F2ILM1 (F2ILM1_VIBCL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Elongation factor Tu HAMAP-Rule MF_00118
Short name=EF-Tu HAMAP-Rule MF_00118

Gene names

Name:	tuf HAMAP-Rule MF_00118
ORF Names:	VCLMA_A0280 EMBL AEA77594.1

Organism

Vibrio cholerae LMA3984-4 EMBL AEA77594.1

Taxonomic identifier

935297 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio › Vibrio cholerae

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118 RuleBase RU000325
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00118
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00118.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. HAMAP-Rule MF_00118 RuleBase RU000325

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm HAMAP-Rule MF_00118
Ligand	GTP-binding RuleBase RU000323 HAMAP-Rule MF_00118 Nucleotide-binding
Molecular function	Elongation factor HAMAP-Rule MF_00118 RuleBase RU000325 EMBL AEA77594.1
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	19 – 26	8	GTP By similarity HAMAP-Rule MF_00118
	Nucleotide binding	81 – 85	5	GTP By similarity HAMAP-Rule MF_00118
	Nucleotide binding	136 – 139	4	GTP By similarity HAMAP-Rule MF_00118

Sequences

	Sequence		Length	Mass (Da)
	F2ILM1 [UniParc]. Last modified May 31, 2011. Version 1. Checksum: BF0DE31A00618B36	FASTA	394	43,126
	10 20 30 40 50 60 MSKEKFERTK PHVNVGTIGH VDHGKTTLTA AICTVLAKVY GGKARDFASI DNAPEERERG 70 80 90 100 110 120 ITINTSHVEY DTPNRHYAHV DCPGHADYVK NMITGAAQMD GGILVVAATD GPMPQTREHI 130 140 150 160 170 180 LLGRQVGIPY IIVFMNKCDM VDDEELLELV EMEVRELLSE YDFPGDDLPV IQGSALGALN 190 200 210 220 230 240 GEAQWEAKIV ELAEALDTYI PEPERAVDMA FLMPIEDVFS IQGRGTVVTG RIERGILKVG 250 260 270 280 290 300 DEVAIVGIKE TVKTTCTGVE MFRKLLDEGR AGENVGALLR GTKREEVERG QVLAKPGSIT 310 320 330 340 350 360 PHTKFESEVY VLSKDEGGRH TPFFKGYRPQ FYFRTTDVTG SIELPEGVEM VMPGDNVKMV 370 380 390 VDLIAPIAMD EGLRFAIREG GRTVGAGVVA KIIA

References

[1]	Chaparro J., Cerdeira L., Al-Dilaimi A., Barbosa M.S., de Oliveira R.S., Ranieri A., Garcia B., Coimbra N., Sa L.L.C., Tauch A., Schneider M.P., McCulloch J., Silva A. Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: LMA3894-4 EMBL AEA77594.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002555 Genomic DNA. Translation: AEA77594.1.
RefSeq	YP_005632992.1. NC_017270.1.
3D structure databases
ProteinModelPortal	F2ILM1.
SMR	F2ILM1. Positions 4-394.
ModBase	Search...
Proteomic databases
PRIDE	F2ILM1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEA77594; AEA77594; VCLMA_A0280.
GeneID	12267474.
KEGG	vcl:VCLMA_A0280.
PATRIC	54230352. VBIVibCho179000_0293.
Phylogenomic databases
KO	K02358.
Enzyme and pathway databases
BioCyc	VCHO935297:GLMO-306-MONOMER.
Family and domain databases
HAMAP	MF_00118_B. EF_Tu_B.
InterPro	IPR000795. EF_GTP-bd_dom. IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF52540. SSF52540. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F2ILM1_VIBCL

Accession

Primary (citable) accession number: F2ILM1

Entry history

Integrated into UniProtKB/TrEMBL:	May 31, 2011
Last sequence update:	May 31, 2011
Last modified:	May 29, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)