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F2HIZ5 (F2HIZ5_LACLV) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length189 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124 SAAS SAAS020633

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124 SAAS SAAS020633.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124 RuleBase RU004165

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding85 – 884ATP By similarity HAMAP-Rule MF_00124

Sites

Active site861Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1431Zinc By similarity HAMAP-Rule MF_00124
Metal binding1461Zinc By similarity HAMAP-Rule MF_00124
Metal binding1801Zinc By similarity HAMAP-Rule MF_00124
Metal binding1831Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
F2HIZ5 [UniParc].

Last modified May 31, 2011. Version 1.
Checksum: CF50B257CBA9B014

FASTA18921,423
        10         20         30         40         50         60 
MAQLYFKYGT MNSGKSIEIL KVAHNYEEQG KPVLLMTSSL DTRAGVGTVA SRIGMKAEAV 

        70         80         90        100        110        120 
AIDEEMSVFD YVNSLPAKPF CVLIDEAQFL NKKHVYDFAR VVDELNVPVM AFGLKNDFRN 

       130        140        150        160        170        180 
ELFEGSKYLL LLADKIEEIK TICWYCSKKA TMVIRTIDGK PVYEGEQLQI GGNETYIPVC 


RKHYFKPEI 

« Hide

References

[1]"Complete genome sequence of Lactococcus lactis subsp. lactis CV56, a probiotic strain isolated from the vaginas of healthy women."
Gao Y., Lu Y., Teng K.L., Chen M.L., Zheng H.J., Zhu Y.Q., Zhong J.
J. Bacteriol. 193:2886-2887(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CV56 EMBL ADZ63165.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002365 Genomic DNA. Translation: ADZ63165.1.
RefSeqYP_005867899.1. NC_017486.1.

3D structure databases

ProteinModelPortalF2HIZ5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADZ63165; ADZ63165; CVCAS_0503.
GeneID12476602.
KEGGllt:CVCAS_0503.
PATRIC47138343. VBILacLac178659_0519.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00857.
OMARTICHCG.

Enzyme and pathway databases

BioCycLLAC929102:GLFG-539-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF2HIZ5_LACLV
AccessionPrimary (citable) accession number: F2HIZ5
Entry history
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: April 16, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)