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Protein

Guanylate kinase

Gene

gmk

Organism
Polymorphum gilvum (strain LMG 25793 / CGMCC 1.9160 / SL003B-26A1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotationSAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi28 – 35ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.8UniRule annotationSAAS annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotationImported
Ordered Locus Names:SL003B_2399Imported
OrganismiPolymorphum gilvum (strain LMG 25793 / CGMCC 1.9160 / SL003B-26A1)Imported
Taxonomic identifieri991905 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaPolymorphum
Proteomesi
  • UP000008130 Componenti: Chromosome

Subcellular locationi

F2J1M3:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi991905.SL003B_2399.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 200Guanylate kinase-likeInterPro annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4108UHA. Bacteria.
COG0194. LUCA.
KOiK00942.
OMAiYGTLKSE.
OrthoDBiPOG091H01Q4.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F2J1M3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPDATKGAMM TSASAEAQRR GLMLVLSSPS GAGKSTIARL LLEKEDTIEL
60 70 80 90 100
SISVTTRPRR SSEIDGVHYH FVSPERFDQM RERGELLEWA EVHGNFYATP
110 120 130 140 150
RDPVETALKA GRDVLFDIDI QGTFQLYERM REDVVSVFIL PPSIAEMKSR
160 170 180 190 200
LHRRAEDTEE VILRRLKTAV GEMRHWAEYD YVVVNDDLGR AYEGVRAILR
210 220 230
AERLKQSRSP AIGGFIDGML ADLRQELGEV
Length:230
Mass (Da):26,008
Last modified:May 31, 2011 - v1
Checksum:iE35BB541E5DA69BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002568 Genomic DNA. Translation: ADZ70824.1.

Genome annotation databases

EnsemblBacteriaiADZ70824; ADZ70824; SL003B_2399.
KEGGipgv:SL003B_2399.
PATRICifig|991905.3.peg.2460.

Similar proteinsi

Entry informationi

Entry nameiF2J1M3_POLGS
AccessioniPrimary (citable) accession number: F2J1M3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: September 27, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported