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F2I8N9

- F2I8N9_AERUA

UniProt

F2I8N9 - F2I8N9_AERUA

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Aerococcus urinae (strain ACS-120-V-Col10a)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Note: Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei566 – 5661UniRule annotation

GO - Molecular functioni

  1. kinase activity Source: UniProtKB-KW
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, LyaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciAURI866775:GI3R-1960-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:HMPREF9243_1989Imported
OrganismiAerococcus urinae (strain ACS-120-V-Col10a)Imported
Taxonomic identifieri866775 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesAerococcaceaeAerococcus
ProteomesiUP000008129: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F2I8N9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPVKKLEANI TQSMVKEEVH VLKEILDDTT HKMVGDQVFE MIQGLVDLSM
60 70 80 90 100
KEDYKQLESV VAQLSNDEMV VVSRYFSILP LLINISEDVD FAYEINYQNN
110 120 130 140 150
TDQDYLGKLA LTIDRVSQSD QAKEILEHVN VVPVLTAHPT QVQRKTILEL
160 170 180 190 200
TNQIHHLLRK YHDVKAGVVN RDKWYTDLRR YVEIIMQTDI IREKKLTVRN
210 220 230 240 250
EITNVTAYYN NSLIRAITKL SRQYRHLAAQ KGIELDQAKP ITMGMWIGGD
260 270 280 290 300
RDGNPYVTAE TLLLSATTQS EVILNYYIDK VHKLYRNFSL STTLVDISPA
310 320 330 340 350
MEALAAKSND KSIYRENEPY RRAFHYIKAK LEQNLVEVKN GLKRDDQAPT
360 370 380 390 400
PSYQNAEAFK ADLLVIKESL LAHGEDALLT GDFNELVEAI DIFGFYLATI
410 420 430 440 450
DMRQDSSVNE ACVAELLKSA KIVDDYSSLS EPEKVKVLLK ELLEDPRPLS
460 470 480 490 500
SAHSEKSELL EKELKIFKTA RFLKDQLGDQ VIKQHIISHT ESVSDMFELA
510 520 530 540 550
IMLKEVGLVD PKQARVQIVP LFETIEDLEN AQGIMEEFLS YDLVQNWIKA
560 570 580 590 600
NHGYQEVMLG YSDSNKDGGY LSSVWTLYKV QQELTQLGED HGIKITFIHG
610 620 630 640 650
RGGTVGRGGG PSYEAVTSQP FGSIKDRIRL TEQGEIIENK YGNQDVAYYN
660 670 680 690 700
LEMLVSAAIS RIVPGSVDKK ADVEDFYQDM DDIVHYSNGV YRHLVFDTPE
710 720 730 740 750
FYDYFFEATP IKEVSSLNIG SRPAARKTIT EISGLRAIPW VFSWSQTRIM
760 770 780 790 800
FPGWYGVGSA FKHFIDQDAG NLEKLQAMYQ SWPFFHSLLS NVDMVLSKSN
810 820 830 840 850
MNIAEQYAQL AESEEVRAVF TTIRDEWQLT KDILLAIENH NEFLATNPSL
860 870 880 890 900
RASLDYRLPY FNVLNYIQIE LIKRLRHNEL DEDYEKLIHT TINGIATGLR

NSG
Length:903
Mass (Da):103,123
Last modified:May 31, 2011 - v1
Checksum:i0D2023A7C1C5FD87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002512 Genomic DNA. Translation: AEA01718.1.
RefSeqiYP_004322100.1. NC_015278.1.

Genome annotation databases

EnsemblBacteriaiAEA01718; AEA01718; HMPREF9243_1989.
GeneIDi10344770.
KEGGiaur:HMPREF9243_1989.
PATRICi47224442. VBIAerUri166521_1882.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002512 Genomic DNA. Translation: AEA01718.1 .
RefSeqi YP_004322100.1. NC_015278.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEA01718 ; AEA01718 ; HMPREF9243_1989 .
GeneIDi 10344770.
KEGGi aur:HMPREF9243_1989.
PATRICi 47224442. VBIAerUri166521_1882.

Phylogenomic databases

KOi K01595.

Enzyme and pathway databases

BioCyci AURI866775:GI3R-1960-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Aerococcus urinae strain ACS-120-V-Col10a."
    Durkin A.S., Madupu R., Radune D., Hostetler J., Torralba M., Gillis M., Methe B., Sutton G., Nelson K.E.
    Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ACS-120-V-Col10aImported.

Entry informationi

Entry nameiF2I8N9_AERUA
AccessioniPrimary (citable) accession number: F2I8N9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: November 26, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3