGKWQKTSQ THADYMRDGD FFSSEQSVTM DKAQEVRIEF
210 220 230 240 250
VNKSGEVDVK KTLPLLEGEV LDGMRMSASK LRDFFEQSLQ EAKEAGIMWS
260 270 280 290 300
LHVKATMMKV SHPIVFGHAV TVYYKEVWDK FGDLFDELGV NPNNGIGSVY
310 320 330 340 350
DKIKTLPQST QDEILESIHD CYEHRPEIAM VDSVRGITNL HVPSDVIVDA
360 370 380 390 400
SMPAMIRSSG KMWGRDGKTK DTKAVMPEST YARIYQEVIN FCKTNGAFDP
410 420 430 440 450
TTMGTVPNVG LMAQKAEEYG SHDKTFEVQE NGTMRVRDAE GNVLMQHDVE
460 470 480 490 500
KGDIWRACQT KDAPIKDWVK LGVTRARNSG TPAVFWLDAE RAHDNELRKK
510 520 530 540 550
VKLYLQDHDL EGLEIHIMSY NEAIRFSMER MMRGQDTISV SGNVLRDYLT
560 570 580 590 600
DLFPIMELGT SAKMLSIVPM LNGGGMYETG AGGSAPKHVQ QLQEENYLRW
610 620 630 640 650
DSLGEFLATA VSFEELGIKQ DNAKAKVLAA ALDRATEQLL DNNKSPSRKV
660 670 680 690 700
GDIDNRGSHF YLTMYWAQAL ATQTDDAELA DKFASVAKAL VENESKIVEE
710 720 730
LNSVQGKDAG LEGYYHMDLD AVTKVMRPSA TFNEILAAI
Length:739
Mass (Da):82,315
Last modified:May 31, 2011 - v1
Checksum:iE7DAF5E2241CCA22
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002583 Genomic DNA. Translation: ADZ90609.1.
RefSeqiYP_004312445.1. NC_015276.1.

Genome annotation databases

EnsemblBacteriaiADZ90609; ADZ90609; Marme_1336.
GeneIDi10335396.
KEGGimme:Marme_1336.
PATRICi47227410. VBIMarMed159599_1384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002583 Genomic DNA. Translation: ADZ90609.1 .
RefSeqi YP_004312445.1. NC_015276.1.

3D structure databases

ProteinModelPortali F2JWD6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADZ90609 ; ADZ90609 ; Marme_1336 .
GeneIDi 10335396.
KEGGi mme:Marme_1336.
PATRICi 47227410. VBIMarMed159599_1384.

Phylogenomic databases

KOi K00031.
OMAi SIVKLMQ.

Enzyme and pathway databases

BioCyci MMED717774:GCPW-1368-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1Imported.

Entry informationi

Entry nameiF2JWD6_MARM1
AccessioniPrimary (citable) accession number: F2JWD6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: October 29, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3