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F2HST8 (F2HST8_BRUMM) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Elongation factor Tu HAMAP-Rule MF_00118

Short name=EF-Tu HAMAP-Rule MF_00118
Gene names
Name:tuf-2 EMBL ADZ66322.1
Synonyms:tuf HAMAP-Rule MF_00118
Ordered Locus Names:BM28_A1246 EMBL ADZ66322.1, BM28_A1261 EMBL ADZ66337.1
OrganismBrucella melitensis (strain M28) [Complete proteome] [HAMAP] EMBL ADZ66322.1
Taxonomic identifier941967 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. RuleBase RU000325 HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. RuleBase RU000325 HAMAP-Rule MF_00118

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding19 – 268GTP By similarity HAMAP-Rule MF_00118
Nucleotide binding76 – 805GTP By similarity HAMAP-Rule MF_00118
Nucleotide binding131 – 1344GTP By similarity HAMAP-Rule MF_00118

Sequences

Sequence LengthMass (Da)Tools
F2HST8 [UniParc].

Last modified May 31, 2011. Version 1.
Checksum: ED4CDF37183A900E

FASTA39142,605
        10         20         30         40         50         60 
MAKSKFERTK PHVNIGTIGH VDHGKTSLTA AITKFFGEFK AYDQIDAAPE ERARGITIST 

        70         80         90        100        110        120 
AHVEYETANR HYAHVDCPGH ADYVKNMITG AAQMDGAILV VSAADGPMPQ TREHILLARQ 

       130        140        150        160        170        180 
VGVPAIVVFL NKCDQVDDAE LLELVELEVR ELLSKYEFPG DEIPIIKGSA LAALEDSSKE 

       190        200        210        220        230        240 
LGEDAIRNLM DAVDSYIPTP ERPIDQPFLM PIEDVFSISG RGTVVTGRVE RGIVKVGEEV 

       250        260        270        280        290        300 
EIVGIKATTK TTVTGVEMFR KLLDQGQAGD NIGALIRGVG REDVERGQVL CKPGSVKPHT 

       310        320        330        340        350        360 
KFKAEAYILT KDEGGRHTPF FTNYRPQFYF RTTDVTGVVT LPAGTEMVMP GDNVAMDVTL 

       370        380        390 
IVPIAMEEKL RFAIREGGRT VGAGIVSSII E 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequences of Brucella melitensis strains M28 and M5-90, with different virulence backgrounds."
Wang F., Hu S., Gao Y., Qiao Z., Liu W., Bu Z.
J. Bacteriol. 193:2904-2905(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: M28 EMBL ADZ66322.1.
[2]Fangkun W., Zhigao B., Sen H., Yuzhe G., Zujian Q.
Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: M28 EMBL ADZ66322.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002459 Genomic DNA. Translation: ADZ66322.1.
CP002459 Genomic DNA. Translation: ADZ66337.1.
RefSeqYP_005597331.1. NC_017244.1.
YP_005597346.1. NC_017244.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADZ66322; ADZ66322; BM28_A1246.
ADZ66337; ADZ66337; BM28_A1261.
GeneID12283748.
12283764.
KEGGbmz:BM28_A1246.
bmz:BM28_A1261.
PATRIC47100087. VBIBruMel176544_1244.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK02358.

Enzyme and pathway databases

BioCycBMEL941967:GL9M-1266-MONOMER.
BMEL941967:GL9M-1282-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF2HST8_BRUMM
AccessionPrimary (citable) accession number: F2HST8
Entry history
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: April 16, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)