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F2HST8

- F2HST8_BRUMM

UniProt

F2HST8 - F2HST8_BRUMM

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Protein

Elongation factor Tu

Gene
tuf-2, tuf, BM28_A1246, BM28_A1261
Organism
Brucella melitensis (strain M28)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarityUniRule annotation
Nucleotide bindingi76 – 805GTP By similarityUniRule annotation
Nucleotide bindingi131 – 1344GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciBMEL941967:GL9M-1266-MONOMER.
BMEL941967:GL9M-1282-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tuf-2Imported
Synonyms:tufUniRule annotation
Ordered Locus Names:BM28_A1246Imported, BM28_A1261Imported
OrganismiBrucella melitensis (strain M28)Imported
Taxonomic identifieri941967 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000007457: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF2HST8.
SMRiF2HST8. Positions 2-390.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK02358.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F2HST8-1 [UniParc]FASTAAdd to Basket

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MAKSKFERTK PHVNIGTIGH VDHGKTSLTA AITKFFGEFK AYDQIDAAPE    50
ERARGITIST AHVEYETANR HYAHVDCPGH ADYVKNMITG AAQMDGAILV 100
VSAADGPMPQ TREHILLARQ VGVPAIVVFL NKCDQVDDAE LLELVELEVR 150
ELLSKYEFPG DEIPIIKGSA LAALEDSSKE LGEDAIRNLM DAVDSYIPTP 200
ERPIDQPFLM PIEDVFSISG RGTVVTGRVE RGIVKVGEEV EIVGIKATTK 250
TTVTGVEMFR KLLDQGQAGD NIGALIRGVG REDVERGQVL CKPGSVKPHT 300
KFKAEAYILT KDEGGRHTPF FTNYRPQFYF RTTDVTGVVT LPAGTEMVMP 350
GDNVAMDVTL IVPIAMEEKL RFAIREGGRT VGAGIVSSII E 391
Length:391
Mass (Da):42,605
Last modified:May 31, 2011 - v1
Checksum:iED4CDF37183A900E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002459 Genomic DNA. Translation: ADZ66322.1.
CP002459 Genomic DNA. Translation: ADZ66337.1.
RefSeqiYP_005597331.1. NC_017244.1.
YP_005597346.1. NC_017244.1.

Genome annotation databases

EnsemblBacteriaiADZ66322; ADZ66322; BM28_A1246.
ADZ66337; ADZ66337; BM28_A1261.
GeneIDi12283748.
12283764.
KEGGibmz:BM28_A1246.
bmz:BM28_A1261.
PATRICi47100087. VBIBruMel176544_1244.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002459 Genomic DNA. Translation: ADZ66322.1 .
CP002459 Genomic DNA. Translation: ADZ66337.1 .
RefSeqi YP_005597331.1. NC_017244.1.
YP_005597346.1. NC_017244.1.

3D structure databases

ProteinModelPortali F2HST8.
SMRi F2HST8. Positions 2-390.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADZ66322 ; ADZ66322 ; BM28_A1246 .
ADZ66337 ; ADZ66337 ; BM28_A1261 .
GeneIDi 12283748.
12283764.
KEGGi bmz:BM28_A1246.
bmz:BM28_A1261.
PATRICi 47100087. VBIBruMel176544_1244.

Phylogenomic databases

KOi K02358.

Enzyme and pathway databases

BioCyci BMEL941967:GL9M-1266-MONOMER.
BMEL941967:GL9M-1282-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. EFACTOR_GTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete genome sequences of Brucella melitensis strains M28 and M5-90, with different virulence backgrounds."
    Wang F., Hu S., Gao Y., Qiao Z., Liu W., Bu Z.
    J. Bacteriol. 193:2904-2905(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M28Imported.
  2. Fangkun W., Zhigao B., Sen H., Yuzhe G., Zujian Q.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: M28Imported.

Entry informationi

Entry nameiF2HST8_BRUMM
AccessioniPrimary (citable) accession number: F2HST8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: September 3, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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